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Coronavirus

Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case Report

From Critical Care Explorations. Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case ReportG966

Coronavirus, COVID-19

Pharmacotherapy in Coronavirus Disease 2019 and Risk of Secondary Infections: A Single-Center Case Series and Narrative Review

From Critical Care Explorations. The authors sought to evaluate the impact of pharmacologic approach to coronavirus disease 2019 within the ICU on secondary infections and clinical outcomes.

Coronavirus, COVID-19

Performance Analysis of the National Early Warning Score and Modified Early Warning Score in the Adaptive COVID-19 Treatment Trial Cohort

From Critical Care Explorations.  In this study, the authors sought to validate prognostic scores in coronavirus disease 2019 including National Early Warning Score, Modified Early Warning Score, and age-based modifications, and define their performance characteristics.

Coronavirus, COVID-19, Diagnosis and Testing

Cardiopulmonary Exercise Testing in Critically Ill Coronavirus Disease 2019 Survivors: Evidence of a Sustained Exercise Intolerance and Hypermetabolism

From Critical Care Explorations.  In this study, the authors found prolonged reduced exercise capacity up to 6 months in critically ill coronavirus disease 2019 survivors. This disability did not result from residual pulmonary or cardiac dysfunction but rather from a metabolic disorder characterized by a sustained hypermetabolism and an impaired oxygen utilization.

Coronavirus, COVID-19, Diagnosis and Testing

Right Ventricular Dysfunction and Its Association With Mortality in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome

From Critical Care Medicine  In this article, the authors assessed whether right ventricular dilation or systolic impairment is associated with mortality and/or disease severity in invasively ventilated patients with coronavirus disease 2019 acute respiratory distress syndrome.

ARDS, Coronavirus, COVID-19

What are the long-term effects of COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, Post COVID-19

Can you address some of the issues regarding the AstraZeneca and Johnson & Johnson vaccines being prothrombotic in pregnancy?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, OB/GYN, Vaccines

Do you have any experience with pregnancy during COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, OB/GYN

Have any studies been done with immunoglobulin instead of prolactin?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, Therapies

Are there any nutritional requirements or recommendations for COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, Supportive Care

How would you address the recent literature about prolactin as an immunomodulator for COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, Therapies

What doses of dexamethasone, antivirals, and immunomodulators do you recommend?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, Therapies

What do you recommend when you are consulted about a patient in the emergency department who is suspected of having COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Clinical presentations, Coronavirus, COVID-19

What do you think of the concept of silent hypoxia or happy hypoxia?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, Hemodynamic Support

When should emergency department physicians admit patients to the ICU and when should they admit patients to the ward?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, Transport

How should a patient be managed who does not look terrible and has oxygen saturation 83% and low blood pressure?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021.

Coronavirus, COVID-19, Hemodynamic Support, Ventilatory Support

What are the first steps when a patient is admitted to the emergency department?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 9th, 2021

Coronavirus, COVID-19, Disaster Preparedness

Soluble Suppression of Tumorigenicity-2 Associates With Ventilator Dependence in Coronavirus Disease 2019 Respiratory Failure

From Critical Care Explorations. In this study, the authors hypothesized that elevated soluble suppression of tumorigenicity-2 concentrations, a marker of pulmonary epithelial injury, reflects ongoing lung injury in acute hypoxemic respiratory failure due to coronavirus disease 2019 and associate with continued ventilator dependence.

Coronavirus, COVID-19, Ventilatory Support

Letter to the Editor: Lung Abscess in Critically Ill Coronavirus Disease 2019 Patients With Ventilator-Associated Pneumonia: A French Monocenter Retrospective Study

From Critical Care Explorations. In this Letter to the Editor, the authors report that 17 of 119 coronavirus disease 2019 patients (14%) with ventilator-associated pneumonia developed a lung abscess.

Coronavirus, COVID-19, Ventilatory Support

Online Letter to the Editor: Higher Than Expected Severity-Adjusted Mortality in ICU Patients With Coronavirus Disease 2019: Time to Consider the Contributions of Pandemic-Related Transformations in Structure and Process

From Critical Care Medicine. In this Online Letter to the Editor, the author responds to the article by Higgins et al. entitled “Coronavirus Disease 2019 ICU Patients Have Higher-Than-Expected Acute Physiology and Chronic Health Evaluation-Adjusted Mortality and Length of Stay Than Viral Pneumonia ICU Patients.”

Coronavirus, COVID-19

Technology and Disasters: The Evolution of the National Emergency Tele-Critical Care Network

From Critical Care Medicine. In this Invited Foreword, the authors describe the origins, development, and proof-of-concept testing of the National Emergency Tele-Critical Care Network (NETCCN), a system intended to deliver expertise anywhere needed, at a moment’s notice.

Coronavirus, COVID-19, Telemedicine

Tracheostomy for Coronavirus Disease 2019 Patients on Mechanical Ventilation Should Not Be Arbitrarily Delayed

From Critical Care Medicine. This Editorial accompanies an article by Angel et al. entitled “Tracheostomy for Coronavirus Disease 2019 Patients Requiring Mechanical Ventilation.”

Coronavirus, COVID-19, Ventilatory Support

Editorial: Prone Positioning in Coronavirus Disease 2019: Just Do It!

From Critical Care Medicine. This Editorial accompanies the article by Mathews et al. entitled “STOP-COVID Investigators. Prone Positioning and Survival in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Respiratory Failure.”

Coronavirus, COVID-19, Proning

Early Intubation and Increased Coronavirus Disease 2019 Mortality: A Propensity Score–Matched Retrospective Cohort Study

From Critical Care Explorations. In this observational study, the authors found that iwithin 48 hours of triage, as well as at any time point in the hospital course, was associated with increased mortality in coronavirus disease 2019 patients.

Coronavirus, COVID-19, Intubation

Respiratory Physiology of Prone Positioning With and Without Inhaled Nitric Oxide Across the Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Severity Spectrum

From Critical Care Explorations. In this observational study, the authors found that prone positioning improves oxygenation across the acute positive respiratory distress syndrome severity spectrum, irrespective of supine respiratory system compliance, end-expiratory pressure, or body mass index. There was a greater relative benefit among patients with more severe disease. Prone positioning confers an additive benefit in oxygenation among patients treated with inhaled nitric oxide.

Coronavirus, COVID-19, Proning

Impact of Nonpharmaceutical Interventions on ICU Admissions During Lockdown for Coronavirus Disease 2019 in New Zealand—A Retrospective Cohort Study

From Critical Care Medicine.  In this study, the authors found that the he institution of nonpharmaceutical interventions was associated with a significant decrease in elective and acute ICU admissions and ICU resource use. These findings may help hospitals and health authorities planning for surge capacities and elective surgery management in future pandemics.

Coronavirus, COVID-19, Therapies

Validation of a Crisis Standards of Care Model for Prioritization of Limited Resources During the Coronavirus Disease 2019 Crisis in an Urban, Safety-Net, Academic Medical Center

From Critical Care Medicine. In Massachusetts, triage guidelines were designed based on acute illness and chronic life-limiting conditions. In this study, the authors sought to retrospectively validate this protocol to cohorts of critically ill patients from their hospital.

Coronavirus, COVID-19, Resource Allocation, Triage

Operationalizing Ethical Guidance for Ventilator Allocation in Minnesota: Saving the Most Lives or Exacerbating Health Disparities?

From Critical Care Explorations. In this article, the authors note that the Ventilator Allocation Score can accurately identify patients with high rates of short-term mortality. However, these high mortality patients only represent 27% of all the patients who died, limiting the utility of the score for allocation of scarce resources. The score may unfairly prioritize older patients and inadvertently exacerbate racial health disparities through the inclusion of specific comorbidities such as end stage renal disease. Triage frameworks that include age should be considered. Purposeful efforts, the authors say, must be taken to ensure that triage protocols do not perpetuate or exacerbate prevailing inequities.

Coronavirus, COVID-19, Resource Allocation, Ventilatory Support

Renal Replacement Therapy for COVID-19 Patients

This resource details an the usage of renal replacement therapy for COVID-19 patients.

This is SCCM curated COVID-19 microlearning content.

AKI/Renal, Coronavirus, COVID-19

Extracorporeal Blood Purification for COVID-19 and Beyond

This resource details an the usage of extracorporeal blood purification for COVID-19.

This is SCCM curated COVID-19 microlearning content.

AKI/Renal, Coronavirus, COVID-19

Awake Proning with High Flow Nasal Cannula in COVID-19 ARDS

This resource details an the usage of awake proning with high flow nasal cannula in COVID ARDS.
This is SCCM curated COVID-19 microlearning content.

Coronavirus, COVID-19, Ventilatory Support

Epidemiological and Clinical Characterization of Superinfections in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Explorations. Prevalence of superinfections in coronavirus disease 2019 patients requiring mechanical ventilation was high in this series, and bacterial superinfections were independently associated with ICU or 28-day mortality (whichever comes first).

Coronavirus, COVID-19, Ventilatory Support

Examination of Early CNS Symptoms and Severe Coronavirus Disease 2019: A Multicenter Observational Case Series

From Critical Care Explorations. In this observational study, the authors found that early CNS symptoms, and pecifically encephalopathy, are differentially associated with risk of severe coronavirus disease 2019 and may serve as an early marker for differences in clinical disease course.

Coronavirus, COVID-19

Scarce Resource Allocation in a Pandemic: A Protocol to Promote Equity, Timeliness, and Transparency

From Critical Care Explorations. Drawing on expertise in critical care medicine, bioethics, and political science, the authors propose a decision-making protocol to ensure fairness in the resolution of conflict, timely decision-making, and accountability to improve system response.

Coronavirus, COVID-19, Resource Allocation

Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia

From Critical Care Medicine. The authors describe the successful recovery from multiple and life-threatening venous thrombosis after ChAdOx1 nCoV-19 vaccination.

Anticoagulation, Coronavirus, COVID-19, Vaccines

Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2–Related Multisystem Inflammatory Syndrome in Children With Shock

From Critical Care Medicine. In this article, the authors found that endothelial dysfunction is associated with severe acute respiratory syndrome coronavirus 2–related multisystem inflammatory syndrome in children with shock and may constitute one of the underlying mechanisms.

Coronavirus, COVID-19, pediatrics

Return to Work After Coronavirus Disease 2019 Acute Respiratory Distress Syndrome and Intensive Care Admission: Prospective, Case Series at 6 Months From Hospital Discharge

From Critical Care Medicine. In this Online Brief Report, the authors describe rates of return to work versus unemployment following coronavirus disease 2019 acute respiratory distress syndrome requiring intensive care admission.

Coronavirus, COVID-19, Post COVID-19

Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation

From Critical Care Explorations. This is a case report on the use of awake extracorporeal membrane oxygenation as a “treatment” for barotrauma due to severe acute respiratory distress syndrome in a coronavirus disease 2019 patient, without the need for invasive mechanical ventilation.

Case Presentations, Coronavirus, COVID-19, ECMO, Ventilatory Support

Development and Validation of ARC, a Model for Anticipating Acute Respiratory Failure in Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this predictive modeling report, the authors sought to evaluate factors predictive of clinical progression among coronavirus disease 2019 patients following admission, and whether continuous, automated assessments of patient status may contribute to optimal monitoring and management.

Coronavirus, COVID-19

Online Letter to the Editor: Optimal Management of Thrombotic Complications in Patients With Coronavirus Disease 2019

From Critical Care Medicine. This Online Letter to the Editor was written in response to an article by Mirsadraee et al. entitled “Prevalence of Thrombotic Complications in ICUTreated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning.”

Coronavirus, COVID-19, Diagnosis and Testing

Online Letter to the Editor: Reasons for the Overuse of Sedatives and Deep Sedation for Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Medicine. This Online Letter to the Editor was written in response to an article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Acute Respiratory Distress Syndrome: A Retrospective Cohort Study.”

Coronavirus, COVID-19, Sedation, Ventilatory Support

Online Letter to the Editor: The Janus Face of Coronavirus Disease 2019–Associated Coagulopathy

From Critical Care Medicine. This Online Letter to the Editor is in response to an article by Doyle et al. entitled “A comparison of thrombosis and hemorrhage rates in patients with severe respiratory failure due to coronavirus disease 2019 and influenza requiring extracorporeal membrane oxygenation.”

Anticoagulation, ARDS, Coronavirus, COVID-19, ECMO

Online Letter to Editor: Optimal Patient Selection for the Prophylactic Anticoagulation Therapy in Patients With Coronavirus Disease 2019

From Critical Care Medicine. This Online Letter to the Editor was written in response to an article by Santoro et al. entitled “Anticoagulation Therapy in Patients With Coronavirus Disease 2019: Results From a Multicenter International Prospective Registry (Health Outcome Predictive Evaluation for Corona Virus Disease 2019 [HOPE-COVID19]).”

Coronavirus, COVID-19, Therapies

Editorial: Glucocorticoid-Glucocorticoid Receptor Response to Severe Acute Respiratory Syndrome Coronavirus 2

From Critical Care Medicine. This Editorial accompanies an article by Vassiliou et al. entitled “Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients.”

Coronavirus, COVID-19

Editorial: The Long Road to Normalcy Following Survival From COVID-19–Associated Acute Respiratory Distress Syndrome

From Critical Care Medicine. This editorial accompanies an article by Carenzo et al. entitled “Return to Work After Coronavirus Disease 2019 Acute Respiratory Distress Syndrome and Intensive Care Admission: Propsective, Case-Series at 6 Months From Hospital Discharge” and calls for future studies to identify evidence for best practice during treatment of acute phase of infection to mitigate some of the long lasting effects as well as factors to help maximize rehabilitation efforts to help survivors to return to their everyday lives.

Coronavirus, COVID-19, Post COVID-19

Editorial: Coronavirus Disease 2019: There Is a Heart Between the Lungs

From Critical Care Medicine. This Editorial was written in response to the article by Chotalia et al. “Right Ventricular Dysfunction and Its Association With Mortality in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome.”

Cardiovascular, Coronavirus, COVID-19, Diagnosis and Testing

Editorial: Utility of Coronavirus Disease 2019 Immune Profiling for the Clinician at the Bedside

From Critical Care Medicine. This Editorial was written in response to the article by de Roquetaillade et al. entitled “Comparison of Circulating Immune Cells Profiles and Kinetic Between Coronavirus Disease 2019 and Bacterial Sepsis,” which explores the relationship between the immune profile of COVID-19 patients and clinical outcomes.

Coronavirus, COVID-19, Sepsis

Coronavirus Disease 2019: A Pandemic Spawning an Infodemic

From Pediatric Critical Care Medicine. In this Special Article, the authors make a call for the field of pediatric critical care to “move forward.” They note that, over a short period, some of the best science and resources have been applied to children with COVID-19 or MIS-C, and that now clinicians and scientists have a different objective: to translate what they learn and know into the highest level of care for patients.

Coronavirus, COVID-19

Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Medicine. In this study, the authors found that ICU coronavirus disease 2019 patients showed upregulated glucocorticoid receptor alpha and glucocorticoid-inducible leucine zipper expression, along with cortisol levels, compared with ICU noncoronavirus disease 2019 patients. Thus, they concluded, on ICU admission, critical coronavirus disease 2019 appears to be associated with hypercortisolemia, and increased synthesis of glucocorticoid receptor alpha and induced proteins.

Coronavirus, COVID-19

Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?

From Critical Care Medicine. In this Editorial, the authors discuss the article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome” and suggest that reemploying the use of evidence-based strategies developed over the past 20 years through rigorous controlled trials is one of the best mechanisms by which to help critically ill adults with COVID-19 liberate from the ICU and transition toward recovery and survivorship. 

Coronavirus, COVID-19, Sedation

Editorial: Advancing Telehealth-Based Screening for Postintensive Care Syndrome: A Coronavirus Disease 2019 Paradigm Shift

From Critical Care Medicine. In this Editorial, the authors discuss the article by Martillo et al. entitled “Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic.” 

Coronavirus, COVID-19, Post COVID-19, Telemedicine

Online Letter to the Editor: Postcoronavirus Disease Chronic Fatigue Is Frequent and Not Only Restricted to Hospitalized Patients

From Critical Care Medicine. This Online Letter to the Editor was written in response to a paper by Martillo et al. entitled “Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic,’ in which the authors reported a high-proportion of patients suffering from chronic fatigue 1 month after discharge from hospital for ICU-treated coronavirus disease 2019.

Coronavirus, COVID-19, Post COVID-19

Can you comment on the use of palliative care in patients with COVID-19 in the emergency department or ICU? When should we start reaching out to these colleagues?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19, Post COVID-19

What is your opinion of the benefits of zinc?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19, Therapies

What is your opinion of the benefits of vitamin D?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19, Therapies

If a patient develops hypotension in the emergency department, how should this be addressed?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19

What is the best approach to acute COVID-19 management in the emergency department?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19

Should BiPAP be used in patients with COVID-19 or should it be avoided? If you decide to intubate a patient, which parameters should be used and what initial ventilatory settings do you recommend?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19, Intubation

Do patients with dementia have increased delirium? What is the best way to address this issue at admission to decrease patient suffering later?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19, Delirium

CDC Resources: Disaster

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Disaster

Coronavirus, COVID-19

CDC Resources: Cardiovascular

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Cardiovascular

Comorbidities, Coronavirus, COVID-19

IDSA Resources: Quality and Patient Safety

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Infectious Diseases Society of America (IDSA) COVID-19 Real-Time Learning Network. These resources are categorized as Quality and Patient Safety

Coronavirus, COVID-19, Post COVID-19

IDSA Resources: Disaster

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Infectious Diseases Society of America (IDSA) COVID-19 Real-Time Learning Network. These resources are categorized as Disaster

Coronavirus, COVID-19

Regarding anticoagulation, in NHS trusts in the UK, COVID-19 routine blood screening includes D-dimer. They perform a lot of CT pulmonary angiography, which are negative for central pulmonary embolism. What do comparable U.S. data show?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Anticoagulation, Coronavirus, COVID-19

Can you expand on the use of anticoagulation in patients who have been diagnosed with COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Anticoagulation, Coronavirus, COVID-19

How should delirium be addressed in ICU patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19, Delirium

What processes should be established to update family members on the patient’s progress, especially if the patient is declining?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Communication, Coronavirus, COVID-19

What are basic principles of managing patients when they are transferred to the ICU setting?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19, Transport

What is your opinion on management of patients’ health in the emergency department?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on May 12th, 2021

Coronavirus, COVID-19

A Review of Acute Respiratory Distress Syndrome and COVID-19

Is COVID-19 just atypical acute respiratory distress syndrome (ARDS)? Multidisciplinary faculty will discuss the research and varying answers to this question in this SCCM webcast. During this webcast faculty covered evidence-based best practices for airway management now that more is known about COVID-19. The Society of Critical Care Medicine and the American Association of Respiratory Care partnered to produce this webinar on COVID-19. Webcast Recorded on Wednesday, May 26, 2021

ARDS, Coronavirus, COVID-19

Coronavirus Disease 2019: A Pandemic Spawning an Infodemic

From Pediatric Critical Care Medicine. In this Special Article, the authors make a call for the field of pediatric critical care to “move forward.” They note that, over a short period, some of the best science and resources have been applied to children with COVID-19 or MIS-C, and that now clinicians and scientists have a different objective: to translate what they learn and know into the highest level of care for patients.

Coronavirus, COVID-19

Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?

From Critical Care Medicine. In this Editorial, the authors discuss the article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome” and suggest that reemploying the use of evidence-based strategies developed over the past 20 years through rigorous controlled trials is one of the best mechanisms by which to help critically ill adults with COVID-19 liberate from the ICU and transition toward recovery and survivorship.

Coronavirus, COVID-19, Sedation

Editorial: Advancing Telehealth-Based Screening for Postintensive Care Syndrome: A Coronavirus Disease 2019 Paradigm Shift

From Critical Care Medicine. In this Editorial, the authors discuss the article by Martillo et al. entitled “Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic.” The Editorial authors conclude that questions remain about when and how to screen for PICS and whether severe COVID-19 survivors have unique symptoms or trajectories compared with non-COVID-19 critical illness survivors, and they emphasize that the main public health message is clear -- critical illness, in general, and severe COVID-19, specifically, are life changing and the critical care community needs to do all it can to prevent the development of PICS and raise awareness.

Coronavirus, COVID-19, Post COVID-19, Telemedicine

Online Letter to the Editor: Postcoronavirus Disease Chronic Fatigue Is Frequent and Not Only Restricted to Hospitalized Patients

From Critical Care Medicine. This Online Letter to the Editor was written in response to a paper by Martillo et al. entitled Postintensive Care Syndrome in Survivors of Critical Illness Related to Coronavirus Disease 2019: Cohort Study From a New York City Critical Care Recovery Clinic,’ in which the authors reported a high-proportion of patients suffering from chronic fatigue 1 month after discharge from hospital for ICU-treated coronavirus disease 2019.

Coronavirus, COVID-19, Post COVID-19

Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Medicine. In this study, the authors found that ICU coronavirus disease 2019 patients showed upregulated glucocorticoid receptor alpha and glucocorticoid-inducible leucine zipper expression, along with cortisol levels, compared with ICU noncoronavirus disease 2019 patients. Thus, they concluded, on ICU admission, critical coronavirus disease 2019 appears to be associated with hypercortisolemia, and increased synthesis of glucocorticoid receptor alpha and induced proteins.

Coronavirus, COVID-19, Sedation

CDC Resources: Hematology

SCCM’s COVID-19 Rapid Resource Center now links to pertinent content from the Centers for Disease Control and Prevention (CDC). These resources are categorized as Hematology

Anticoagulation, Coronavirus, Vaccines

Tocilizumab for the Treatment of Severe COVID-19 Pneumonia in Critically Ill Patients: Trendy or Tried-and-True?

This resource details an the usage of tocilizumab as a treatment for severe COVID-19.
This is SCCM curated COVID-19 microlearning content.

Coronavirus, COVID-19, Therapies

Is Microthrombosis the Main Pathology in Coronavirus Disease 2019 Severity?—A Systematic Review of the Postmortem Pathologic Findings

From Critical Care Explorations.  In this systematic review, the authors attempted to retrieve and report the findings of postmortem studies including the histopathologic data of deceased coronavirus disease 2019 patients and to review the manifestations of coronavirus disease 2019–associated thrombotic pathologies reported in the recent literature. Diffuse alveolar damage was the most predominant feature in the lungs of coronavirus disease 2019 patients who underwent postmortem assessment. Widespread pulmonary microthrombosis and extensive pulmonary angiogenesis, in addition to frequent pulmonary and extrapulmonary microthrombotic and thromboembolic findings in patients with coronavirus disease 2019, appear to be consistent with the disease-specific hypercoagulability.

Anticoagulation, Coronavirus, COVID-19

Letter to the Editor: Less Lumping and More Splitting: Why We Should Not Call COVID Sepsis

From Critical Care Medicine. This Letter to the Editor is in response to an editorial by Shappell et al. entitled “Does Severe Acute Respiratory Syndrome Coronavirus 2 Cause Sepsis?”

Coronavirus, COVID-19

Comparison of Circulating Immune Cells Profiles and Kinetics Between Coronavirus Disease 2019 and Bacterial Sepsis

From Critical Care Medicine.  In this article the authors present a longitudinal analysis of the immune response in coronavirus disease 2019 patients, its correlation with outcome, and comparison between severe coronavirus disease 2019 patients and septic patients. They conclude that severe coronavirus disease 2019 is associated with a unique immune profile as compared with sepsis. Several immune features are associated with outcome and suggest that immune monitoring of coronavirus disease 2019 might be helpful for patient management.

Coronavirus, COVID-19, Sepsis