A Case-Control Study of Prone Positioning in Awake and Nonintubated Hospitalized Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this study, the authors found no significant association with reduced risk of invasive mechanical ventilation or inhospital mortality after adjusting for baseline severity of illness and oxygenation status.

Editorial: The Pandemic Paradox: A Celebrated Exhaustion

From Critical Care Medicine . In this editorial, the author discussed burnout and its impact on clinicians.

Coronavirus Disease 2019 Immediately Increases Burnout Symptoms in ICU Professionals

Fron Critical Care Medicine . This study shows that overburdening of ICU professionals during an extended period of time leads to symptoms of burnout. 

Severe Acute Respiratory Syndrome Coronavirus-2 Infections in Critical Care Staff: Beware the Risks Beyond the Bedside

From Critical Care Medicine . In this study, the authors found that staff who developed coronavirus disease 2019 were less likely to have caught it from their patients in critical care. Other staff, other areas of the hospital, and the wider community are more likely sources ...

Outcomes of Patients With COVID-19 Receiving Organ Support Therapies: The International VIRUS Registry

From Critical Care Medicine . The authors describe the outcomes of hospitalized patients in a multicenter, international coronavirus disease 2019 registry.

Critical Ethics: How to Balance Patient Autonomy With Fairness When Patients Refuse Coronavirus Disease 2019 Testing

From Critical Care Explorations . In this review articles, the authors set out to identify the most ethical way a given healthcare system may respond to a patient’s refusal to undergo coronavirus disease 2019 testing.

Dysphagia in Patients With Severe Coronavirus Disease 2019—Potential Neurologic Etiologies

From Critical Care Explorations . In this case series, the authors investigate dysphagia in patients with severe coronavirus disease 2019.

Association Between Early Invasive Mechanical Ventilation and Day-60 Mortality in Acute Hypoxemic Respiratory Failure Related to Coronavirus Disease-2019 Pneumonia

From Critical Care Explorations . In this study, the authors assessed the effect of early invasive mechanical ventilation in coronavirus disease-2019 with acute hypoxemic respiratory failure on day-60 mortality.

The Association of Preinfection Daily Oral Anticoagulation Use and All-Cause in Hospital Mortality From Novel Coronavirus 2019 at 21 Days: A Retrospective Cohort Study

From Critical Care Explorations . In this retrospective study, the authors sought to understand the association of preinfection daily oral anticoagulation use and the short-term mortality of patients hospitalized with coronavirus disease 2019.

An 18-Year-Old Survivor With a Body Mass Index of 73.9 kg/m2 on Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019: A Collaborative Multidisciplinary Effort

From Critical Care Explorations . In this case report, the authors describe a case of acute respiratory distress syndrome secondary to coronavirus disease 2019 infection in setting of super morbid obesity (body mass index 73.9 kg/m2) with the successful use of extracorporeal ...

Presence of Spontaneous Echo Contrast on Point-of-Care Vascular Ultrasound and the Development of Major Clotting Events in Coronavirus Disease 2019 Patients

From Critical Care Explorations . In this study, the authors assessed for the prevalence and consequences of spontaneous echo contrast on point-of-care vascular ultrasound in coronavirus disease 2019.

Evaluation of Hypertriglyceridemia in Critically Ill Patients With Coronavirus Disease 2019 Receiving Propofol

From Critical Care Explorations . In this study, the authors report the prevalence of, and evaluate risk factors for, the development of hypertriglyceridemia (defined as a serum triglyceride level of > 400 mg/dL) in patients with coronavirus disease 2019 who received propofol.

Correlation of Respiratory Physiologic Parameters in Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Explorations . In this article, the authors report simultaneously measured respiratory parameters (static lung compliance, alveolar dead space ventilation, and shunt fraction) in 14 patients with advanced coronavirus disease 2019-related acute respiratory d...

The Effects of ICU Crisis Reorganization on Outcomes in Patients Not Infected With Coronavirus Disease 2019 During the Initial Surge of the Coronavirus Disease 2019 Pandemic

From Critical Care Explorations . In this study, the authors determined if ICU reorganization due to the coronavirus disease 2019 pandemic affected outcomes in critically ill patients who were not infected with coronavirus disease 2019.

Tocilizumab in Coronavirus Disease 2019-Related Critical Illness: A Propensity Matched Analysis

From Critical Care Explorations .  In this study, the authors evaluate ICU mortality at 28 days in patients with severe hypoxemic respiratory failure due to coronavirus disease 2019 infection who received tocilizumab. 

Severe Acute Respiratory Syndrome Coronavirus-2-Associated Acute Kidney Injury: A Narrative Review Focused Upon Pathophysiology

From Critical Care Medicine . In this article, the authors conclude that a personalized approach to each patient with acute kidney injury based on the timing and severity of disease is necessary in order to provide appropriate treatment.

Prevalence of Thrombotic Complications in ICU-Treated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning

From Critical Care Medicine . In this study, the authors looked for the true prevalence of thrombotic complications in critically ill patients with severe coronavirus disease 2019 on the ICU, with or without extracorporeal membrane oxygenation.

Capillary Leukocytes, Microaggregates, and the Response to Hypoxemia in the Microcirculation of Coronavirus Disease 2019 Patients

From Critical Care Medicine . In this study, the authors hypothesized that coronavirus disease 2019 patients exhibit sublingual microcirculatory alterations caused by inflammation, coagulopathy, and hypoxemia.

Safety and Outcomes of Prolonged Usual Care Prone Position Mechanical Ventilation to Treat Acute Coronavirus Disease 2019 Hypoxemic Respiratory Failure

From Critical Care Medicine . In this study, the authors found that prolonged prone position ventilation was feasible and relatively safe with implications for wider adoption in treating critically ill coronavirus disease 2019 patients and acute respiratory distress syndrome ...

Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery

From Critical Care Medicine . The authors sought to establish the core outcome measures for respiratory failure, multiple organ failure, shortness of breath, recovery, and mortality for trials in coronavirus disease 2019.