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SCCM is thrilled to bring world-renowned thought leaders to the 2024 Critical Care Congress to discuss innovative developments and hot topics in critical care. Read the thought leaders’ own previews of their upcoming sessions!
This Concise Critical Appraisal explores a meta-analysis showing that prone positioning is beneficial for patients meeting criteria for venovenous extracorporeal membrane oxygenation (ECMO), especially when initiated within five days after ECMO initiation. When initiated within five days, patients had lower intensive care unit (ICU) mortality rates, higher likelihood of being discharged alive, shorter ECMO duration, and cumulative 90-day probability of being discharged from the ICU.
Clazakizumab is a monoclonal antibody against human interleukin-6 that may benefit patients hospitalized with severe or critical COVID-19 accompanied by hyperinflammation. Although not yet FDA approved, clinical trials are underway worldwide. Samantha Gambles Farr, MSN, NP-C, CCRN, RNFA, is joined by Bonnie E. Lonze, MD, PhD, to discuss the article, “A Randomized Double-Blinded Placebo Controlled Trial of Clazakizumab for the Treatment of COVID-19 Pneumonia With Hyperinflammation.”
From Critical Care Explorations The authors determine the factors associated with mortality in venovenous extracorporeal membrane oxygenation (V-V ECMO) patients with COVID-19 infection and provide an updated report of clinical outcomes for patients treated with V-V ECMO for COVID-19 in Minnesota.
From Critical Care Explorations In this Letter to the Editor the authors concluded that the pattern of albumin kinetics may be predictive of outcome in COVID-19 and sepsis-induced ARDS.
From Critical Care Medicine In this Letter to the Editor the authors write in reponse to Ibarra-Estrada et al.
From Critical Care Medicine In this Letter to the Editor the authors write in response to Chotalia et al.
From Critical Care Medicine The authors quantify the response to prone position, describe the differences between coronavirus disease 2019 acute respiratory distress syndrome and acute respiratory distress syndrome, and explore variables associated with survival.
Eric Pacht, MD, discuss an editorial published in the September issue of Critical Care Medicine, "Enteral therapy to decrease morbidity and improve survival in acute respiratory distress syndrome: Its time has come."
Gregory Martin, MD, discusses some of the topics from his presentation during the 36th Critical Care Congress, "Furosemide and Albumin in ARDS."
Todd Fraser, MD, speaks with Daniel F. McAuley, MD, about his article, “Simvastatin in the Acute Respiratory Distress Syndrome,” published in the October 2014 New England Journal of Medicine.
Margaret Parker, MD, MCCM, speaks with Aaron C. Spicer, MD, MAS, about the article, “A Simple and Robust Bedside Model for Mortality Risk in Pediatric Patients With Acute Respiratory Distress Syndrome,” published in the October 2016 issue of Pediatric Critical Care Medicine.
Margaret Parker, MD, MCCM, speaks with John J. Marini, MD, about the Congress session "Clinician Pro/Con: Paralysis and Proning in ARDS," which was presented at the 45th Critical Care Congress in Orlando, Florida.
Kyle B. Enfield, MD, and Craig M. Lilly, MD, discuss the newly released guidance for vaping-associated respiratory distress syndrome, published in Critical Care Explorations (Lilly C, et al. Crit Care Explor. 2020;2(2): e0081).
Clinicians are working to understand and formulate an effective treatment for COVID-19-associated acute respiratory distress syndrome (Marini J. Crit Care Med. 2020 May 13; Epub ahead of print).
From Critical Care Explorations The authors describe hospital variation in use of “guideline-based care” for acute respiratory distress syndrome (ARDS) due to COVID-19.
From Critical Care Explorations The authors studied impact of paralysis on prone-induced gas exchange improvements and provider attitudes regarding paralytics.
From Critical Care Explorations In this Letter to the Editor the authors investigated the effect of prone ventilation on right ventricular (RV) function of intubated patients with COVID-19–associated acute respiratory distress syndrome.
In this "Breathe Easy Elevator Pitch" podcast, Dr. Siva Bhavani interviews Dr. David Furfaro, and they discuss the study "Latent Class Analysis Reveals COVID-19-related ARDS Subgroups", recently published in the Blue Journal.
From Critical Care Explorations In this paper, the authors aimed to characterize the kinetics of serum albumin in critically ill patients with coronavirus disease 2019 compared with critically ill patients with sepsis-induced acute respiratory distress syndrome.
This Concise Critical Appraisal explores an article published in Critical Care Medicine on a program at Cooper University Hospital in Camden, New Jersey, USA, that implemented a previously published successful ECMO model, in which ECMO cannulation primarily performed by cardiothoracic surgeons is transitioned to medical intensivist-led cannulation. This article is significant in advancing the role of the medical intensivist in the cannulation of patients who require ECMO.
From Critical Care Explorations. In this Commentary, that authors discuss bronchoscopy in patients with coronavirus disease 2019 and conclude that bronchoscopy should be strongly considered when clinically indicated.
From Critical Care Medicine. This Editorial accompanies an article by Belletti et al. entitled “Barotrauma in Coronavirus Disease 2019 Patients Undergoing Invasive Mechanical Ventilation: A Systematic Literature Review.”
Is COVID-19 just atypical acute respiratory distress syndrome (ARDS)? Multidisciplinary faculty will discuss the research and varying answers to this question in this SCCM webcast.
From Critical Care Medicine In this article, the authors assessed whether right ventricular dilation or systolic impairment is associated with mortality and/or disease severity in invasively ventilated patients with coronavirus disease 2019 acute respiratory distress syndrome.
From Critical Care Medicine. This Online Letter to the Editor is in response to an article by Doyle et al. entitled “A comparison of thrombosis and hemorrhage rates in patients with severe respiratory failure due to coronavirus disease 2019 and influenza requiring extracorporeal membrane oxygenation.”
Is COVID-19 just atypical acute respiratory distress syndrome (ARDS)? Multidisciplinary faculty will discuss the research and varying answers to this question in this SCCM webcast. During this webcast faculty covered evidence-based best practices for airway management now that more is known about COVID-19. The Society of Critical Care Medicine and the American Association of Respiratory Care partnered to produce this webinar on COVID-19. Webcast Recorded on Wednesday, May 26, 2021
From Critical Care Explorations The authors sought to determine the variation in outcomes and respiratory mechanics between the subjects who are intubated earlier versus later in their coronavirus disease 2019 course.
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on March 10, 2021
This resource details methods for awake self-proning for COVID-19 patients with ARDS. This is SCCM curated COVID-19 microlearning content.
From Critical Care Explorations In this study, the authors sought to determine similarities and differences in clinical characteristics between the patients from two waves of severe acute respiratory syndrome coronavirus-2 infection at the time of hospital admission, as well as to identify risk biomarkers of coronavirus disease 2019 severity.
From Critical Care Explorations. In this case series, the authors investigate dysphagia in patients with severe coronavirus disease 2019.
From Critical Care Explorations. In this article, the authors report simultaneously measured respiratory parameters (static lung compliance, alveolar dead space ventilation, and shunt fraction) in 14 patients with advanced coronavirus disease 2019-related acute respiratory distress syndrome.
From Critical Care Medicine. In this study, the authors looked for the true prevalence of thrombotic complications in critically ill patients with severe coronavirus disease 2019 on the ICU, with or without extracorporeal membrane oxygenation.
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on January 13, 2021
From Critical Care Medicine Contrary to previously held beliefs surrounding the coronavirus 19 pandemic, this study found that, in critically ill patients infected with coronavirus disease 2019, people of color had a lower 28-day mortality than Whites with no difference in hospital mortality, ICU length of stay, or rates of intubation.
This resource details how to manage cytokine storm and ARDS by comparing corticosteriod dosing strategies for COVID-19 patients. This is SCCM curated COVID-19 microlearning content.
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on December 9, 2020.
From Critical Care Explorations In this study, the authors found that patients with coronavirus disease 2019 acute respiratory distress syndrome experienced a higher rate of propofol-associated hypertriglyceridemia than noncoronavirus disease 2019 acute respiratory distress syndrome patients, even after accounting for differences in propofol administration.
From Critical Care Explorations The authors retrospectively evaluated cases of coronavirus disease 2019 acute respiratory distress syndrome patients and identified six patients that met the diagnosis of invasive pulmonary aspergillosis according to previously established definitions.
From Critical Care Medicine In this editorial, the author discusses the seeming benefits of using almitrine for severe hypoxia in patients with coronavirus disease 19 induced acute respiratory distress syndrome.
From Critical Care Explorations The authors evalute the use of isoflurane in patients with coronavirus disease 2019–induced acute respiratory distress syndrome.
From Critical Care Medicine The authors assessed the effect of almitrine, a selective pulmonary vasoconstrictor, on arterial oxygenation in severe acute respiratory syndrome coronavirus 2-induced acute respiratory distress syndrome.
From Critical Care Explorations. In this study, the authors investigated explored whether awake self-proning improved outcomes in coronavirus disease 2019-infected patients treated in a rural medical center with limited resources during a significant local coronavirus disease 2019 outbreak.
From Critical Care Explorations. In this Letter to the Editor, the authors state that close monitoring of patients with COVID-19 and mechanical ventilation is required; staying at the patient’s bedside is necessary to identify life-threatening asynchronies and must be resolved promptly, as well as finding strategies for prevention of asynchronies.
From Critical Care Medicine. In this study, the authors analyzed the effectiveness of high-flow nasal oxygen treatment and aimed to identify the variables predicting high-flow nasal oxygen treatment failure in coronavirus disease 2019 patients with acute hypoxemic respiratory failure.
From Critical Care Medicine. In this foreword, the authors contend that there should be no debate that SARS-CoV-2 is an important cause of sepsis and that labeling it as such is beneficial and appropriate.
From Critical Care Explorations. In this article, the authors describe three coronavirus disease 2019 patients suffering from acute respiratory distress syndrome under venovenous extracorporeal membrane oxygenation therapy and tight anticoagulation monitoring presenting a novel pattern of multifocal brain hemorrhage in various degrees in all cerebral and cerebellar lobes.
From Critical Care Medicine. In this study, the authors state their data suggest that a ""higher” positive end-expiratory pressure approach in patients with severe acute respiratory syndrome coronavirus 2 acute respiratory distress syndrome and high compliance improves oxygenation and lung aeration but may result in alveolar hyperinflation and hemodynamic alterations.
From Critical Care Explorations. The authors sought to determinewhether placental cell therapy PLacental eXpanded (PLX)-PAD (Pluristem Therapeutics, Haifa, Israel) was beneficial to treating critically ill patients suffering from acute respiratory distress syndrome due to coronavirus disease 2019.
From Critical Care Medicine. In this Viewpoints article, the authors discuss the challenges of ARDS in COVID-19 patients.
From Critical Care Medicine. In this Viewpoints article, the authors discuss the value of evidence-based, guidelines-driven care in ARDS in patients with COVID-19.
From Critical Care Explorations. In this study, the authors describe patients according to the maximum degree of respiratory support received and report their inpatient mortality due to coronavirus disease 2019.
From Critical Care Explorations. In this study, the authors adapted a high-fidelity computational simulator to develop quantitative insights into the key pathophysiologic differences between the coronavirus disease 2019 acute respiratory distress syndrome and the conventional acute respiratory distress syndrome and to assess the impact of different positive end-expiratory pressure, Fio2, and tidal volume settings.
From Critical Care Medicine. The authors report on a sedation and ventilation method used in France.
From Critical Care Medicine. The authors share the following opinions on the recruitment-response COVID-19 ARDS patients, 1) bronchiolitis, in a histologic context, is a plausible pathophysiological mechanism, and 2) a simple bedside physiologic test could potentially determine recruitment potential in resource-limited settings.
From Critical Care Explorations. As the SARS-CoV-2 pandemic develops, assays to detect the virus and infection caused by it are needed for diagnosis and management. In this article, the authors describe to clinicians how each assay is performed, what each assay detects, and the benefits and limitations of each assay.
From Criticial Care Explorations. The authors report on the use of corticosteroids in mechanically ventilated patients with SARSCoV-2 related acute respiratory distress syndrome.
From Critical Care Explorations. To do better understand the risk factors associated with pulmonary embolism in patients with COVID-19, the authors performed a post hoc analysis from the COVADIS project, a multicenter observational study gathering 21 ICUs from France and Belgium.
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.
From Pediatric Critical Care Medicine. This study aims to describe a series of children admitted to a pediatric intensive care unit in Spain, one of the countries severely affected by the coronavirus. disease 2019 (COVID-19).
From Critical Care Explorations. A letter to the editor in response to Villar et al. article on corticosteroids and COVID-19.
From Critical Care Medicine. An editorial associated with the Mauri et al. article on personalized ventilation for COVID-19 ARDS patients.
From Critical Care Medicine. Severe cases of coronavirus disease 2019 develop the acute respiratory distress syndrome, requiring admission to the ICU. This study aims to describe specific pathophysiological characteristics of acute respiratory distress syndrome from coronavirus disease 2019.
Steve Pastores, MD, co-author of the Critical Care Explorations article "Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019," answers question regarding the use of corticosteriod treatment for ARDS caused by COVID-19. This is SCCM curated COVID-19 microlearning content.
Steve Pastores, MD, co-author of the Critical Care Explorations article "Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019," discusses the disparities in the use of corticosteriod treatment for ARDS caused by COVID-19 by different organizations. This is SCCM curated COVID-19 microlearning content.
Steve Pastores, MD, co-author of the Critical Care Explorations article "Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019," discusses the use of corticosteriod treatment for ARDS caused by COVID-19. This is SCCM curated COVID-19 microlearning content.
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 15, 2020.
Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered.
Villar et al (Lancet Respir Med. 2020;8:267-276) attempted to demonstrate the effect of steroids in patients with moderate to severe acute respiratory distress syndrome (ARDS) along with modern standard ICU practices, including lung-protective mechanical ventilation.
Researchers seeking to evaluate the causes of PARDS and improve therapy options have been awarded the Discovery Research Grant, making it the first time the full grant has been awarded to a single project because of the strength of the grant.
Combes et al (N Engl J Med. 2018;378:1965-1975) set out to determine whether the use of ECMO reduced mortality in patients with ARDS when defined by one of three criteria: P/F ratio < 50 mm Hg for > 3 hours, P/F ratio < 80 mm Hg for > 6 hours, or pH < 7.25 coupled with Paco2 ≥ 60 mm Hg for > 6 hours (with respiratory rate < 35 beats/min and plateau pressure ≤ 32 cm H2O).
Am J Respir Crit Care Med. 2017 May 1;195(9):1253-1263