Adult Surviving Sepis Campaign Guidelines (Hour-1 Bundle)
Children's Surviving Sepsis Campaign Guidelines
Adult ICU Liberation Guidelines and Bundle (A-F)
Management of Adults with COVID-19
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Association of Socioeconomic Status and Pediatric Sepsis Outcomes
Children being treated for sepsis stayed in the hospital longer if they lived in low-income ZIP codes compared to those who were from high-income ZIP codes, suggests a large national study being presented at the Society of Critical Care Medicine’s 50th Critical Care Congress.
Congress, outcomes, pediatric, Sepsis
Consideration of Severe Coronavirus Disease 2019 As Viral Sepsis and Potential Use of Immune Checkpoint Inhibitors
From Critical Care Explorations. Supportive treatment and immunomodulators have a critical place in the treatment of severe patients until effective antivirals are developed. Interleukin-6 antagonists, one of the immunomodulating agents, appears to be effective in the treatment of cytokine storm, but some patients continue to have severe lymphopenia and immunosuppression.
Coronavirus, COVID-19, Sepsis
Surviving Sepsis Campaign Guidelines
Crit Care Med 2017; 45(3): 486-552
2016 Guidelines, Sepsis, Surviving Sepsis Campaign
A Global Solution for Sepsis
This session was presented during the Society of Critical Care Medicine’s (SCCM) 47th Critical Care Congress. Flavia R. Machado, MD, PhD, discusses the current limitations of our knowledge of sepsis incidence and mortality rates as well as major disparities in sepsis care around the world. She proposes interventions for reducing sepsis incidence and improving sepsis outcomes worldwide.
Concise Critical Appraisal: Early Hemostatic Management of Disseminated Intravascular Coagulopathy
This Concise Critical Appraisal delves into a study published in Pediatric Critical Care Medicine that sought to determine whether early hemostatic intervention can prevent the development of DIC and improve outcomes.
Concise Critical Appraisal, Hematology, pediatrics, Sepsis
Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery
From Critical Care Medicine. The authors sought to establish the core outcome measures for respiratory failure, multiple organ failure, shortness of breath, recovery, and mortality for trials in coronavirus disease 2019.
Clinical Trials, Coronavirus, COVID-19, Sepsis
Angelica Hale: SCCM ICU Heros Award Winner
ICU Heroes Award Winner Angelica Hale performs When You Believe by Whitney Houston.
Congress, ICU Heroes, Sepsis
Concise Critical Appraisal: Effect of Community-Acquired Pediatric Sepsis on Survivors
Killien et al (Pediatr Crit Care Med. 2019;Epub ahead of print) set out to evaluate the prevalence of health-related quality of life (HRQL) decline in pediatric survivors of community-acquired sepsis, severe sepsis, and septic shock and to determine which factors are associated with a failure to return to baseline HRQL.
Editorial: Coronavirus Disease 2019: A Tsunami of Data and a Plethora of Unanswered Questions
From Pediatric Critical Care Medicine. In this editorial, the author discusses issues emerging from the study by Bhumbra et al. (Clinical features of critical coronavirus disease 2019 in children) that are worthy of discussion and further exploration, including the predilection for racial minorities, similarities and differences to sepsis, wide expression of clinical disease, and the conundrum of providing family centered care.
Coronavirus, COVID-19, pediatrics, Sepsis
Controversies in the Early Detection and Treatment of Sepsis
This session was presented during the Society of Critical Care Medicine’s (SCCM) 47th Critical Care Congress.
Congress, Sepsis, Treatment
Concise Critical Appraisal: PERSEVERE Biomarkers in Predicting AKI in Pediatric Septic Shock
Can the biomarkers identified in the Pediatric Sepsis Biomarker Risk Model (PERSEVERE II) be used to predict acute kidney injury and renal recovery in pediatric septic shock? This Concise Critical Appraisal explores a study in which Stanski et al (Am J Respir Crit Care Med. 2020;201:848-855) sought to answer this question.
Concise Critical Appraisal, renal, sepsis, Septic Shock
Editorial: Pediatric Sepsis in the Time of Coronavirus Disease 2019
From Pediatric Critical Care Medicine. In this editorial, the author reviews ""Perspectives on Pediatric Sepsis in Patients with COVID-19"" from the Surviving Sepsis Campaign Pediatric Guidelines Taskforce authors.
Early Identification of Sepsis: The Journey Since the Sepsis on the Wards Collaborative
This article was first published in the August 2019 issue of Critical Connections. AdventHealth Shawnee Mission in Shawnee Mission, Kansas, USA, had a unique opportunity to impact the care provided to patients with sepsis in partnership with the Surviving Sepsis Campaign’s (SSC) Sepsis on the Wards Collaborative. Three years later, building on this foundation, processes are still being streamlined to improve the care of this challenging population.
Help Shape the Future of Sepsis Research on the National Level
The National Institute of General Medical Sciences (NIGMS) is changing its priorities to invest in sepsis research in a more targeted and strategic way. In an important opportunity to help shape the future of sepsis research, NIGMS has issued a request for information related to its new priorities. The request for information is found here and is due by November 15, 2019.
Congress, Research, Sepsis
Foreword: Does Severe Acute Respiratory Syndrome Coronavirus 2 Cause Sepsis?
From Critical Care Medicine. In this foreword, the authors contend that there should be no debate that SARS-CoV-2 is an important cause of sepsis and that labeling it as such is beneficial and appropriate.
ARDS, Coronavirus, COVID-19, Sepsis
Pediatric Sepsis 2018
This is a presentation from the 47th Critical Care Congress on pediatric sepsis.
Congress, On Demand, Sepsis
The Future of Sepsis Treatment
Sepsis continues to affect Americans and hospital patients across the United States. The Centers for Disease Control and Prevention (CDC) estimates that approximately 1.7 million adult Americans develop sepsis each year1; this is more than the entire population of Phoenix, the fifth-largest city in the country.2 Approximately 270,000 of these patients die from sepsis.
Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the Era of Coronavirus Disease 2019
From Pediatric Critical Care Medicine. In this article, the authors discuss the Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-associated Organ Dysfunction in Children as they relate to COVID-19.
Coronavirus, COVID-19, Pediatrics, Sepsis
SCCM Pod-403 Sepsis: The Hour-1 Bundle, the Future of Research, and More
Margaret M. Parker, MD, MCCM, and Mitchell M. Levy, MD, MCCM discuss the Hour-1 Bundle, the controversies of the Surviving Sepsis Campaign, and the future of sepsis.
Pulmonary, Research, Sepsis
Procalcitonin Exerts a Mediator Role in Septic Shock Through the Calcitonin Gene-Related Peptide Receptor
From Critical Care Medicine
The authors found that procalcitonin exerts a moderate but harmful effect on disease progression in experimental septic shock, and suggests a potential therapeutic application for calcitonin gene-related peptide receptor inhibitors in sepsis.
SCCM Pod-406 Surviving Sepsis Campaign Children's Guidelines
Margaret M. Parker, MD, MCCM, and Scott L. Weiss, MD, FCCM, discuss the release of "Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children," published in the February 2020 issue of Pediatric Critical Care Medicine (Weiss S, et al. Pediatr Crit Care Med. 2020;21(2);e52-e106).
Guidelines, Sepsis, Septic Shock
Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C
From Critical Care Medicine
The authors invesitated the safety and efficacy of megadose sodium ascorbate in sepsis.
Coronavirus, COVID-19, Sepsis, Therapies
SCCM Pod-407 Life Following Pediatric Septic Shock
Margaret M. Parker, MD, MCCM, and Jerry J. Zimmerman, MD, PhD, FCCM, talk about the trajectory of long-term mortality and significant health-related quality of life disability among children encountering septic shock.
Sepsis, Septic Shock
SCCM Pod-427 Severe COVID-19 and Sepsis
Severe COVID-19 infection can be a form of viral sepsis with occasionally concomitant bacterial infection.
Coronavirus, COVID-19, Disaster Preparedness, Sepsis
SCCM Pod-409 SSC COVID-19 Guidelines
Explore the Surviving Sepsis Campaign's Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) (Alhazzani W, et al. Crit Care Med. 2020 Mar 27; Epub ahead of print) with host Kyle B. Enfield, MD, and authors Mitchell M. Levy, MD, MCCM, and Waleed Alhazzani, MD, MSc, FRCPC.
Coronavirus, COVID-19, Guidelines, Sepsis
Sepsis and Coronavirus Disease 2019: Common Features and Anti-Inflammatory Therapeutic Approaches
From Critical Care Medicine. The authors present some common features shared by severe coronavirus disease 2019 patients and sepsis and describe proposed anti-inflammatory therapies for coronavirus disease 2019 which have been previously evaluated in sepsis.
SCCM Pod-427 Severe COVID-19 and Sepsis
Severe COVID-19 infection can be a form of viral sepsis with occasionally concomitant bacterial infection. Explore the definition of sepsis and overlap with case descriptions of patients with severe COVID-19, treatment, and more.
Sepsis and COVID-19
This presentation is an overview of sepsis management in COVID-19 patient. This is SCCM curated COVID-19 microlearning content.
SCCM Pod-VCCR10 Pathophysiology and Management of AKI
Richard Iuorio, MD, speaks with Kianoush Kashani, MD and Jim Reilly, MD about the pathophysiology and management of acute kidney injury.
AKI, Hypertension, Renal, Resuscitation, Sepsis
Validation of Inflammopathic, Adaptive, and Coagulopathic Sepsis Endotypes in Coronavirus Disease 2019
From Critical Care Medicine
The authors tested and found that a previously defined bacterial sepsis endotype classifier recapitulates the same clinical and immunological endotypes in viral sepsis (coronavirus disease 2019).
SCCM Pod-VCCR2 New Onset Atrial Fibrillation in Septic Shock
Sean P. Kane, PharmD, BCPS, speaks with Ishaq Lat, PharmD, about new onset atrial fibrillation in septic shock. In the epsiode, the issue of rate versus rhythm control is discussed as well as the need for anticoagulation among this patient population.
Anticoagulation, Sepsis, Septic Shock
SCCM Pod-VCCR6 Vasopressor Selection in Septic Shock
Sean P. Kane, PharmD, BCPS, speaks with Scott T. Benken, PharmD, BCPS-AQ Cardiology about vasopressor selection in septic shock.
Cardiology, Sepsis, Septic Shock, Vasopressors
The Sepsis Alliance aims to educate the public and healthcare professionals about sepsis.
Sepsis, Support Group, THRIVE
Sepsis: The Golden Hours; The Tipping Point
This is a presentation from the 47th Critical Care Congress on Sepsis: The Golden Hours; The Tipping Point.
Surviving Sepsis Campaign Releases First Guidelines for Sepsis in Children
This article was originally published in the Spring 2020 Issue of Critical Conectionns. The Surviving Sepsis Campaign (SCC) in February released its first guidelines for pediatric patients with sepsis, marking a new milestone in the initiative’s mission to improve sepsis care and save lives.
Guidelines, Pediatrics, Sepsis
Surviving Sepsis Collaborative Stories
Raeann M. Fuller, CCRN, MSN, RN, CNML, and Steven Simpson, MD, discuss their experience as members of the Surviving Sepsis Campaign Collaborative.
Texas Hold 'Em: Going All In for Double Coverage of Gram-Negative Sepsis
This is a presentation from the 47th Critical Care Congress on double coverage of gram-negative sepsis.
THRIVE: Recovery After a Hospitalization for Sepsis
Sepsis is the body’s overwhelming and life-threatening response to infection. This video offers strategies for sepsis survivors and their families
PICS, Sepsis, THRIVE