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Thromboelastography Profiles of Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Medicine. The authors reviewed thromboelastography studies in critically ill patients with coronavirus disease 2019 to characterize their coagulation states.


Editorial: Extracorporeal Membrane Oxygenation During the Coronavirus Disease 2019 Pandemic

From Critical Care Medicine. In this editorial, the authors discuss the important role of extracorporeal membrane oxygenation as a rescue therapy for patients with SARS-CoV-2 pneumonia associated with severe ARDS.


Coronavirus Disease 2019 Intermediate Care Units: Containing Escalation of ICUs

From Critical Care Medicine. In this Letter to the Editor, the authors share their view that - for COVID-19 patient - Intermediate Care Units (IMCUs) may be better suited for post-ICU care than ordinary hospital wards.


Timing of Intubation and Mortality Among Critically Ill Coronavirus Disease 2019 Patients: A Single-Center Cohort Study

From Critical Care Medicine. The authors examined the impact of time to intubation and use of high-flow nasal cannula on clinical outcomes in patients with coronavirus disease 2019.


International Survey to Establish Prioritized Outcomes for Trials in People With Coronavirus Disease 2019

From Critical Care Medicine. The author set out to generate a consensus-based, prioritized list of outcomes for coronavirus disease 2019 trials.


Core Outcomes Set for Trials in People With Coronavirus Disease 2019

From Critical Care Medicine. The authors aimed to establish a core outcomes set for trials in people with suspected or confirmed coronavirus disease 2019.


Myoclonus in Patients With Coronavirus Disease 2019: A Multicenter Case Series

From Critical Care Medicine. The authors describe the risk factors for and outcomes after myoclonus in a cohort of patients with coronavirus disease 2019.


Intracranial Pressure Dynamics and Cerebral Vasomotor Reactivity in Coronavirus Disease 2019 Patient With Acute Encephalitis

From Critical Care Explorations. In this article, the authors describe the intracranial pressure dynamics and cerebral vasomotor reactivity in a coronavirus disease 2019 patient with acute encephalitis treated with cerebrospinal fluid drainage and therapeutic plasma exchange.


Letter to the Editor: Concerns About the Timing and Settings of Initiating Extracorporeal Membrane Oxygenation in Patients With Severe Coronavirus Disease 2019 Pneumonia

From Critical Care Medicine. In this Letter to the Editor, the author respond to an article by Yang et al about COVID and ECMO.


Principles Guiding Nonpandemic Critical Care Research During a Pandemic

From Critical Care Medicine. In this article, the authors describe the importance of critical care clinical research that is not pandemic-focused during pandemic times; outline principles to assist in the prioritization of nonpandemic research during pandemic times; and propose a guiding framework for decisions about whether, when and how to continue nonpandemic research while still honoring the moral and scientific imperative to launch research that is pandemic-focused.


Nationwide Incidence and Outcomes of Patients With Coronavirus Disease 2019 Requiring Intensive Care in Iceland

From Critical Care Medicine. In this study from Iceland, which had early adoption of widespread testing, the authors report a lower overall ratio of ICU admissions for coronavirus disease 2019 among severe acute respiratory syndrome coronavirus 2 positive patients and a lower hospital mortality for patients treated in the ICU for coronavirus disease 2019 compared with initial reports from Italy and China.


Obesity and the Risk of Intubation or Death in Patients With Coronavirus Disease 2019

From Critical Care Medicine. In the study, obesity was an independent risk factor for intubation or death.


Critical Care for Coronavirus Disease 2019: Perspectives From the PICU to the Medical ICU

From Critical Care Medicine. The authors describe the unique perspective of pediatric intensivists caring for critically ill adults during the coronavirus disease 2019 pandemic.


Editorial: Coronavirus Disease 2019: A Tsunami of Data and a Plethora of Unanswered Questions

From Pediatric Critical Care Medicine. In this editorial, the author discusses issues emerging from the study by Bhumbra et al. (Clinical features of critical coronavirus disease 2019 in children) that are worthy of discussion and further exploration, including the predilection for racial minorities, similarities and differences to sepsis, wide expression of clinical disease, and the conundrum of providing family centered care.


Evaluation of Coronavirus Disease 2019 Severity Using Urine Biomarkers

From Critical Care Explorations. The authors conducted a study to determine whether noninvasive urine biomarkers can predict the clinical severity of coronavirus disease 2019.


Letter to the Editor: Early Clinical Experience in Using Helmet Continuous Positive Airway Pressure and High-Flow Nasal Cannula in Overweight and Obese Patients With Acute Hypoxemic Respiratory Failure From Coronavirus Disease 2019

From Critical Care Explorations. In this Letter to the Editor, the authors present their retrospective review of COVID-19 patients admitted to the ICUs within two academic urban hospitals (1,012 total hospital beds), comparing helmet continuous positive airway pressure and high-flow nasal cannula in patients with a body mass index greater than or equal to 25 kg/m2 who had persistent hypoxemia.


In Silico Modeling of Coronavirus Disease 2019 Acute Respiratory Distress Syndrome: Pathophysiologic Insights and Potential Management Implications

From Critical Care Explorations. In this study, the authors adapted a high-fidelity computational simulator to develop quantitative insights into the key pathophysiologic differences between the coronavirus disease 2019 acute respiratory distress syndrome and the conventional acute respiratory distress syndrome and to assess the impact of different positive end-expiratory pressure, Fio2, and tidal volume settings.


Letter to the Editor Treatment of Critically Ill Coronavirus Disease 2019 Patients With Adjunct Therapeutic Plasma Exchange: A Single-Center Retrospective Case Series

From Critical Care Explorations. In this Letter to the Editor, the authors describe their experience with a series of eight patients receiving adjunct therapeutic plasma exchange for severe coronavirus disease pneumonia complicated by sepsis with multiple organ dysfunction in which C-reactive protein and ferritin levels significantly decreased with therapeutic plasma exchange, whereas D-dimer decreased to a lesser degree.


Inpatient Mortality According to Level of Respiratory Support Received for Severe Acute Respiratory Syndrome Coronavirus 2 (Coronavirus Disease 2019) Infection: A Prospective Multicenter Study

From Critical Care Explorations. In this study, the authors describe patients according to the maximum degree of respiratory support received and report their inpatient mortality due to coronavirus disease 2019.


Subcutaneous Emphysema, Pneumomediastinum, and Pneumothorax in Critically Ill Patients With Coronavirus Disease 2019: A Retrospective Cohort Study

From Critical Care Explorations. In this observational study, the authors describe patients with barotrauma, which appears to be a common complication of severe coronavirus disease 2019.