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Category: Sepsis

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Albumin Kinetics in Sepsis and COVID-19

From Critical Care Explorations In this Letter to the Editor the authors concluded that the pattern of albumin kinetics may be predictive of outcome in COVID-19 and sepsis-induced ARDS.


SCCM Diagnostic Excellence Program Seeks to Transform Sepsis Care With Support of CMSS Grant

Sepsis is the leading cause of hospitalization and hospital deaths in the United States. SCCM has received a grant from the Council of Medical Specialty Societies to improve diagnostic excellence. SCCM’s Diagnostic Excellence Program focuses on providing education and technology for accurate and rapid-cycle sepsis diagnosis via webcasts, podcasts, and toolkits.


Leapfrog Dashboard Tracking of Postoperative Sepsis: An Opportunity for Quality Improvement

This article describes the new Leapfrog quality metrics and their methodology, focusing on postoperative sepsis identification and the potential impact of dashboard performance tracking moving forward. Critical care professionals routinely encounter patients with sepsis and play an integral role in the formulation and implementation of management plans for postoperative sepsis, making them key participants in this effort.


Concise Critical Appraisal: Hydrocortisone and Fludrocortisone Versus Hydrocortisone Only

Is hydrocortisone for septic shock best used alone or in combination with fludrocortisone? This Concise Critical Appraisal explores a retrospective cohort study that found that treatment with hydrocortisone plus fludrocortisone led to lower rates of mortality or discharge to hospice, hospital deaths, and fewer days on vasopressors than treatment with hydrocortisone alone.


Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the Era of Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this article, the authors discuss the Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-associated Organ Dysfunction in Children as they relate to COVID-19.


Editorial: Pediatric Sepsis in the Time of Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this editorial, the author reviews ""Perspectives on Pediatric Sepsis in Patients with COVID-19"" from the Surviving Sepsis Campaign Pediatric Guidelines Taskforce authors.
 


How have sepsis protocols or bundles been used in COVID-19 patients and what is the best way to navigate these bundles, especially regarding fluids?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on April 14th, 2021


Altered Heart Rate Variability Early in ICU Admission Differentiates Critically Ill Coronavirus Disease 2019 and All-Cause Sepsis Patients

From Critical Care Explorations  In this descriptive statistical study, heart rate variability measures were found to be statistically different across critically ill patients infected with severe acute respiratory syndrome coronavirus 2 and distinct from bacterial sepsis.


Immunothrombosis Biomarkers for Distinguishing Coronavirus Disease 2019 Patients From Noncoronavirus Disease Septic Patients With Pneumonia and for Predicting ICU Mortality

From Critical Care Explorations  This hypothesis-generating study suggests that the pathophysiology of immunothrombosis differs between coronavirus disease 2019 patients and noncoronavirus disease septic patients.


Evaluation of Albumin Kinetics in Critically Ill Patients With Coronavirus Disease 2019 Compared to Those With Sepsis-Induced Acute Respiratory Distress Syndrome

From Critical Care Explorations  In this paper, the authors aimed to characterize the kinetics of serum albumin in critically ill patients with coronavirus disease 2019 compared with critically ill patients with sepsis-induced acute respiratory distress syndrome.


Surviving Sepsis Campaign Releases 2021 Adult Sepsis Guidelines

Updated global adult sepsis guidelines, released by the Surviving Sepsis Campaign (SSC), place an increased emphasis on improving the care of sepsis patients after they are discharged from the intensive care unit (ICU) and represent greater geographic and gender diversity than previous versions. The updated guidelines are especially important today, as many who are seriously ill with COVID-19 are particularly vulnerable to sepsis.
 


SCCM Pod-471: Mitigating Diagnostic Delays and Errors With Emphasis on Sepsis

Diagnostic delays and errors are significant contributors to patient illness, injury, and death in the United States. According to the Society to Improve Diagnosis in Medicine, diagnostic errors impact nearly 12 million Americans every year, leading to prolonged hospital stays, increased nonreimbursed healthcare costs, and even more harm when combined with other medical errors.

Maureen Madden, DNP, RN, CPNP-AC, CCRN, FCCM, is joined by Mary Jo C. Grant, ACNP, PhD, FAAN, to discuss how to reduce diagnostic delays and errors, with an emphasis on sepsis. This podcast is funded by the Gordon and Betty Moore Foundation through a grant program administered by the Council of Medical Specialty Societies. 0.5 hours of accredited continuing education credit is available for this podcast through March 31, 2024. Visit sccm.org/store for details.


SCCM Pod-486: Strategies for Preventing Sepsis and Septic Shock in the Hospital Setting

Maureen A. Madden, DNP, RN, CPNP-AC, CCRN, FCCM, is joined by Craig M. Coopersmith, MD, FACS, MCCM, to discuss optimal strategies for preventing sepsis and septic shock in the hospital setting. Explore the challenges faced in integrating these strategies into hospital workflows and gain insights into the significant contributions made by multiple team members. This podcast is funded by the Gordon and Betty Moore Foundation through a grant program administered by the Council of Medical Specialty Societies. 0.25 hours of accredited continuing education credit is available for this podcast through July 30, 2024. Visit sccm.org/store for details.


SCCM Pod-489: The AIMS Trial: Battle of the Bundles, Hour-1 Versus 3-Hour

The Assessment of Implementation of Methods in Sepsis and Respiratory Failure (AIMS) Study seeks to determine the safest and most effective approach to sepsis intervention using the evidence-based Surviving Sepsis Campaign guidelines. Marilyn N. Bulloch, PharmD, BCPS, FCCM, was joined by Mitchell M. Levy, MD, MCCM, at the 2023 Critical Care Congress to discuss the goal of the AIMS Study and the elements of both the Hour-1 and 3-Hour bundles. Dr. Levy is chief of the Division of Critical Care, Pulmonary, and Sleep Medicine and professor of medicine at the Warren Alpert Medical School of Brown University. He is also the medical director of the medical ICU at Rhode Island Hospital in Providence, Rhode Island, USA.


SCCM Pod-480: Optimizing Sepsis Care Hour-1 Bundle at a Time

Marilyn N. Bulloch, PharmD, BCPS, FCCM, and Daleen Penoyer, PhD, RN, CCRP, FCNS, FAAN, FCCM, discuss how to develop and operationalize performance improvement teams to implement the Surviving Sepsis Campaign’s (SSC) Hour-1 Bundle, which was developed in 2021 to minimize time to treatment for patients with sepsis and septic shock. Explore how to overcome barriers teams encounter in implementing the bundle, including inflexibility, lack of awareness about the bundle, competing priorities, and insufficient staffing. This podcast is funded by the Gordon and Betty Moore Foundation through a grant program administered by the Council of Medical Specialty Societies.  0.25 hours of accredited continuing education credit is available for this podcast through May 31, 2024. Visit sccm.org/store for details.


SCCM Pod-427 Severe COVID-19 and Sepsis

Severe COVID-19 infection can be a form of viral sepsis with occasionally concomitant bacterial infection.


Coronavirus Disease 2019 as Cause of Viral Sepsis: A Systematic Review and Meta-Analysis

From Critical Care Medicine. The authors report that that majority of coronavirus disease 2019 patients hospitalized in the ICU meet Sepsis-3 criteria and present infection-associated organ dysfunction. 


Editorial: Quantifying the Burden of Viral Sepsis During the Coronavirus Disease 2019 Pandemic and Beyond

From Critical Care Medicine. This Editorial accompanies the article “Coronavirus Disease 2019 as a Cause of Viral Sepsis: A Systematic Review and Meta-Analysis” by Karakike et al.