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Ludwig H. Lin, MD, and Michael G.S. Shashaty, MD, MS, discuss acute kidney injury (AKI) biomarkers and whether they are ready for clinical use. Current research, key takeaway points, the history of AKI biomarkers, and challenges to adoption are reviewed.
Dr. Shashaty is an assistant professor of medicine at the University of Pennsylvania Perelman School of Medicine in Philadelphia, Pennsylvania, USA.
Kyle B. Enfield, MD, FCCM, and Azra Bihorac, MD, MS, FCCM, discuss best practices and complexities of implementing biomarkers for kidney stress and acute kidney injury (AKI) and what the future holds for AKI biomarker literature. Dr. Bihorac was a presenter on this topic at the Society's 48th Critical Care Congress. Dr. Bihorac is the R. Glenn Davis professor of medicine, surgery, and anesthesiology in the division of nephrology, hypertension, and renal transplant within the department of medicine at the University of Florida in Gainesville, Florida, USA. This podcast is part 4 of a series sponsored by Baxter Healthcare Corporation.
Ludwig H. Lin, MD, and John A. Kellum, MD, MCCM, review factors associated with renal recovery, therapies and techniques used to enhance recovery, and long-term consequences of nonrecovery in critical illness.
Dr. Kellum presented on this topic at the Society’s 48th Critical Care Congress.
Dr. Kellum is vice-chair for research and professor of critical care medicine, medicine, bioengineering, and clinical and translational science at the University of Pittsburgh in Pittsburgh, Pennsylvania, USA.
This podcast is part 3 of a series sponsored by Baxter Healthcare Corporation.
Kyle B. Enfield, MD, and Michael J. Connor Jr, MD, discuss when to start renal replacement therapy (RRT) in critically ill patients. Background studies, indicators for early RRT, and other factors that influence RRT decisions are discussed.
Dr. Connor presented on this topic at the Society’s 48th Critical Care Congress. Dr. Connor is associate professor of critical care medicine and nephrology at Emory University School of Medicine in Atlanta, Georgia, USA.
This podcast is part one of a series sponsored by Baxter Healthcare Corporation.
Ranjit Deshpande, MD, speaks with Rajit Basu, MD, MS, FCCM, about treating volume overload in the intensive care unit with renal replacement therapy. Dr. Basu presented his talk at the 47th Critical Care Congress in San Antonio, Texas.
Dr. Basu is an associate professor in the Department of Pediatrics at Emory University School of Medicine in Atlanta, Georgia. He is also the research director in the Department of Critical Care Medicine at Children’s Healthcare of Atlanta in Atlanta, Georgia.
This podcast is sponsored by Baxter Healthcare Corporation.
Ludwig Lin, MD, speaks with Azra Bihorac, MD, MS, FCCM, about the article, “Guiding AKI Prevention Using Biomarkers,” published in Critical Connections. Dr. Bihorac works as an Associate Professor of Anesthesiology, Surgery and Medicine at the University of Florida. She is also a Senior Intensivist and Nephrologist at University of Florida Health in Gainesville, Florida. In this article, Dr. Bihorac discusses the new urinary biomarker approved for risk stratification of AKI in critically ill patients, and a recommended algorithm to grade risk of AKI using clinical factors as well as the biomarker assay.
John A. Kellum, MD, FCCM, discusses how one uses RIFLE to take care of patients with acute kidney injury (AKI). He also discusses his review article, published in the April 2008 Supplement issue of Critical Care Medicine, titled “Acute Kidney Injury.” Dr. Kellum is a professor and vice chair of the department of critical care medicine at the University of Pittsburgh in Pennsylvania. He is also past president of the Acute Dialysis Quality Initiative (ADQI) and co-chair of a workgroup producing the upcoming Kidney Disease Improving Global Outcomes’ (KDIGO) clinical practice guidelines on acute kidney injury.
John Kellum, MD, FCCM, a professor at the University of Pittsburgh, discusses his article from the August 2007 issue of Critical Connections, "Preventing Acute Renal Failure."
With widespread utilization of continuous renal replacement therapy, its critical to know about how citrate may have a role. Host Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by Ashita Tolwani, MD, to review citrate and its role in the anticoagulation process and how it can decrease the likelihood of adverse events and ease clinician workload. Dr. Tolwani is a nephrologist at the University of Alabama in Tuscaloosa, Alabama, USA. This podcast is sponsored by Baxter Healthcare.
This podcast discusses patients who develop acute kidney injury (AKI) and how AKI is independently associated with mortality in critically ill infants, neonates, and larger children. Host Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by Stuart Goldstein, MD, to discuss the HF20 study, including its end points and the clinical gaps the study addresses. (Munshi R, et al. Pediatr Nephrol 2020 Dec;35:2345-2352)
Dr. Goldstein is a professor of pediatrics and director of the Center for Acute Care Nephrology at Cincinnati Children's Hospital Medical Center in Cincinnati, Ohio, USA. This podcast is sponsored by Baxter Healthcare.
Continuous renal replacement therapy (CRRT) is complex, and dosing varies among institutions. Host Michael Smith, MD, is joined by Melissa L. Thompson Bastin, PharmD, BS, BCPS, to review dosing regimens for CRRT, studies of CRRT antibiotic dosing, and CRRT utilization in COVID-19 patients. Dr. Thompson Bastin is a medical ICU and pulmonary critical care pharmacist and assistant adjunct professor at the University of Kentucky in Lexington, Kentucky, USA. This podcast is sponsored by Baxter Healthcare.
Continuous renal replacement therapy (CRRT) requires considerable involvement from the bedside nurse. Host Michael Smith, MD, is joined by Barbara McLean, MN, RN, CCNS-BC, NP-BC, CCRN, FCCM, to explore when to start CRRT, the nursing role, and other considerations and challenges. Barbara McLean is a critical care clinical nurse specialist at Grady Health System in Atlanta, Georgia, USA. This podcast is sponsored by Baxter Healthcare.
The increase in acute kidney injury in COVID-19 patients is resulting in more utilization of renal replacement therapy (RRT) and continuous renal replacement therapy (CRRT). Host Pamela M. Peeke, MD, MPH, FACP, FACSM , is joined by Michael J. Connor Jr, MD, to review RRT utilization and best practices in COVID-19, what hospitals are doing to prepare for a surge in RRT, and how to mitigate anticoaguability in CRRT. Dr. Connor is associate professor of medicine in critical care medicine and nephrology at Emory University in Atlanta, Georgia, USA. This podcast is sponsored by Baxter Healthcare.
Margaret M. Parker, MD, MCCM, speaks with Danny Hames, MD, on his article titled "Risk Factors for Mortality in Critically Ill Children Requiring Renal Replacement Therapy," published in the November 2019 issue of Pediatric Critical Care Medicine (Hames D, et al. Pediatr Crit Care Med. 2019;20;1069-1077).
Dr. Hames speaks about some of the challenges of monitoring patients with acute kidney injury, the implications of the study for pediatric intensivists, the importance of being mindful of renal function and fluid balance for ventilated patients, and areas that need further investigation.
Dr. Hames is an attending physician in the Division of Cardiovascular Critical Care in the Department of Cardiology at Boston Children’s Hospital and an instructor in the Department of Pediatrics at Harvard Medical School in Boston, Massachusetts, USA.
Dr. Fraser, MD, speaks with Bruce A. Mueller, PharmD, FCCP, FASN, about his talk presented at the 47th Critical Care Congress in San Antonio, Texas, entitled "Artificial Kidney Meets Mechanical Lung: Comanaging the Patient with Renal and Respiratory Failure."
Dr. Mueller discusses the concepts of drug dosing during renal replacement therapy. Dr. Mueller is a Professor and Associate Dean at University of Michigan College of Pharmacy in Ann Arbor, Michigan.
Todd Fraser, MD, speaks with Paul Young, FCICM, about the article, “Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial,” published in The Journal of the American Medical Association. Dr. Young is an intensivist at Wellington Regional Hospital, and Programme Director of Intensive Care at the Medical Research Institute of New Zealand in Wellington, New Zealand. In this article, Dr. Young and coauthors examine the effect of a buffered crystalloid compared with saline on renal complications on patients admitted to the ICU.
Todd Fraser, MD, speaks with John Kellum, MD, MCCM, Professor of Critical Care Medicine at the University of Pittsburgh in Pittsburgh, Pennsylvania. In this interview, Dr. Kellum discusses the concept of renal repair after acute kidney injury and its link to significant long-term outcomes in critically ill patients.
Matthew Paden, MD, discusses his Pediatric Critical Care Medicine article, “Recovery of Renal Function and Survival After Continuous Renal Replacement Therapy During Extracorporeal Membrane Oxygenation.” The study examines the role continuous renal replacement therapy has on long-term renal outcomes during extracorporeal membrane oxygenation. Paden is an assistant professor in the department of pediatrics at Emory University School of Medicine in Atlanta, Georgia.
Join host Pamela M. Peeke, MD, MPH, FACP, FACSM, as she delves into the critical topic of acute kidney injury (AKI) and its significant impact on critically ill patients. Guest Javier Neyra, MD, MSCS, offers a comprehensive overview of renal replacement therapy (RRT) in AKI, exploring the preferred modalities and technical considerations. With a focus on the benefits of continuous therapy versus hemodialysis, the discussion sheds light on indications for continuous RRT (CRRT), emphasizing the importance of early intervention and nephrology consultation. This podcast is sponsored by Baxter Healthcare Corporation.
This is presentation covers the renal issues that can attributed to COVID-19 infection. This is SCCM curated COVID-19 microlearning content.