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Category: Pulmonary

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COVID-19 Respiratory Support and Oxygenation Review

Conventional oxygen therapy is often insufficient to meet the significant oxygen needs of a patient with COVID-19 pneumonia. Several options for providing enhanced oxygen delivery have been studied throughout the COVID-19 pandemic. This webcast held on November 10, 2021, reviewed how some of these strategies are of particular use in patients with COVID-19 who have profound hypoxic respiratory failure.


Respiratory Non-Invasive Venous Waveform Analysis for Assessment of Respiratory Distress in Coronavirus Disease 2019 Patients: An Observational Study

From Critical Care Explorations. In this Original Clinical Report, the authors conclude that respiratory non-invasive venous waveform analysis respiratory index represents a novel physiologic respiratory measurement with a promising ability to triage early care and predict the need for oxygen support therapy in coronavirus disease 2019 patients.


Patients With Coronavirus Disease 2019 Requiring Invasive Mechanical Ventilation in Mexico in the First, Second, and Exponential Growth Phase of the Third Wave of the Coronavirus Disease 2019 Pandemic

From Critical Care Explorations. In this Letter to the Editor, the author discusses inhospital mortality rates in Mexico, noting that, although the inhospital mortality of hospitalized coronavirus disease 2019 patients requiring intubation during the exponential growth phase of the third wave was lower than that in the first and second waves, the inhospital mortality in coronavirus disease 2019 patients requiring invasive mechanical ventilation remained greater than 82%.


Fewer Intubations but Higher Mortality Among Intubated Coronavirus Disease 2019 Patients During the Second Than the First Wave

From Critical Care Explorations. In this study, the authors sought to compare the rate of intubation and mortality of intubated patients in our ICUs between the first and second waves of the pandemic.


Some Patients Are More Equal Than Others: Variation in Ventilator Settings for Coronavirus Disease 2019 Acute Respiratory Distress Syndrome

From Critical Care Explorations. The authors claim this to be the first study to clearly demonstrate significant practice variation between ICUs related to mechanical ventilation parameters that are under direct control by intensivists. Their effect on clinical outcomes for both coronavirus disease 2019 and other critically ill mechanically ventilated patients could have widespread implications for the practice of intensive care medicine and should be investigated further by causal inference models and clinical trials.


Dorsal Push and Abdominal Binding Improve Respiratory Compliance and Driving Pressure in Proned Coronavirus Disease 2019 Acute Respiratory Distress Syndrome

From Critical Care Explorations. Dorsal Push and Abdominal Binding Improve Respiratory Compliance and Driving Pressure in Proned Coronavirus Disease 2019 Acute Respiratory Distress Syndrome


Assessment of 28-Day In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019: An International Cohort Study

From Critical Care Explorations  This international study suggests that in patients with coronavirus disease 2019 on invasive mechanical ventilation, older age and clinically relevant variables monitored at baseline or sequentially during the course of invasive mechanical ventilation are associated with 28-day invasive mechanical ventilation mortality hazard. 


Interdisciplinary COVID-19 Ventilator Management (Infographic)

This infographic reviews strategies to develop a multiprofessional team approach to COVID-19 ventilator management with highlights from the SCCM Free webcast Interdisciplinary COVID-19 Ventilator Management.


Prone Position in COVID-19 and -COVID-19 Acute Respiratory Distress Syndrome: An International Multicenter Observational Comparative Study*

From Critical Care Medicine The authors quantify the response to prone position, describe the differences between coronavirus disease 2019 acute respiratory distress syndrome and acute respiratory distress syndrome, and explore variables associated with survival.


Airway Pressure Release Ventilation in Acute Respiratory Failure Due to COVID-19: When One Door Closes

From Critical Care Medicine In this Letter to the Editor the authors write in reponse to Ibarra-Estrada et al. 


Effect of Bougie Versus Endotracheal Tube With Stylet on Successful Tracheal Intubation

Tracheal intubation is a high-risk procedure that is frequently performed in the emergency department and intensive care unit. Failure of first-pass success (FPS) when intubating has been shown to be associated with major adverse events, so maximizing FPS is paramount for improving patient outcomes. This Concise Critical Appraisal explores a study published in JAMA that sought to determine the effect of using a bougie (tracheal tube introducer) versus an endotracheal tube with stylet when intubating.


Concise Critical Appraisal: Rapid Implementation of an Intensivist-Led VV ECMO Cannulation Program

This Concise Critical Appraisal explores an article published in Critical Care Medicine on a program at Cooper University Hospital in Camden, New Jersey, USA, that implemented a previously published successful ECMO model, in which ECMO cannulation primarily performed by cardiothoracic surgeons is transitioned to medical intensivist-led cannulation. This article is significant in advancing the role of the medical intensivist in the cannulation of patients who require ECMO.


Initial Management of Hypoxic COVID-19 Patients

COVID-19 SSC Guidelines Infographic. This rapid resource is aligned with the SSC COVID-19 Guidelines.


SCCM Pod-456 PCCM: Effects of Excessive Oxygen Supplementation

This podcast will examine a retrospective, observational cohort study that found an association between excessive oxygen supplementation in the first day of mechanical ventilation with multiple organ dysfunction syndrome on day 7 of admission and in-hospital mortality in critically ill children. Host Elizabeth H. Mack, MD, MS, FCCM, is joined by L. Nelson Sanchez-Pinto, MD, MBI, to discuss the study’s findings. (Sanchez-Pinto LN, et al. Pediatr Crit Care Med. 2022;23:89-98). Dr. Sanchez-Pinto is a pediatric critical care physician, data scientist, clinical informaticist, and healthcare technologist at the Ann and Robert H. Lurie Children's Hospital in Chicago, IL.


Concise Critical Appraisal: Timing of Prone Positioning During Venovenous ECMO for ARDS

This Concise Critical Appraisal explores a meta-analysis showing that prone positioning is beneficial for patients meeting criteria for venovenous extracorporeal membrane oxygenation (ECMO), especially when initiated within five days after ECMO initiation. When initiated within five days, patients had lower intensive care unit (ICU) mortality rates, higher likelihood of being discharged alive, shorter ECMO duration, and cumulative 90-day probability of being discharged from the ICU.


Surviving Sepsis Campaign COVID-19 Guidelines: Ventilation Recommendations Chart

COVID-19 - - Quick Reference Chart. This chart is to be used as a rapid resource when choosing ventilation options for managing COVID-19 patients.


Surviving Sepsis Campaign COVID-19 Guidelines: Hemodynamics Recommendations Chart

COVID-19 - - Quick Reference Chart. This chart is to be used as a rapid resource when choosing hemodynamic options for managing COVID-19 patients.


Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19)

Webcast participants were able to learn more about the recommendations included in the guidelines regarding infection control, laboratory diagnosis and specimens, hemodynamic support, ventilatory support


What are your thoughts about using glucocorticoids in patients with severe ARDS secondary to COVID-19 who remain intubated after 7 days?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered.