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Category: Pharmacology

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SCCM Pod-439 The Association Between Antibiotic Delay and Hospital Mortality

Rapid delivery of antibiotics is a cornerstone of sepsis therapy, although time targets for specific components of antibiotic delivery are unknown. Host Ludwig H. Lin, MD, is joined by Stephanie Parks Taylor, MD, to discuss the significance of time lead for suspected sepsis patients, how to use a generous time window wisely, and new and reconfigured technologies opportunities (Taylor SP, et al. Crit Care Med. 2021 May;49:741-747). 

Dr. Taylor is an associate professor in the Department of Internal Medicine at Atrium Health’s Carolinas Medical Center in Charlotte, North Carolina, USA. This podcast is sponsored by Biofire


SCCM Pod-205 CCM: New Pain, Agitation and Delirium Guidelines

Jeffrey Guy, MD, MSc, MMHC, speaks with Juliana Barr, MD, FCCM, lead author on the Society of Critical Care Medicine's American College of Critical Care Medicine, “Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit,” published in the January Critical Care Medicine. The guidelines provide a roadmap for developing integrated, evidence-based, and patient-centered protocols for preventing and treating pain, agitation and delirium (PAD) in critically ill patients. Bundles included in the guideline link management strategies with other intensive care unit (ICU) interventions, such as spontaneous awakening trials and early mobility protocols. Barr is an Associate ICU Medical Director at the Veterans Affairs Palo Alto Health Care System in Palo Alto, California, and Associate Professor in Anesthesia at Stanford University.


SCCM Pod-494: Mastering CRRT: Optimal Anticoagulation and Citrate Selection

Pamela M. Peeke MD, MPH, FACP, FACSM, is joined by Rajesh Speer, PharmD, MSHA, MS, to delve into continuous renal replacement therapy (CRRT) and anticoagulation. Unravel the intricacies of anticoagulation options, with an emphasis on citrate variations. Understand low- versus high-concentrate citrate and the nuances between compounding and commercially available products. Gain invaluable insights from a pharmacist’s standpoint about the ideal anticoagulation strategies for CRRT. This podcast is sponsored by Baxter Healthcare Corporation.


SCCM Pod-503: Current Concepts: Toxidromes and Illicit Drug Abuse In the ICU

This is the third episode of SCCM’s Current Concepts Series, in which authors unveil exclusive insights into the 2024 Current Concepts Course. Diane C. McLaughlin, DNP, AGACNP-BC, CCRN, FCCM, is joined by Aaron Goodwin, PA-C, MS, and Brett Hogan, ACNP, BSN, MS, RN, to discuss updates in toxidromes and illicit drug abuse in the ICU. The guests explain why this is an important topic and share their surprising discoveries while researching the topic.


SCCM Pod-376 2018 PADIS Guidelines

Kyle B. Enfield, MD, speaks with John W. Devlin, PharmD, FCCM, about the article "Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU" (Devlin JW, et al. Crit Care Med. 2018;46:e825-e873).

Dr. Devlin discusses what’s new in the 2018 guidelines, including the added topics of rehabilitation/mobilization and sleep, the guideline development process, and implementation strategies.

Dr. Devlin is an associate professor at Northeastern University in Boston, Massachusetts, USA, and has been involved in the ICU Liberation committees and collaboratives.


What are your thoughts on anticoagulation prophylaxis?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Question and Answer Webcast Series - Webcast 2 held on April 10, 2020.


Timing, Dosing, and Duration Recommendations for the Use of Corticosteroids for COVID-19 Patients

Steve Pastores, MD, co-author of the Critical Care Explorations article "Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019," discusses the timing, dosing and duration recommendations for the use of corticosteriod treatment for COVID-19. This is SCCM curated COVID-19 microlearning content.


Which Criteria Do You Consider When Deciding Whether to Use Corticosteroids?

Steve Pastores, MD, co-author of the Critical Care Explorations article "Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019," answers question regarding the use of corticosteriod treatment for ARDS caused by COVID-19. This is SCCM curated COVID-19 microlearning content.


Which Corticosteroid Is Preferred?

Steve Pastores, MD, co-author of the Critical Care Explorations article "Rationale for Prolonged Corticosteroid Treatment in the Acute Respiratory Distress Syndrome Caused by Coronavirus Disease 2019," answers question regarding the use of corticosteriod treatment for ARDS caused by COVID-19. This is SCCM curated COVID-19 microlearning content.


What new drugs are available for COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered.


Are there any updates on using steroids to treat patients with COVID-19?

In this question and answer webcast series, attendees had an opportunity to pose questions about managing critically ill patients with COVID-19 and other issues.


What are your thoughts on COVID-19 treatments?

In this question and answer webcast series, attendees had an opportunity to pose questions about managing critically ill patients with COVID-19 and other issues.


Strategies During NeuroMuscular Blocking Agent (NMBA) Shortages

This presentation covers how to manage neuromuscular blocking agent (NMBA) shortages. This is SCCM curated COVID-19 microlearning content.


Tocilizumab for Cytokine Storm in COVID-19

This presentation provides an overview of the types of strategies for enhancing sleep in patients with COVID-19. This is SCCM curated COVID-19 microlearning content.


Analgesic, Sedative, and Paralytic Strategies in COVID-19 Patients During Critical Shortages

This presentation provides an overview of strategies for triaging analgesic, sedative, and paralytic agents patients with COVID-19. This is SCCM curated COVID-19 microlearning content.


Establishing Pharmacy Services in an Alternate Care Site

This presentation discusses how to best organize a pharmacy at an alternate care site. This is SCCM curated COVID-19 microlearning content.


COVID-19 Pharmacology Debates: Anticoagulant and Immunomodulator Use

This webinar debate will cover immunomodulatory therapies and approaches to anticoagulation in patients with COVID-19. Each debate will be moderated by the Society of Critical Care Medicine (SCCM) and American Society of Health-System Pharmacists (ASHP) Presidents.


What is the role of steroids in COVID-19 patients? When should steroids be administered?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020


Consideration of Severe Coronavirus Disease 2019 As Viral Sepsis and Potential Use of Immune Checkpoint Inhibitors

From Critical Care Explorations. Supportive treatment and immunomodulators have a critical place in the treatment of severe patients until effective antivirals are developed. Interleukin-6 antagonists, one of the immunomodulating agents, appears to be effective in the treatment of cytokine storm, but some patients continue to have severe lymphopenia and immunosuppression.


Which patients should be treated with remdesivir and when should it be initiated?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.