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Category: Endocrine

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SCCM Pod-140 PCCM: Blood/Brain Barrier Permeability During Diabetic Ketoacidosis

Monica Vavilala, MD, discusses her recent article published in the May issue of Pediatric Critical Care Medicine, titled “Change in Blood-Brain Barrier Permeability During Pediatric Diabetic Ketoacidosis Treatment.” Vavilala is an associate professor of anesthesiology, pain medicine and pediatrics at Harborview Medical Center, and is the associate director of the Harborview Injury Prevention and Research Center in Seattle, Washington. She is also an adjunct associate professor of neurological surgery at the University of Washington. 

Concise Critical Appraisal: Fluid Administration and Diabetic Ketoacidosis

Kuppermann et al (N Engl J Med. 2018;378:2275-2287) sought to prospectively determine the role that fluid makeup and rate have on the development of neurologic injury in children with DKA.

SCCM Pod-358 Liberal Glycemic Control in Critically Ill Patients With Type 2 Diabetes

Ludwig Lin, MD, speaks with Palash Kar, MBBS, about the article, “Liberal Glycemic Control in Critically Ill Patients With Type 2 Diabetes: An Exploratory Study," published in Critical Care Medicine. In this article, Dr. Kar and coauthors found that in critically ill patients with type 2 diabetes and chronic hyperglycemia, liberal glycemic control appears to attenuate glycemic variability and may reduce the prevalence of moderate-severe hypoglycemia. Dr. Kar is a senior registrar in intensive care at Royal Adelaide Hospital in South Australia. Dr. Kar has no relevant disclosures. Crit Care Med. 2016; 44(9):1695-1703. Released: 1/25/18

SCCM Pod-264 44th Critical Care Congress: RESTORE Study

Margaret Parker, MD, MCCM, speaks with Martha Curley, RN, PhD, Professor of Nursing Science at the University of Pennsylvania School of Nursing in Philadelphia and Nurse Scientist at Children's Hospital in Boston. Dr. Curley discusses "Protocolized Sedation vs Usual Care in Pediatric Patients Mechanically Ventilated for Acute Respiratory Failure: A Randomized Clinical Trial," published January 2015 in The Journal of the American Medical Association. Dr. Curley presented the article on behalf of her co-investigators at the 44th Critical Care Congress in Phoenix, Arizona.

SCCM Pod-220 CCM: Dysglycemia and In-Hospital Mortality in the ICU

Jeffrey Guy, MD, MSc, MMHC, speaks with Omar Badawi, PharmD, MPH, to discuss his article published in the December Critical Care Medicine, “Association Between ICU-Acquired Dysglycemia and In-Hospital Mortality.” Study results suggest severe ICU-acquired hyperglycemia, hypoglycemia and variability are associated with a higher risk of mortality. Badawi works for Phillips Healthcare in Baltimore, Maryland, USA.

SCCM Pod-206 PCCM: Glycemic Control in Pediatric Patients

Margaret Parker, MD, FCCM, speaks with Eliotte L. Hirshberg, MD, about her article “Clinical Equipoise Regarding Glycemic Control: A Survey of Pediatric Intensivist Perceptions,” which was published in the February 2013 issue of Pediatric Critical Care Medicine. The aim of the study was to see whether adult literature had impacted pediatric intensivists practices regarding blood glucose control. Hirshberg is an assistant professor of internal medicine at the University of Utah with an adjunct assistant professor appointment in the Department of Pediatrics in Salt Lake City, Utah. Hirshberg is also board certified as both an adult and pediatric intensive care unit (ICU) physician, working at both the Primary Children’s Medical Center Pediatric ICU as well as Intermountain Medical Center’s Shock-Trauma ICU for adults.

SCCM Pod-201 CCM: New Glycemic Control Guidelines

Jeffrey Guy, MD, MSc, MMHC, speaks with Judith Jacobi, PharmD, FCCM, lead author on the new glycemic control guidelines from the Society of Critical Care Medicine's American College of Critical Care Medicine titled, “Guidelines for the Use of an Insulin Infusion for the Management of Hyperglycemia in Critically Ill Patients,” published in the December Critical Care Medicine. The task force provides suggestions for the structure of safe and effective use of insulin infusion therapy in patients requiring tight glycemic control. Jacobi is a critical care pharmacy specialist at Indiana University Health Methodist Hospital in Indianapolis, Indiana. She is also a past president of the Society of Critical Care Medicine.

Online Letter to the Editor: Understanding the Underlying Mechanisms of Hyponatremia in Coronavirus Disease 2019 Is Critical Since Treatment Varies Based on Etiology: Let Us Not Forget Critical Illness-Related Corticosteroid Insufficiency As the Treatment

From Critical Care Medicine. In this Online Letter to the Editor, the authors write in response to an article by Frontera et al. in Critical Care Medicine about etiology of hyponatremia in coronavirus disease 2019 (COVID-19) patients.

2022 Critical Care Congress Thought Leaders: Genetics and Genomics

During the 2022 Critical Care Congress, Karin Reuter-Rice, PhD, NP, FAAN, FCCM, will talk about precision health, and specifically the role omic technologies play in critical care in a thought leader session titled “Genetics and Genomics.”

Cardiopulmonary Exercise Testing in Critically Ill Coronavirus Disease 2019 Survivors: Evidence of a Sustained Exercise Intolerance and Hypermetabolism

From Critical Care Explorations.  In this study, the authors found prolonged reduced exercise capacity up to 6 months in critically ill coronavirus disease 2019 survivors. This disability did not result from residual pulmonary or cardiac dysfunction but rather from a metabolic disorder characterized by a sustained hypermetabolism and an impaired oxygen utilization.