The May 2024 issue of Pediatric Critical Care Medicine (PCCM) features articles on predicting minute ventilation needs, spiritual care training for pediatric critical care fellows, and the use of nudging for decision-making in conferences with family members. A wide variety of clinical investigations explore organ donation, epidemiology and clinical characteristics of pediatric sepsis in China, use of the Pediatric Sequential Organ Failure Assessment score, chest compression interruption in pediatric extracorporeal cardiopulmonary resuscitation, use of rotational thromboelastometry and clot waveform analysis as point-of-care-tests for disseminated intravascular coagulation diagnosis, safety and efficacy of ethanol locks for central venous catheter salvage and central line bloodstream infection prophylaxis, and tools to measure physical function in the pediatric intensive care unit (PICU). The cardiac intensive care article explores cardiac surgery-associated acute kidney injury in neonates undergoing stage 1 palliation/Norwood procedure. The issue ends with two important PCCM perspectives: one describing the tactic of supported privacy for families dealing with a patient’s end of life in the PICU and one investigating the definition of clinical full-time equivalent in U.S. PICUs.