The June 2023 issue of Pediatric Critical Care Medicine features articles on implementing primary care physicians for long-stay pediatric intensive care unit (PICU) patients, diaphragm tonic activity in PICU patients, and an analysis of pulse oximetry and arterial saturation differences by race in pediatric COVID-19 patients. Clinical investigations cover analgesia and sedation at terminal extubation, demographics associated with the first Malawian PICU, implementing a multidisciplinary PICU follow-up clinic, and analyzing anticoagulation-free periods for pediatric patients on extracorporeal membrane oxygenation. The online articles examine sepsis definitions in children worldwide, high-frequency oscillatory ventilation in critically ill children, improving efficiency and productivity in multidisciplinary surgical rounds in the pediatric cardiac ICU, and evidence for escalation of antimicrobial regimens in febrile oncology and hematopoietic stem cell transplant patients in the PICU.