The September 2024 issue of Pediatric Critical Care Medicine (PCCM) features articles on the use of a noninvasive surrogate measurement of physiologic dead space, parental decision regret in the pediatric intensive care unit (PICU), social determinants of health and health-related quality of life after pediatric septic shock, and health-related quality of life after pediatric acute respiratory distress syndrome (PARDS). Clinical investigations cover inequitable resource utilization for common pediatric PICU diagnoses in patients of color, delirium screening post-transplant, the use of driving pressure and its association with duration of mechanical ventilation and mortality, and the adjunctive use of transcutaneous carbon dioxide monitoring for ventilation in critically ill children. The PCCM trials highlight the absence of legal guardians as a barrier to enrolling PICU patients in research studies and outline the Protocol for the Prone and Oscillation Pediatric Clinical Trial (PROSpect). Lastly, the PCCM narrative this month is a raw account of life after cardiac arrest in a loved one.