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Category: Pharmacology

Cytokine Storm and ARDS - Comparison of Corticosteroid Dosing Strategies

This resource details how to manage cytokine storm and ARDS by comparing corticosteriod dosing strategies for COVID-19 patients. This is SCCM curated COVID-19 microlearning content.

   Estimated Time: 06:19 ARDS, Coronavirus, Corticosteriods, COVID-19

How do we prevent VTEs and how do we survey for them? Should patients receive standard prophylaxis? Should all ventilated patients receive full-dose anticoagulation? What are your practices and how have you approached this at your center?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on December 9, 2020.

   Estimated Time: 06:50 Anticoagulation, Coronavirus, COVID-19

What is your local practice for using Remdesivir in the ICU?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on December 9, 2020.

   Estimated Time: 03:26 min Antivirals, Coronavirus, COVID-19

Is the standard 6 milligrams of dexamethasone for up to 10 days the only option? Do all patients need this or is there any evidence for trying something different? Has there been any experience with using a higher dexamethasone dose?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on December 9, 2020.

   Estimated Time: 03:43 Coronavirus, Corticosteriods, COVID-19

What medication adjuncts can clinicians use for the patient with severe hypoxemia who is receiving 100% oxygen but only getting an oxygen reading of 90%? What are some strategies clinicians can use to reduce some of these difficulties?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on December 9, 2020.

   Estimated Time: 03:47 min Coronavirus, COVID-19, Hemodynamic Support, Therapies

Thromboembolism, Hypercoagulopathy, and Antiphospholipid Antibodies in Critically Ill Coronavirus Disease 2019 Patients: A Before and After Study of Enhanced Anticoagulation

From Critical Care Explorations In this study, the authors sought to determine the prevalence of thrombotic events, functional coagulation tests, inflammatory biomarkers, and antiphospholipid antibodies before and after enhanced anticoagulation in critically ill coronaviru...

   Estimated Time: 15:56 min Anticoagulation, Coronavirus, COVID-19

Propofol-Associated Hypertriglyceridemia in Coronavirus Disease 2019 Versus Noncoronavirus Disease 2019 Acute Respiratory Distress Syndrome

From Critical Care Explorations In this study, the authors found that patients with coronavirus disease 2019 acute respiratory distress syndrome experienced a higher rate of propofol-associated hypertriglyceridemia than noncoronavirus disease 2019 acute respiratory distre...

   Estimated Time: 23:03 min ARDS, Coronavirus, COVID-19, Therapies

Clinical Outcomes With the Use of Prophylactic Versus Therapeutic Anticoagulation in Coronavirus Disease 2019

From Critical Care Explorations In this study, the authors found an increase in inhospital mortality was observed among patients on preemptive therapeutic anticoagulation.

   Estimated Time: 21:54 min Anticoagulation, Coronavirus, COVID-19

A Propensity-Matched Cohort Study of Tocilizumab in Patients With Coronavirus Disease 2019

From Critical Care Explorations The authors assessed the impact of tocilizumab therapy and found that it was associated with significantly improved survival in coronavirus disease 2019 patients.

   Estimated Time: 23:31 Coronavirus, COVID-19, Therapies

Editorial: Coronavirus Disease 2019 Acute Respiratory Failure: Almitrine Drug Resuscitation or Resuscitating Patients by Almitrine?

From Critical Care Medicine In this editorial, the author discusses the seeming benefits of using almitrine for severe hypoxia in patients with coronavirus disease 19 induced acute respiratory distress syndrome.

   Estimated Time: 07:02 ARDS, Cardiovascular, Coronavirus, COVID-19

Delirium Incidence, Duration, and Severity in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations The authors found that mechanical ventilation was significantly associated with odds of delirium even after adjustment for sedatives.

   Estimated Time: 27:15 Coronavirus, COVID-19, Therapies, Ventilatory Support

Clinical Pharmacists: An Invaluable Part of the Coronavirus Disease 2019 Frontline Response

From Critical Care Explorations The authors describe how clinical pharmacists fulfilled an essential service during the coronavirus pandemic by working to ensure the best possible outcomes for the patients they served on the frontline.

   Estimated Time: 13:50 Coronavirus, COVID-19

Resolution of Coronavirus Disease 2019 Infection and Pulmonary Pathology With Nebulized DAS181: A Pilot Study

From Critical Care Explorations The authors investigated the safety and effects of nebulized DAS181 on hypoxic coronavirus disease 2019 patients.

   Estimated Time: 15:50 Coronavirus, COVID-19, Therapies

Volatile Isoflurane in Critically Ill Coronavirus Disease 2019 Patients—A Case Series and Systematic Review

From Critical Care Explorations The authors evalute the use of isoflurane in patients with coronavirus disease 2019–induced acute respiratory distress syndrome.

   Estimated Time: 22:23 min ARDS, Coronavirus, COVID-19, Therapies, Ventilatory Support

Almitrine Infusion in Severe Acute Respiratory Syndrome Coronavirus 2-Induced Acute Respiratory Distress Syndrome: A Single-Center Observational Study

From Critical Care Medicine The authors assessed the effect of almitrine, a selective pulmonary vasoconstrictor, on arterial oxygenation in severe acute respiratory syndrome coronavirus 2-induced acute respiratory distress syndrome.

   Estimated Time: 20:07 min ARDS, Coronavirus, COVID-19, Therapies

If a patient reports shortness of breath but has an oxygen saturation of 95%, is this patient a candidate for dexamethasone?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 01:50 min Coronavirus, Corticosteriods, COVID-19, Supportive Care

Have steroids been used after discharge?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 00:59 min Coronavirus, Corticosteriods, COVID-19

After a patient has tested positive for COVID-19, when is the most appropriate time to administer remdesivir to maximize its effectiveness?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.

   Estimated Time: 01:01 min Coronavirus, Corticosteriods, COVID-19

What is your experience with COVID-19 patients and ECMO?

Despite remdesivir, dexamethasone, and twice-daily anticoagulation, a patient’s condition continues to deteriorate. The patient is intubated, and every possible ventilation mode has been tried. The P/F ratio is decreasing, and pressure ventilation is not working. What is your ...

Which medications are used for a hemodynamically unstable intubated patient who is progressing toward or has developed acute respiratory distress syndrome? Are remdesivir or steroids used? What about anticoagulation, given the high risk of thrombosis?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on November 4, 2020.