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Did you manage any acutely ill patients on the ward with noninvasive ventilation and proning? Did you prone nonintubated patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on August 12, 2020.


What are the most common presenting signs and symptoms of COVID-19? What are the more serious signs of a life-threatening situation? What are the indications for ICU admission that non-ICU clinicians must be aware of?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on August 12, 2020.


What is double anticoagulation prophylaxis?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


Are you using typical DVT prophylaxis or something more, such as therapeutic anticoagulation?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


Corticosteroid Responsive Encephalopathy: Prolonged Coma in Patients Late in the Course of Dreadful Severe Acute Respiratory Syndrome Coronavirus 2 Infection

From Critical Care Explorations. In this case report, the authors describe two cases of prolonged coma after weaning off sedation in severe acute respiratory syndrome coronavirus 2 with rapid neurologic improvement shortly after high-dose corticosteroid regimen.


Acute Kidney Injury in Pediatric Inflammatory Multisystem Syndrome Temporally Associated With Severe Acute Respiratory Syndrome Coronavirus-2 Pandemic: Experience From PICUs Across United Kingdom

From Critical Care Medicine. The authors evaluated the prevalence, evolution, and clinical factors associated with acute kidney injury in children admitted to PICUs with pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus-2.


A Hybrid Model of Pediatric and Adult Critical Care During the Coronavirus Disease 2019 Surge: The Experience of Two Tertiary Hospitals in London and New York

From Pediatric Critical Care Medicine. In this report, the authors describe the hybrid model implemented at institutions in New York and London and discuss shared experiences, pitfalls, challenges, and adjustments required in caring for both young and older patients.


Extracorporeal Membrane Oxygenation in Severe Acute Respiratory Distress Syndrome: Possible Late Indication for Coronavirus Disease 2019?

From Critical Care Explorations. In this case report, the authors note that late extracorporeal membrane oxygenation may be considered in selected patients as a bridge to recovery. Further prospective studies are, however, needed.


Timing of Intubation and Its Implications on Outcomes in Critically Ill Patients With Coronavirus Disease 2019 Infection

From Critical Care Explorations. In this Letter to the Editor, the authors report their findings from an observational study aimed to compare the difference in outcomes of critically ill patients with coronavirus disease 2019 who were intubated early versus later in the disease course.


Improving Survival of Critical Care Patients With Coronavirus Disease 2019 in England: A National Cohort Study, March to June 2020

From Critical Care Medicine. The authors measured temporal trends in survival over time in people with severe coronavirus disease 2019 requiring critical care (high dependency unit or ICU) management, and assessed whether temporal variation in mortality was explained by changes in patient demographics and comorbidity burden over time.


SCCM Pod-427 Severe COVID-19 and Sepsis

Severe COVID-19 infection can be a form of viral sepsis with occasionally concomitant bacterial infection.


What is double anticoagulation prophylaxis?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


Are you using typical DVT prophylaxis or something more, such as therapeutic anticoagulation?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


If a patient has had COVID-19 for 3 weeks and is still short of breath and fatigued and has a lot of ground-glass opacities on radiograph, should this patient receive steroids?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


What is your typical medication regimen for COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


What is your center’s approach to supporting another center if it has a COVID-19 patient who may need intubation? What advice do you have for smaller centers that may have a potential COVID-19 patient who needs ventilation?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


What is your perspective on the approach to mechanical ventilation for COVID-19 patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


How do you achieve a balance between staff safety and PPE use and assessing patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


How do emergency department staff identify patients who need critical care? How are these patients triaged, and what criteria are used to determine whether patients are transferred to a ward, to the ICU, or to home?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


What is the approach in the emergency department for patients who arrive with potential COVID-19 symptoms? What triage, diagnostic, and treatment practices are in place?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


What sticks out for you in terms of what has changed going into the second wave of the pandemic? What are some key issues and what should we expect going forward?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on October 14, 2020.


Are you using convalescent plasma in your practice?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


Does literature on the peripheral vascular administration of vasoactive drugs apply to children as well as adults?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


Should dexamethasone or remdesivir be started on a patient who requires oxygen via nasal cannula and is highly suspected of having COVID-19 if test results are still pending?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


What is the time frame for placing vascular catheters in these patients for administration of vasoactive drugs?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


Have you become more aggressive in placing arterial lines in these patients when you might have only monitored pulse oximetry in the past?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


What is the difference between pulse oximetry and arterial oxygen tension

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


How do approaches for children differ from those for adults?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


Are you using steroids, including dexamethasone, in your adult and pediatric practices?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


What is the best way to determine when mechanically ventilated patients should be transitioned to noninvasive ventilation?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


What is the practice in your institution for confusion, dementia, and mobilization in these patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


Which type of nutrition support is most appropriate for severely injured patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


How should anticoagulation be approached in the critically ill patient with COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


How should patients who require mechanical ventilation be identified and how should initial ventilator settings be determined?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on September 9, 2020.


Vitamin Treatment and Renin-Angiotensin System Inhibition in Patients with COVID-19

During this 1-hour activity expert faculty from the American Society of Health-System Pharmacists and the Society of Critical Care Medicine discussed the use of vitamins as adjunctive treatment in patients with COVID-19 as well as the role of Renin-Angiotensin System Inhibition in COVID-19 patients.


Physiologic Response to Angiotensin II Treatment for Coronavirus Disease 2019–Induced Vasodilatory Shock: A Retrospective Matched Cohort Study

From Critical Care Explorations. In this study, the authors found that angiotensin-II treatment for coronavirus disease 2019–induced distributive shock was associated with rapid improvement in multiple physiologic indices and that angiotensin-II in coronavirus disease 2019–induced shock warrants further study.


Extracorporeal Membrane Oxygenation Retrieval in Coronavirus Disease 2019: A Case-Series of 19 Patients Supported at a High-Volume Extracorporeal Membrane Oxygenation Center

From Critical Care Explorations. In this observational study, the authors concluded that extracorporeal membrane oxygenation retrieval can rescue young, previously healthy patients with severe coronavirus disease 2019 in whom all the conventional respiratory measures have failed and found that thrombotic and hemorrhagic complications are frequent in this cohort.


Persevering With Prone Ventilation in Coronavirus Disease 2019 Pneumonia

From Critical Care Explorations. In this case study, the authors present a 53-year-old patient with a severe coronavirus disease 2019 pneumonia who has made a remarkable recovery after a difficult period on intensive care.


Letter to the Editor: Declines in Mortality Over Time for Critically Ill Adults With Coronavirus Disease 2019

From Critical Care Medicine. In this Letter to the Editor, the authors report an update to a previous study, finding a decline in mortality rates in critically ill patients with COVID-19.


Caring for Critically Ill Children With Suspected or Proven Coronavirus Disease 2019 Infection: Recommendations by the Scientific Sections’ Collaborative of the European Society of Pediatric and Neonatal Intensive Care

From Pediatric Critical Care Medicine. In this article, the authors review the current clinical knowledge of coronavirus disease 2019 disease in critically ill children and discuss some specific treatment concepts based mainly on expert opinion based on limited experience and the lack completed controlled trials in children at the time of the paper.


Multisystem Inflammatory Syndrome in Children Associated With Coronavirus Disease 2019 in a Children's Hospital in New York City

From Pediatric Critical Care Medicine. In this article, the authors report their experience developing a clinical inpatient protocol for the evaluation, management, and follow-up of patients with multisystem inflammatory syndrome.


Letter to the Editor: Prevalence and Clinical Correlates of Echo-Estimated Right and Left Heart Filling Pressures in Hospitalized Patients With Coronavirus Disease 2019

From Critical Care Explorations In this Letter to the Editor, the authors discuss their study in which they hypothesized that a significant proportion of coronavirus disease 2019 patients has evidence of pulmonary hypertension associated with elevated left heart filling pressure on transthoracic echocardiography.


Clinical Outcomes Following Tocilizumab Administration in Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this study, the authors examined the outcomes of critically ill coronavirus disease 2019 patients treated with tocilizumab and factors associated with clinical improvement.


The POSITIONED Study: Prone Positioning in Nonventilated Coronavirus Disease 2019 Patients - A Retrospective Analysis

From Critical Care Explorations. In this study, the authors investigated explored whether awake self-proning improved outcomes in coronavirus disease 2019-infected patients treated in a rural medical center with limited resources during a significant local coronavirus disease 2019 outbreak.


Delayed Development of Coronary Artery Dilitation in Suspected Severe Acute Respiratory Syndrome Coronavirus 2 Multisystem Inflammatory Syndrome: More Research Needed

From Critical Care Explorations. In this case report, the authors describe a pediatric patient with coronavirus disease-19-associated multisystem inflammatory syndrome without robust hyperinflammation and a delayed finding of coronary artery dilatation, which they believe highlights the need for further mechanistic understanding of coronavirus disease-19 disease and subsequent multisystem inflammatory syndrome in children or Kawasaki disease development.


Convalescent Plasma Therapy in Four Critically Ill Pediatric Patients With Coronavirus Disease 2019: A Case Series

From Critical Care Explorations. In this case report, the authors report a series of four critically ill pediatric patients with acute respiratory failure who received coronavirus disease 2019 convalescent plasma as a treatment strategy for severe disease.


Antiviral Dosing Modification for Coronavirus Disease 2019–Infected Patients Receiving Extracorporeal Therapy

From Critical Care Explorations. In this study, the authors gathered available published resources including physicochemical and pharmacokinetic properties and suggest antiviral drug dosing adaptation for coronavirus disease 2019–infected critically ill patients receiving extracorporeal therapy.


Three-Dimensional Printed Ventilators: A Rapid Solution to Coronavirus Disease 2019–Induced Supply-Chain Shortages

From Critical Care Explorations. In this paper, the authors report that three-dimensional printed ventilators, such as "CRISIS," propose a potential solution to increase the available number of vents for the United States and abroad, one that is dynamic and able to absorb the massive influx of hospitalized patients for the foreseeable future.


Quantification of Neurological Blood-Based Biomarkers in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations. In this study, the authors sought to provide an objective characterization of acute neurologic injury in critically ill patients with coronavirus disease 2019.


SCCM Pod-423 Coagulopathy in COVID-19 Patients

COVID-19 is associated with a high prevalence of coagulopathy and venous thromboembolism. Host B. Kyle Enfield, MD, FCCM, talks with Jerrold H. Levy, MD, FAHA, FCCM, about what clinicians need to know about this serious problem and how it impacts care delivery (Iba et al. Crit Care Med. 2020;48:1358-1364).


SCCM Pod-422 Procalcitonin in COVID-19 and Influenza-Related Secondary Bacterial Infections

Procalcitonin testing on admission seems to be a valuable piece of information for early risk assessment and ruling out bacterial co-infection in COVID-19 patients.


SCCM Pod-421 COVID-19 and Renal Replacement Therapy

The increase in acute kidney injury in COVID-19 patients is resulting in more utilization of renal replacement therapy (RRT) and continuous renal replacement therapy (CRRT).


COVID-19: What’s Next: A Deeper Dive into Top Sessions

COVID-19: What’s Next, the first-of-its kind virtual conference hosted by the Society of Critical Care Medicine (SCCM), featured the newest research findings, epidemiologic models, and guideline updates for caring for patients with COVID-19 from specialists on the front lines.


The Impact of the Novel Coronavirus on Brazilian PICUs

From Pediatric Critical Care Medicine. The authors evaluated the impact of the coronavirus disease 2019 pandemic, considering the physical distancing and schools closing, on the characteristics of admission and epidemiology on Brazilian PICUs.
 


Treatment for Severe Coronavirus Disease 2019 With the Seraph-100 Microbind Affinity Blood Filter

From Critical Care Explorations. The authors sought to determine whether Seraph-100 (Exthera Medical Corporation, Martinez, CA) treatment provides clinical benefit for severe coronavirus disease 2019 cases that require mechanical ventilation and vasopressor support.


Point-of-Care Lung Ultrasound for Detecting Severe Presentations of Coronavirus Disease 2019 in the Emergency Department: A Retrospective Analysis

From Critical Care Explorations. In this study, lung ultrasound diagnosed severe presentations of coronavirus disease 2019 with similar sensitivity to chest radiograph, CT, and reverse transcriptase-polymerase chain reaction (on first testing) and improved specificity compared to chest radiograph.
 


Letter to the Editor: Weaning by Surgical Tracheostomy and Portable Ventilators Released ICU Ventilators During Coronavirus Disease 2019 Surge in London

From Critical Care Explorations. In this Letter to the Editor from London, the authors share experiences with an integrated model of surgical tracheostomy weaning of respiratory critical care patients by a specialist mobile weaning team, using tracheostomy-licensed ventilators, and noted that it appears safe, effective and may be transferrable to other healthcare systems where ICU resource limitation is a reality during the COVID-19 pandemic.


Mortality Rates in a Diverse Cohort of Mechanically Ventilated Patients With Novel Coronavirus in the Urban Midwest

From Critical Care Explorations. In this study, the authors found mortality rates in mechanically ventilated patients with coronavirus disease 2019 to be lower than some previously reported with longer lengths of stay.
 


Letter to the Editor: Impact of Asynchronies in Acute Respiratory Distress Syndrome Due to Coronavirus Disease 2019

From Critical Care Explorations. In this Letter to the Editor, the authors state that close monitoring of patients with COVID-19 and mechanical ventilation is required; staying at the patient’s bedside is necessary to identify life-threatening asynchronies and must be resolved promptly, as well as finding strategies for prevention of asynchronies. 
 


Letter to the Editor: Tracheostomy for Coronavirus Disease 2019 Patients: Maintaining the Standard of Care

From Critical Care Explorations. In this Letter to the Editor, the authors respond to the new recommendations for delaying tracheostomy for coronavirus disease 2019 patients to day 21 post-intubation to ensure viral clearance.
 


Letter to the Editor: Urinary Neutrophil Gelatinase-Associated Lipocalin in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations. In this Letter to the Editor, the authors report a retrospective analysis of urinary neutrophil gelatinase-associated lipocalin (NGAL) in ICU patients with COVID-19-associated respiratory failure. 
 


Letter to the Editor: The Triage Stalemate During the Coronavirus Disease 2019 Pandemic: Losing Fairness to Ethical Paralysis

From Critical Care Medicine. The authors write in response to an article in Critical Care Medicine by Sprung et al., which outlined the major considerations for ethical ICU triaging under pandemic conditions and discuss the lack of systematic triaging in U.S. health care institutions.
 


Sepsis and Coronavirus Disease 2019: Common Features and Anti-Inflammatory Therapeutic Approaches

From Critical Care Medicine. The authors present some common features shared by severe coronavirus disease 2019 patients and sepsis and describe proposed anti-inflammatory therapies for coronavirus disease 2019 which have been previously evaluated in sepsis.
 


High-Flow Nasal Oxygen in Coronavirus Disease 2019 Patients With Acute Hypoxemic Respiratory Failure: A Multicenter, Retrospective Cohort Study

From Critical Care Medicine. In this study, the authors analyzed the effectiveness of high-flow nasal oxygen treatment and aimed to identify the variables predicting high-flow nasal oxygen treatment failure in coronavirus disease 2019 patients with acute hypoxemic respiratory failure.
 


Prevalence and Impact of Hyponatremia in Patients With Coronavirus Disease 2019 in New York City

From Critical Care Medicine. In this study from New York, NY, the authors found that hyponatremia occurred in nearly a third of coronavirus disease 2019 patients, was an independent predictor of in-hospital mortality, and was associated with increased risk of encephalopathy and mechanical ventilation.
 


Foreword: Does Severe Acute Respiratory Syndrome Coronavirus 2 Cause Sepsis?

From Critical Care Medicine. In this foreword, the authors contend that there should be no debate that SARS-CoV-2 is an important cause of sepsis and that labeling it as such is beneficial and appropriate.


Plasma Exchange: An Effective Rescue Therapy in Critically Ill Patients With Coronavirus Disease 2019 Infection

From Critical Care Medicine. In this single center study, the authors found that plasma exchange mitigates cytokine storm, reverses organ failure, and could improve survival in critically ill patients with coronavirus disease 2019 infection.
 


Novel Outcome Biomarkers Identified With Targeted Proteomic Analyses of Plasma From Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this study, the authors found that targeted proteomics with feature classification easily distinguished both healthy control subjects and coronavirus disease 2019 tested negative ICU patients from coronavirus disease 2019 tested positive ICU patients. Multiple proteins were identified that accurately predicted coronavirus disease 2019 tested positive patient mortality.


Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation

From Critical Care Explorations. The authors found that thrombosis profiling identified endothelial activation and glycocalyx degradation in coronavirus disease 2019 positive patients and believe that the data from this study suggest that medications to protect and/or restore the endothelial glycocalyx, as well as platelet inhibitors, should be considered for further study.


Editorial: Pediatric Sepsis in the Time of Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this editorial, the author reviews ""Perspectives on Pediatric Sepsis in Patients with COVID-19"" from the Surviving Sepsis Campaign Pediatric Guidelines Taskforce authors.
 


Does Pulmonary Aspergillosis Complicate Coronavirus Disease 2019?

From Critical Care Explorations. In this article, the authors summarize what is known about coronavirus disease 2019 complicated by Aspergillus, introduces coronavirus disease 2019–associated pulmonary aspergillosis as a possible clinical entity, and describes reasons clinical suspicion of Aspergillus is warranted in the critical care setting.
 


Dexmedetomidine-Associated Hyperpyrexia in Three Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations. In this study of three patients, the authors state that their findings suggest that high doses of dexmedetomidine infusion are associated with hyperpyrexia in a seemingly dose-dependent fashion in critically ill patients with coronavirus disease 2019.
 


Thromboelastography to Detect Hypercoagulability and Reduced Fibrinolysis in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Patients

From Critical Care Explorations. In this study, the authors investigated thromboelastography in patients with coronavirus disease 2019-associated acute respiratory distress syndrome with the goal of characterizing suspected coagulopathy and impaired fibrinolysis.
 


Disseminated Multifocal Intracerebral Bleeding Events in Three Coronavirus Disease 2019 Patients on Extracorporeal Membrane Oxygenation As Rescue Therapy

From Critical Care Explorations. In this article, the authors describe three coronavirus disease 2019 patients suffering from acute respiratory distress syndrome under venovenous extracorporeal membrane oxygenation therapy and tight anticoagulation monitoring presenting a novel pattern of multifocal brain hemorrhage in various degrees in all cerebral and cerebellar lobes.
 


Letter to the Editor: Transforming a PICU Into an Adult ICU During the Coronavirus Disease 2019 Pandemic: Meeting Multiple Needs

From Critical Care Explorations. In this Letter to the Editor, the authors describe the process converting half of their 40-bed PICU into a negative-pressure biocontainment ICU dedicated to adult coronavirus disease 2019 patients within a 1,003-bed academic quaternary hospital.


Probative Value of the D-Dimer Assay for Diagnosis of Deep Venous Thrombosis in the Coronavirus Disease 2019 Syndrome

From Critical Care Medicine.The authors describe the predictive utility of the D-dimer assay among patients with the coronavirus disease 2019 syndrome for unprovoked lower extremity deep venous thrombosis.


Editorial: Coronavirus Disease 2019 Prediction Modeling: Everything Old Is NEWS Again

From Critical Care Medicine. In this Editorial, the authors comment on the article by Liu et al. “Evaluation of the Risk Prediction Tools for Patients With Coronavirus Disease 2019 in Wuhan, China: A Single-Centered, Retrospective, Observational Study” and note that tools developed for general critical illness can be leveraged for COVID-19 patient care.


Effects of Positive End-Expiratory Pressure in “High Compliance” Severe Acute Respiratory Syndrome Coronavirus 2 Acute Respiratory Distress Syndrome

From Critical Care Medicine. In this study, the authors state their data suggest that a ""higher” positive end-expiratory pressure approach in patients with severe acute respiratory syndrome coronavirus 2 acute respiratory distress syndrome and high compliance improves oxygenation and lung aeration but may result in alveolar hyperinflation and hemodynamic alterations.
 


Placenta-Derived Cell Therapy to Treat Patients With Respiratory Failure Due to Coronavirus Disease 2019

From Critical Care Explorations. The authors sought to determinewhether placental cell therapy PLacental eXpanded (PLX)-PAD (Pluristem Therapeutics, Haifa, Israel) was beneficial to treating critically ill patients suffering from acute respiratory distress syndrome due to coronavirus disease 2019.
 


Tokyo and New York: A Study in the Contrasting Effects of Socioeconomic Status on Coronavirus Disease 2019 Outcomes

From Critical Care Explorations. The authors examined the association between socioeconomic status and the rate of coronavirus disease 2019 infections using public data from Tokyo.


Editorial: Delivering Care From an Unstable Evidence Base: The Evolving Care of Coronavirus Disease 2019 Through the Lens of High-Flow Nasal Oxygen

From Critical Care Medicine. In this Editorial, the authors discuss the challenges of caring for patients with COVID-19 without evidence to guide them through the lens of high-flow nasal oxygenation and how there have been slow changes for improvement.


Guiding Principles for the Conduct of Observational Critical Care Research for Coronavirus Disease 2019 Pandemics and Beyond: The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study Registry

From Critical Care Medicine. In this article, the authors describe how the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study coronavirus disease 2019 registry sought to develop and implement prespecified best practices combined with grassroots efforts from clinical sites worldwide in order to develop clinically useful knowledge in response to a pandemic.
 


Coronavirus Disease 2019 and Acute Respiratory Distress Syndrome: Why the Intensivist Is More Important Than Ever

From Critical Care Medicine. In this Viewpoints article, the authors discuss the challenges of ARDS in COVID-19 patients.


Coronavirus Disease 2019 Acute Respiratory Distress Syndrome: Guideline-Driven Care Should Be Our Natural Reflex

From Critical Care Medicine. In this Viewpoints article, the authors discuss the value of evidence-based, guidelines-driven care in ARDS in patients with COVID-19.
 


The Association of Inflammatory Cytokines in the Pulmonary Pathophysiology of Respiratory Failure in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations. The authors investigated  the pathophysiological relationship between proinflammatory cytokines and respiratory failure in severe coronavirus disease 2019.


Molecular Diagnosis of Coronavirus Disease 2019

From Critical Care Explorations. In this article, the authors review current approaches to the molecular diagnosis of coronavirus disease 2019.


Increased Dead Space Ventilation and Refractory Hypercapnia in Patients With Coronavirus Disease 2019: A Potential Marker of Thrombosis in the Pulmonary Vasculature

From Critical Care Explorations. This case series highlights clinical findings and management of coronavirus disease 2019 patients with refractory hypercapnia despite maximal/optimal ventilatory support.


Subcutaneous Emphysema, Pneumomediastinum, and Pneumothorax in Critically Ill Patients With Coronavirus Disease 2019: A Retrospective Cohort Study

From Critical Care Explorations. In this observational study, the authors describe patients with barotrauma, which appears to be a common complication of severe coronavirus disease 2019. 


Inpatient Mortality According to Level of Respiratory Support Received for Severe Acute Respiratory Syndrome Coronavirus 2 (Coronavirus Disease 2019) Infection: A Prospective Multicenter Study

From Critical Care Explorations. In this study, the authors describe patients according to the maximum degree of respiratory support received and report their inpatient mortality due to coronavirus disease 2019.


Letter to the Editor Treatment of Critically Ill Coronavirus Disease 2019 Patients With Adjunct Therapeutic Plasma Exchange: A Single-Center Retrospective Case Series

From Critical Care Explorations. In this Letter to the Editor, the authors describe their experience with a series of eight patients receiving adjunct therapeutic plasma exchange for severe coronavirus disease pneumonia complicated by sepsis with multiple organ dysfunction in which C-reactive protein and ferritin levels significantly decreased with therapeutic plasma exchange, whereas D-dimer decreased to a lesser degree.


In Silico Modeling of Coronavirus Disease 2019 Acute Respiratory Distress Syndrome: Pathophysiologic Insights and Potential Management Implications

From Critical Care Explorations. In this study, the authors adapted a high-fidelity computational simulator to develop quantitative insights into the key pathophysiologic differences between the coronavirus disease 2019 acute respiratory distress syndrome and the conventional acute respiratory distress syndrome and to assess the impact of different positive end-expiratory pressure, Fio2, and tidal volume settings.


Letter to the Editor: Early Clinical Experience in Using Helmet Continuous Positive Airway Pressure and High-Flow Nasal Cannula in Overweight and Obese Patients With Acute Hypoxemic Respiratory Failure From Coronavirus Disease 2019

From Critical Care Explorations. In this Letter to the Editor, the authors present their retrospective review of COVID-19 patients admitted to the ICUs within two academic urban hospitals (1,012 total hospital beds), comparing helmet continuous positive airway pressure and high-flow nasal cannula in patients with a body mass index greater than or equal to 25 kg/m2 who had persistent hypoxemia.


Concise Critical Appraisal: Dexamethasone Use in the Treatment of COVID-19

This Concise Critical Appraisal offers a look into the results of the RECOVERY trial published in the New England Journal of Medicine, which demonstrated that dexamethasone improved mortality in hospitalized patients with COVID-19.


SCCM Experts Weigh in on Latest COVID-19 Treatment Strategies

This article distills some of the challenges and lessons learned in key areas of COVID-19 management: convalescent plasma therapy and strategies for diabetes/hyperglycemia and myocarditis.


Relocating IV Pumps for Critically Ill Isolated Coronavirus Disease 2019 Patients From Bedside to Outside the Patient Room

From Critical Care Explorations. The authors discuss advantages and disadvantages of relocating IV pumps for coronavirus disease 2019 patients from bedside to outside the patient room and characterize reproducible details of an external infusion pump model.


Evaluation of Coronavirus Disease 2019 Severity Using Urine Biomarkers

From Critical Care Explorations. The authors conducted a study to determine whether noninvasive urine biomarkers can predict the clinical severity of coronavirus disease 2019.


Editorial: Coronavirus Disease 2019: A Tsunami of Data and a Plethora of Unanswered Questions

From Pediatric Critical Care Medicine. In this editorial, the author discusses issues emerging from the study by Bhumbra et al. (Clinical features of critical coronavirus disease 2019 in children) that are worthy of discussion and further exploration, including the predilection for racial minorities, similarities and differences to sepsis, wide expression of clinical disease, and the conundrum of providing family centered care.


Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the Era of Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this article, the authors discuss the Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-associated Organ Dysfunction in Children as they relate to COVID-19.


Critical Care for Coronavirus Disease 2019: Perspectives From the PICU to the Medical ICU

From Critical Care Medicine. The authors describe the unique perspective of pediatric intensivists caring for critically ill adults during the coronavirus disease 2019 pandemic.


Letter to Editor: In Response to "Coagulopathy of Coronavirus Disease 2019"

From Critical Care Medicine. This Letter to the Editor is in response to the article "Coagulopathy of Coronavirus 2019" by Iba et a.


Obesity and the Risk of Intubation or Death in Patients With Coronavirus Disease 2019

From Critical Care Medicine. In the study, obesity was an independent risk factor for intubation or death.


Evaluation of the Risk Prediction Tools for Patients With Coronavirus Disease 2019 in Wuhan, China: A Single-Centered, Retrospective, Observational Study

From Critical Care Medicine. In this study from China, the authors evaluated and compared the efficacy of National Early Warning Score, National Early Warning Score 2, Rapid Emergency Medicine Score, Confusion, Respiratory rate, Blood pressure, Age 65 score, and quick Sepsis-related Organ Failure Assessment on predicting in-hospital death in patients with coronavirus disease 2019.


Higher Intensity Thromboprophylaxis Regimens and Pulmonary Embolism in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Medicine. In this study from Belgium, the authors assessed the role of thromboprophylaxis regimens on the occurrence of pulmonary embolism in coronavirus disease 2019 patients.


Role for Anti-Cytokine Therapies in Severe Coronavirus Disease 2019

From Critical Care Explorations. In this narrative review, the authors summarize existing knowledge of the immune response to coronavirus infection and highlight the current and potential future roles of therapeutic strategies to combat the hyperinflammatory response of patients with coronavirus disease 2019.


Nationwide Incidence and Outcomes of Patients With Coronavirus Disease 2019 Requiring Intensive Care in Iceland

From Critical Care Medicine. In this study from Iceland, which had early adoption of widespread testing, the authors report a lower overall ratio of ICU admissions for coronavirus disease 2019 among severe acute respiratory syndrome coronavirus 2 positive patients and a lower hospital mortality for patients treated in the ICU for coronavirus disease 2019 compared with initial reports from Italy and China.


Principles Guiding Nonpandemic Critical Care Research During a Pandemic

From Critical Care Medicine. In this article, the authors describe the importance of critical care clinical research that is not pandemic-focused during pandemic times; outline principles to assist in the prioritization of nonpandemic research during pandemic times; and propose a guiding framework for decisions about whether, when and how to continue nonpandemic research while still honoring the moral and scientific imperative to launch research that is pandemic-focused.


Letter to the Editor: Concerns About the Timing and Settings of Initiating Extracorporeal Membrane Oxygenation in Patients With Severe Coronavirus Disease 2019 Pneumonia

From Critical Care Medicine. In this Letter to the Editor, the author respond to an article by Yang et al about COVID and ECMO.


Intracranial Pressure Dynamics and Cerebral Vasomotor Reactivity in Coronavirus Disease 2019 Patient With Acute Encephalitis

From Critical Care Explorations. In this article, the authors describe the intracranial pressure dynamics and cerebral vasomotor reactivity in a coronavirus disease 2019 patient with acute encephalitis treated with cerebrospinal fluid drainage and therapeutic plasma exchange.


Myoclonus in Patients With Coronavirus Disease 2019: A Multicenter Case Series

From Critical Care Medicine. The authors describe the risk factors for and outcomes after myoclonus in a cohort of patients with coronavirus disease 2019.


Core Outcomes Set for Trials in People With Coronavirus Disease 2019

From Critical Care Medicine. The authors aimed to establish a core outcomes set for trials in people with suspected or confirmed coronavirus disease 2019.


International Survey to Establish Prioritized Outcomes for Trials in People With Coronavirus Disease 2019

From Critical Care Medicine. The author set out to generate a consensus-based, prioritized list of outcomes for coronavirus disease 2019 trials.


Timing of Intubation and Mortality Among Critically Ill Coronavirus Disease 2019 Patients: A Single-Center Cohort Study

From Critical Care Medicine. The authors examined the impact of time to intubation and use of high-flow nasal cannula on clinical outcomes in patients with coronavirus disease 2019.


Coronavirus Disease 2019 Intermediate Care Units: Containing Escalation of ICUs

From Critical Care Medicine. In this Letter to the Editor, the authors share their view that - for COVID-19 patient - Intermediate Care Units (IMCUs) may be better suited for post-ICU care than ordinary hospital wards.


Renin-Angiotensin System and COVID-19

This presentation is a review of the renin-angiostensin System and COVID-19. This is SCCM curated COVID-19 microlearning content.


COVID-19 Pharmacology Debates: Management of Delirium, Pain and Sedation

The Society of Critical Care Medicine (SCCM) and the American Society of Health-System Pharmacists (ASHP) in their third series of therapeutic debates in the management of COVID-19.


COVID-19 Pharmacology Debates: Steroid and Antiviral Use in COVID-19 Patients

ASHP and the SCCM teamed up in their second series of therapeutic debates in the management of COVID-19. In the first debate, the content matter experts reviewed the latest literature and debate the use of steroids for treatment of COVID-19.


EEG Changes Associated with COVID-19

An expert panel representing the Society of Critical Care Medicine (SCCM) and the Neurocritical Care Society (NCS) teamed up to discuss cEEG monitoring and implementation of a cEEG program in COVID-19 patients, seizure detection, utility and treatment implications, along with practical considerations.


ICU vs. PICU Liberation: Same Goals, Different Tools

This presentation discusses the difference in ICU and PICU liberation to implement the ICU Liberation Bundle in patients with COVID-19. This is SCCM curated COVID-19 microlearning content.


Incidence of Venous Thromboembolism in Critically Ill Coronavirus Disease 2019 Patients Receiving Prophylactic Anticoagulation

From Critical Care Medicine. Deep venous thrombosis is very common in critically ill patients with coronavirus disease 2019, so the authors describe the prevalence of venous thromboembolism in critically ill patients receiving different regimens of prophylactic anticoagulation.


Letter to the Editor: Barrier Techniques to Reduce Aerosolization During Extubation

From Critical Care Explorations. The authors describe a barrier technique during extubation which contained aerosolized particulates into a non-rebreather mask at time of extubation. The authors believe their protocol allows providers to perform extubations while minimizing exposure to aerosolized particles.


Letter to the Editor: Barrier Techniques to Reduce Aerosolization During Cardiopulmonary Resuscitation

From Critical Care Explorations. The authors developed additional modifications to the suggested guidelines to further protect providers from unnecessary aerosolization; it illustrates a sample protocol for provider safety during advanced cardiovascular life support in the coronavirus pandemic.


Editorial: Extracorporeal Membrane Oxygenation During the Coronavirus Disease 2019 Pandemic

From Critical Care Medicine. In this editorial, the authors discuss the important role of extracorporeal membrane oxygenation as a rescue therapy for patients with SARS-CoV-2 pneumonia associated with severe ARDS.


Thromboelastography Profiles of Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Medicine. The authors reviewed thromboelastography studies in critically ill patients with coronavirus disease 2019 to characterize their coagulation states.


Letter to the Editor: Coronavirus Disease 2019: Understanding Immunopathogenesis Is the “Holy Grail” to Explain Why Children Have Less Severe Acute Disease

From Pediatric Critical Care Medicine. In this letter to the editor, the authors state that the understanding of the immunopathogenesis of SARS-CoV-2 infection is important not only to understand the epidemiologic and age-related differences in COVID-19, but it is critical for the identification of appropriate treatment, as well as for the development of a highly immunogenic vaccine with low risk of antibody dependent enhancement.


Pediatric Resuscitation Practices During the Coronavirus Disease 2019 Pandemic

From Pediatric Critical Care Medicine. The authors conducted a survey and found that most U.S. pediatric institutions rapidly adapted their resuscitation systems and practices in response to the coronavirus disease 2019 pandemic.


Coronavirus Disease 2019 Pandemic Measures: Reports From a National Survey of 9,120 ICU Clinicians

From Critical Care Medicine. In this national ICU clinician survey, it was found that there are continued concerns regarding personal protective equipment supplies with the chief issue being N95 respirator availability.


Clinical Features of Critical Coronavirus Disease 2019 in Children

From Pediatric Critical Care Medicine. In this study, the authors observed a greater proportion of hospitalized children requiring mechanical ventilation than has been reported to date; they state that older children, African-American or Hispanic children, and males may be at greater risk for severe illness requiring hospitalization.


Venous Thromboembolism Events Following Venovenous Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Syndrome Coronavirus 2 Based on CT Scans

From Critical Care Medicine. The authors report a 100% occurrence of venous thromboembolism in critically ill patients supported by venovenous extracorporeal membrane oxygenation for severe acute respiratory syndrome coronavirus 2-related acute respiratory distress syndrome using CT scan imaging despite a high target and close monitoring of anticoagulation.


The Impact of Coronavirus Disease 2019 Pandemic on U.S. and Canadian PICUs

From Pediatric Critical Care Medicine. This study found that patients with coronavirus disease 2019 have a high frequency of comorbidities, require longer stays, more ventilatory support than usual PICU admissions, suggesting several avenues for further exploration.


Letter to the Editor: Optimizing the Risk-Benefit Balance of Thromboprophylaxis in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Medicine. This Letter to the Editor is in response to an article by Iba et al. (Coagulopathy of Coronavirus Disease 2019) and discusses dosing recommendations of low molecular weight heparin.


Editorial: Lessons Learned From the Front Line: Outcomes of Noninvasive Ventilation for Coronavirus Disease 2019 Pneumonia in China

From Critical Care Medicine. In this Editorial, the authors look at the study by Wang et al. (Clinical Features of Coronavirus Disease 2019 Patients With Mechanical Ventilation: A Nationwide Study in China)


Editorial: Financial Toxicity After Hospitalization; Considerations in Coronavirus Disease 2019 Recovery

rom Critical Care Medicine. In this Editorial, the authors comment on an article by Hauschildt et al. (Financial Toxicity After Acute Respiratory Distress Syndrome: A National Qualitative Cohort Study).


Leveraging Tele-Critical Care Capabilities for Clinical Trial Consent

From Critical Care Explorations. In this article, the authors share their experience with a patient with severe COVID-19 who was admitted to a clinical trial of an investigational COVID-19 therapeutic using video-telecommunication to obtain informed consent.


Procedures for COVID-19 Cohort Units: Building an Operating Room in a COVID-19 Cohort ICU

This presentation provides procedures for building COVID-19 cohort units. This is SCCM curated COVID-19 microlearning content.


Approaching delirium in patients with COVID-19

This presentation provides an overview of the types of strategies for approaching the D Element (Delirium) of the ICU Liberation Bundle in patients with COVID-19. This is SCCM curated COVID-19 microlearning content.


Letter to the Editor: Thromboprophylaxis in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this Letter to the Editor, the authors report their adapted thromboprophylaxis practice of low-molecular-weight heparin administration in coronavirus disease 2019 ICU patients.


Preparedness and Reorganization of Care for Coronavirus Disease 2019 Patients in a Swiss ICU: Characteristics and Outcomes of 129 Patients

From Critical Care Explorations. The authors report their experience in Switzerland with regard to ICU organization and anticipation, as well as patient characteristics, treatment, and outcomes.


PPE Strategies for the COVID-19 Era

The supply of personal protective equipment (PPE) has been uncertain since the start of the COVID-19 pandemic. Months into this healthcare crisis, supply chains are unpredictable as reports of shortages continue. Follow these key strategies for managing PPE.


Alternative Analgesic and Sedative Agents in the Setting of Drug Shortages during the COVID19 Pandemic

This resources detail how to manage drug shortages for alternative analgesics and sedagent agents. This is SCCM curated COVID-19 microlearning content.


Critical Illness, Intensive Care, And Post-Traumatic Stress Disorder

This resource is a patient guide detailing how Post-Traumatic Stress Disorder (PTSD) is seen in critical illness and intensive care. This is a community developed COVID-19 microlearning resource.


How to Maintain Wellness in the COVID-19 Era

Intensive care unit (ICU) clinicians tend to pride themselves on their ability to care for others, even if it is at the expense of taking care of themselves. Some think of this mantra of "others before me" as a badge of honor, according to James C. Jackson, PhD, PsyD, research professor and assistant director of the ICU Recovery Center at Vanderbilt University Medical Center. Dr. Jackson has a strong message to these clinicians: Now is not the time to dismiss your own needs.


What is your advice for medical, nursing, and advanced practice provider students who want to continue learning and seeking out opportunities but who are barred from patient care because of the risk of transmission or lack of PPE?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


Does your hospital use any inflammatory markers besides D-dimer? Would you advocate for any other inflammatory marker? Do you check D-dimer or other markers on admission, daily, or weekly? What is your rationale for your approach?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


How often do you see COVID-19-induced neuropathy in your patient population? How are you treating it?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


What training was provided to nurses and advanced practice providers in your institution on proning and other COVID-19-related issues?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


What specific skills do non-ICU practitioners need to care for this patient population?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


Are there any differences in standards of care between adult patients and pediatric or adolescent patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


What data support the use of convalescent plasma? Do you have experience with it? Which patients should be treated with it?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


Can you give an update on the current literature on using steroids in the treatment of COVID-19? How are you using this literature in your practice?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


Which patients should be treated with remdesivir and when should it be initiated?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


What are the options for diagnosis, workup, and treatment for a hypercoagulable state?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.


SCCM Pod-418 COVID-19 Learning: Conversion of a Children's Hospital to an Adult Hospital

Montefiore Medical Center in the Bronx, New York, USA, quickly converted a children's hospital to an adult COVID-19 hospital. Hear Margaret M. Parker, MD, MCCM, talk with H. Michael Ushay, MD, PhD, FAAP, FCCM, about the process, challenges with staffing and personal protective equipment, and more.


SCCM Pod-417 COVID-19-Associated Acute Respiratory Distress Syndrome

Clinicians are working to understand and formulate an effective treatment for COVID-19-associated acute respiratory distress syndrome (Marini J. Crit Care Med. 2020 May 13; Epub ahead of print).


Configuring ICUs in the COVID-19 Era

This report provides guidance on how to innovate your existing intensive care unit (ICU) or convert other spaces into an ICU to improve workflow, manage capacity, and minimize healthcare professionals’ exposure to COVID-19 based on the evolving experiences from more than a dozen hospitals and their healthcare professionals on the front lines.


Using Social Media for Rapid Information Dissemination in a Pandemic: #PedsICU and Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this report, the authors describe the use and impact of a targeted strategy for international collaboration and rapid information dissemination on Twitter among members of the pediatric critical care community during a global pandemic.


Online Letter to the Editor: Bronchiolitis and Potential Pathophysiological Implications in Coronavirus Disease 2019 ARDS Patients With Near-Normal Respiratory Compliance

From Critical Care Medicine. The authors share the following opinions on the recruitment-response COVID-19 ARDS patients, 1) bronchiolitis, in a histologic context, is a plausible pathophysiological mechanism, and 2) a simple bedside physiologic test could potentially determine recruitment potential in resource-limited settings.


Online Letter to the Editor: Coronavirus Disease 2019: Withdrawing Mechanical Ventilation to Reallocate Life Support Under Crisis Standards of Care-Nonequivalence of the Equivalence Thesis

From Critical Care Medicine. The authors look at Sprung et al. article ("Adult ICU Triage During the Coronavirus Disease 2019 Pandemic: Who Will Live and Who Will Die? Recommendations to Improve Survival" and the question: Is it ever ethical to remove a ventilator from a patient in order to reallocate it to another we believe would derive more benefit from it?


Pandemic-Related Submissions: The Challenge of Discerning Signal Amidst Noise

From Critical Care Medicine. The editors of Critical Care Medicine discuss the challenge during current pandemic of discerning data from anecdote, information from observation, and ultimately signal amidst noise.


Strategies to Optimize ICU Liberation (A to F) Bundle Performance in Critically Ill Adults With Coronavirus Disease 2019

From Critical Care Explorations. The combination of a novel disease, resource limitations, and risks to medical personnel health have created new barriers to implementing the ABCDEF Bundle, a proven ICU care approach that reduces delirium, shortens mechanical ventilation duration, prevents post-ICU syndrome, and reduces healthcare costs.


Consideration of Severe Coronavirus Disease 2019 As Viral Sepsis and Potential Use of Immune Checkpoint Inhibitors

From Critical Care Explorations. Supportive treatment and immunomodulators have a critical place in the treatment of severe patients until effective antivirals are developed. Interleukin-6 antagonists, one of the immunomodulating agents, appears to be effective in the treatment of cytokine storm, but some patients continue to have severe lymphopenia and immunosuppression.


Statewide Real-Time Tracking of Beds and Ventilators During Coronavirus Disease 2019 and Beyond

From Critical Care Explorations. This brief report describes the rapid deployment of a real-time electronic tracking board for all hospitals in the state of Oregon.


Case Report: Acute Limb Ischemia Due to Arterial Thrombosis Associated With Coronavirus Disease 2019

From Critical Care Explorations. The authors report a case of peripheral arterial thrombosis associated with COVID-19, resulting in acute limb ischemia of the right lower extremity.


Coronavirus Disease 2019: Harnessing Healthy Fear via Knowledge, Attitudes, and Behavior

From Critical Care Explorations. This commentary discussed how fear (both rational and irrational) influences application of evidence-based data in the ICU during pandemics.


Letter to the Editor: Ultrasound Teleguidance to Reduce Healthcare Worker Exposure to Coronavirus Disease 2019

From Critical Care Explorations. The authors illustrate a proof of concept application of teleguidance to ultrasound-guided bedside procedures as an example of an innovative solution that has been used at their institution to maximize patient and provider safety in the COVID-19 era.


Pediatric Critical Care Medicine in the COVID-19 Pandemic

From Pediatric Critical Care Medicine. A foreword from the editors of PCCM about COVID-19 and the journal.


Mechanical Ventilation During the Coronavirus Disease 2019 Pandemic: Combating the Tsunami of Misinformation From Mainstream and Social Media

From Critical Care Medicine. The editorial authors discuss the role of mainstream and social media in creating the narrative that intubation and mechanical ventilation were "the cause of suboptimal outcomes" for critically ill COVID-19 patients, without accounting for hospital staffing and equipment shortages.


Paved With Good Intentions: Hospital Visitation Restrictions in the Age of Coronavirus Disease 2019

From Pediatric Critical Care Medicine. Using their experience in a pediatric intensive care unit, the authors surveyed the shortcomings of current visitation restrictions.


Simulation: Keeping Pace With Pandemics

From Pediatric Critical Care Medicine. The authors discuss the immediate need to become quickly prepared for overwhelming patient care and health system needs, and the usefulness of simulation.


Adult Extracorporeal Membrane Oxygenation Patient Selection During Coronavirus Disease 2019: The Value of a Review Panel During Coronavirus Disease 2019

From Critical Care Medicine. Authors write regarding article by Bohman et al "Approach to Adult Extracorporeal Membrane Oxygenation Patient Selection" and note that a formal approach to decision making is key for the appropriate use of this labori ntensive rescue therapy.


The Combination of Tocilizumab and Methylprednisolone Along With Initial Lung Recruitment Strategy in Coronavirus Disease 2019 Patients Requiring Mechanical Ventilation: A Series of 21 Consecutive Cases

From Critical Care Explorations. This articles describes the outcomes with use of a combination of tocilizumab and 34 methylprednisolone administered around the time of endotracheal intubation in patients with 35 confirmed COVID-19-associated hypoxemic respiratory failure requiring mechanical ventilation.


Review of Viral Testing (Polymerase Chain Reaction) and Antibody/Serology Testing for Severe Acute Respiratory Syndrome-Coronavirus-2 for the Intensivist

From Critical Care Explorations. As the SARS-CoV-2 pandemic develops, assays to detect the virus and infection caused by it are needed for diagnosis and management. In this article, the authors describe to clinicians how each assay is performed, what each assay detects, and the benefits and limitations of each assay.


Design for Implementation of a System-Level ICU Pandemic Surge Staffing Plan

From Critical Care Explorations. The authors provide a description of the design, dissemination, and implementation of an ICU surge provider staffing algorithm, focusing on physicians, advanced practice providers, and certified registered nurse anesthetists, at a system-wide level.


Letter to the Editor: Corticosteroid Administration Is Associated With Improved Outcome in Patients With Severe Acute Respiratory Syndrome Coronavirus 2-Related Acute Respiratory Distress Syndrome

From Criticial Care Explorations. The authors report on the use of corticosteroids in mechanically ventilated patients with SARSCoV-2 related acute respiratory distress syndrome.


Letter to the Editor: Factors Associated With Pulmonary Embolism Among Coronavirus Disease 2019 Acute Respiratory Distress Syndrome

From Critical Care Explorations. To do better understand the risk factors associated with pulmonary embolism in patients with COVID-19, the authors performed a post hoc analysis from the COVADIS project, a multicenter observational study gathering 21 ICUs from France and Belgium.


Gender Difference Is Associated With Severity of Coronavirus Disease 2019 Infection: An Insight From a Meta-Analysis

From Critical Care Explorations. This review article investigates how gender difference can affect the disease severity of COVID-19 infection.


Inflammation Profiling of Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Explorations The authors profiled plasma inflammatory analytes to help understand the host response to COVID19.


Clinical Features of Coronavirus Disease 2019 Patients With Mechanical Ventilation: A Nationwide Study in China

From Critical Care Medicine. Mechanical ventilation (MV) is life-saving for respiratory distress; this study was designed to delineate the clinical features of the COVID-19 patients with MV from a national cohort in China.


How can patients be weaned off high doses of multiple sedatives to which they have become tolerant?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues.

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed.

Webcast held on June 19, 2020


How would you describe the overall big picture of oxygen therapies?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020


Which is better for anticoagulation in hospitalized non-ICU patients: low-molecular-weight heparin or oral anticoagulants?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020


What are the differences between disseminated intravascular coagulation and coagulopathy in COVID-19 patients?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020


What can be done for a critically ill patient with multiorgan dysfunction who is in the ICU on maximum support?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020


What has been the experience with enteral nutrition in COVID-19 patients? Are there any recommendations or practical problems around enteral nutrition, including proning?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues.

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed.

Webcast held on June 19, 2020


What is the optimal timing of prone positioning? Do some patients transition from proning to extracorporeal membrane oxygenation?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020


What is the role of steroids in COVID-19 patients? When should steroids be administered?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020


What has been the experience with extracorporeal membrane oxygenation in COVID-19 patients? What are some of the challenges? How have outcomes been affected?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020


Falls: Non-ICU Emergency Cards

This resource details how manage falls of COVID-19 patients. This is SCCM curated COVID-19 microlearning content.


Altered Mental Status: Non-ICU Emergency Cards

This resource details how to assess the altered mental status of COVID-19 patients. This is SCCM curated COVID-19 microlearning content.


Does any laboratory marker correlate well with or predict severity of illness for COVID-19 patients?

In this question and answer webcast, attendees had the opportunity to post questions about managing critically ill patients with COVID-19 and other issues. Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were also addressed. Webcast held on June 19, 2020


Do you use proning beds or manual proning?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.


What are the benefits of delaying intubation in COVID-19 patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.


Is there concern about an increase in post-intensive care syndrome because of the limitations enacted to keep people safe from COVID-19?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.


What is your opinion about treating patients with COVID-19 and pulmonary disease by limiting fluid volume, similar to treatment of lung transplant patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.


What is the prevalence of the Kawasaki-like severe multiple inflammatory syndrome in children aged 4 to 6 years old with COVID-19 versus in the general population?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.


How effective are medications that target interleukin-6?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.


How were non-ICU nurses brought up to speed to care for patients that overflowed from the ICU?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.


In the first phase of the COVID-19 pandemic, when pediatric ICUs were turned into medical ICUs, how did the pediatric intensive care community manage adult patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.


What is new in the treatment of acute respiratory distress syndrome in COVID-19 patients?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on June 10th, 2020.


Critical Care for Non-ICU Clinicians: Expert Panel Series

This webcast series engages a panel of critical care experts who will address questions from non-ICU clinicians caring for critically ill patients during the COVID-19 pandemic. Participants are encouraged to ask about any related topics at the time of registration or live during the session.


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