Adult Surviving Sepis Campaign Guidelines (Hour-1 Bundle) Children's Surviving Sepsis Campaign Guidelines
Adult ICU Liberation Guidelines and Bundle (A-F) Management of Adults with COVID-19
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BioFire® FilmArray® is the latest in technologies for rapidly identifying pathogens that cause Lower Respiratory Tract Infections (LRTI). Host Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by Tufik Assad M.D., M.S.C.I. to discuss how this technology can be integrated into clinical care to improve patient outcomes, describe the benefits in diagnosing bacterial secondary infections in patients with COVID-19 and summarize the benefits of Pneumonia (PN) Panel in the fight against Antimicrobial Resistance. Dr. Assad is the Medical Director of the Lung Nodule Clinic at Williamson Medical Center. This podcast is sponsored by BioFire. Tufik Assad M.D., M.S.C.I., is the Medical Director of the Lung Nodule Clinic at Williamson Medical Center. Dr. Assad is board certified in Pulmonary Medicine, Critical Care Medicine and Internal Medicine. He practices with Williamson Medical Group in Franklin and is a credentialed physician with Williamson Medical Center.
As a proof of concept, a recurrent neural network (RNN) model was developed using electronic medical record (EMR) data capable of continuously assessing a child’s risk of mortality throughout an ICU stay as a proxy measure of illness severity. Host Margaret M. Parker, MD, MCCM, is joined by Melissa D. Aczon, PhD, to discuss how the RNN model can process hundreds of input variables contained in a patient’s EMR and integrate them dynamically as measurements become available. The RNN’s high discrimination suggests its potential to provide an accurate, continuous, and real-time assessment of a child in the PICU. (Aczon M, et al. Ped Crit Care Med. 2021;22:519-529) Dr. Aczon is a principal data scientist at Children’s Hospital Los Angeles. Melissa D. Aczon, PhD is a Principal Data Scientist at Children’s Hospital Los Angeles.
Learn about the importance of utilizing dynamic assessments of fluid responsiveness to guide treatment in patients with viral sepsis, including COVID-19, and understand how they can be used to help improve patient outcomes in sepsis patients. Host Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by Patrick Troy, MD, to discuss how only 50% of hemodynamically unstable patients are fluid responsive and that the same treatment paradigm in fluid management applies to both viral sepsis and COVID-19 patients (Douglas IS, et al. Chest. 2020;158:1431-1445; Latham H, et al. J Crit Care. 2017;42:42-46). This podcast is sponsored by Baxter. Patrick Troy M.D., is the Division Director Pulmonary Critical Care and Sleep Medicine Physician at Hartford Hospital, Assistant Professor of Clinical Medicine at the University of Connecticut School of Medicine.
Two previously published trials (ARDS et Curarisation Systematique [ACURASYS] and Reevaluation of Systemic Early Neuromuscular Blockade [ROSE]) presented equivocal evidence on the effect of neuromuscular blocking agent infusions in patients with acute respiratory distress syndrome. Host Kyle B. Enfield, MD, FCCM, is joined by Matthias Eikermann, MD, to discuss the different sedation regimens between these two trials as well as the different regimens within the ROSE trial between treatment and control groups. They will also discuss the hypothesis that the proportion of deeper sedation is a mediator of the effect of neuromuscular blocking agent infusions on mortality (Wongtangman K, et al. Crit Care Med. 2021;49:1137-1148; Jabaley C, Crit Care Med. 2021;49:1211-1213). Dr. Eikermann is a professor of anesthesia at Harvard Medical School and an attending anesthesiologist and vice chair of faculty affairs in the Department of Anesthesia, Critical Care and Pain Medicine at Beth Israel Deaconess Medical Center. This podcast is sponsored by Sound Physicians.
Rapid delivery of antibiotics is a cornerstone of sepsis therapy, although time targets for specific components of antibiotic delivery are unknown. Host Ludwig H. Lin, MD, is joined by Stephanie Parks Taylor, MD, to discuss the significance of time lead for suspected sepsis patients, how to use a generous time window wisely, and new and reconfigured technologies opportunities (Taylor SP, et al. Crit Care Med. 2021 May;49:741-747).
Dr. Taylor is an associate professor in the Department of Internal Medicine at Atrium Health’s Carolinas Medical Center in Charlotte, North Carolina, USA. This podcast is sponsored by Biofire.
The prevalence and consequences of dyssynchronies are largely underestimated due to frequent lack of monitoring. Dedicated software solutions are needed to continuously and automatically detect dyssynchronies, which will allow for both clinical research and application aimed at determining the effects of dyssynchronies and their incidence among critically ill patients. Host Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by Laurent Brochard, MD, to explore the different mechanisms of the various patient-ventilator dyssynchronies and how to detect these dyssynchronies and evaluate their possible impact on patient-centered outcomes. Dr. Brochard is inter-department division director of critical care at the University of Toronto in Toronto, Ontario, Canada. This podcast is supported by an unrestricted education grant from Medtronic.
Enteral feed intolerance occurs frequently during enteral nutrition delivery in the critically ill and is associated with lower enteral nutrition delivery and worse clinical outcomes. Host Ludwig H. Lin, MD, is joined by Daren K. Heyland, MD, MSc, FRCPC, to discuss the incidence of enteral feed intolerance, identify factors associated with enteral feed intolerance, and assess the relationship between enteral feed intolerance and key nutritional and clinical outcomes in critically ill patients (Heyland D, et al. Crit Care Med. 2021 Jan;49:49-49). Dr. Heyland is director of the clinical evaluation research unity at Kingston General Hospital and professor in the department of critical care medicine at Queen’s University School of Medicine in Kingston, Ontario, Canada. This podcast is sponsored by Biofire.
Targets for treatment of raised intracranial pressure or decreased cerebral perfusion pressure in pediatric neurocritical care are not well defined. Host Margaret Parker, MD, MCCM, is joined by Alicia K. Au, MD, MS, to discuss the process of defining intracranial pressure and cerebral perfusion pressure thresholds associated with in-hospital mortality across a large single-center pediatric neurocritical care cohort (Au A, et al. Pediatr Crit Care Med. 2021 Feb;22:135-146). Dr. Au is assistant professor of critical care medicine and associate medical director of the pediatric intensive care unit at the University of Pittsburgh Medical Center in Pittsburgh, Pennsylvania.
COVID-19 complicated critical care clinicians’ decision-making with regard to tracheostomy. ICU resource constraints and risk of staff exposure during an aerosol-generating procedure necessitated rapid adaption of clinical practice in the setting of many unknowns. Host Pamela M. Peeke, MD, MPH, FACP, FACSM, is joined by Joshua H. Atkins, MD, PhD; Christopher Rassekh, MD; and Ara Chalian, MD, to discuss essential considerations for tracheostomy in the COVID-19 setting and identify challenges to coordinated development of tracheostomy best practices. This episode’s guests are from the University of Pennsylvania Medical Center in Philadelphia, Pennsylvania, USA. Dr. Atkins is an anesthesiologist and Drs. Rassekh and Chalian are ENT surgeons. This podcast is supported by an unrestricted education grant from Medtronic.