SCCM Pod-418 COVID-19 Learning: Conversion of a Children’s Hospital to an Adult Hospital

SCCM Pod-429 Drug Dosing Considerations in AKI and RRT
Continuous renal replacement therapy (CRRT) is complex, and dosing varies among institutions. Host Michael Smith, MD, is joined by Melissa L. Thompson Bastin, PharmD, BS, BCPS, to review dosing regimens for CRRT, studies of CRRT antibiotic dosing, and CRRT utilization in COVID-19 patients. Dr. Thompson Bastin is a medical ICU and pulmonary critical care pharmacist and assistant adjunct professor at the University of Kentucky in Lexington, Kentucky, USA. This podcast is sponsored by Baxter Healthcare. Published: 12/2/2020

SCCM Pod-428 Endotracheal Tube Size and Aspiration
Each year, approximately 790,000 patients in the United States develop acute respiratory failure that requires intubation and mechanical ventilation. Host Ludwig H. Lin, MD, is joined by Gintas P. Krisciunas, MPH, MA, to explore whether a modifiable risk factor, endotracheal tube size, is associated with the diagnosis of postextubation aspiration in survivors of acute respiratory failure (Krisciunas G et al. Crit Care Med. 2020;48:1604-1611). Gintas P. Krisciunas is a research assistant professor of otolaryngology at Boston University School of Medicine and Boston Medical Center in Boston, Massachusetts, USA. Published: 11/19/2020

SCCM Pod-427 Severe COVID-19 and Sepsis

Severe COVID-19 infection can be a form of viral sepsis with occasionally concomitant bacterial infection. Pamela M. Peeke MD, MPH, FACP, FACSM, is joined by Russell Miller, MD, MPH, FCCM, to discuss the definition of sepsis and overlap with case descriptions of patients with severe COVID-19, how experience with viral sepsis can be leveraged to diagnose and treat COVID-19 patients being admitted to ICU, and the need to be able to differentiate viral from bacterial sepsis to avoid over or under treatment. Dr. Miller is medical director of critical care at FirstHealth of the Carolinas in Pinehurst, North Carolina, USA. This podcast is sponsored by Immunexpress.

Published: 11/10/2020

SCCM Pod-426 CRRT in the ICU From a Nursing Perspective
Continuous renal replacement therapy (CRRT) requires considerable involvement from the bedside nurse. Host Michael Smith, MD, is joined by Barbara McLean, MN, RN, CCNS-BC, NP-BC, CCRN, FCCM, to explore when to start CRRT, the nursing role, and other considerations and challenges. Barbara McLean is a critical care clinical nurse specialist at Grady Health System in Atlanta, Georgia, USA. This podcast is sponsored by Baxter Healthcare. Published: 10/22/2020

SCCM Pod-425 Outcomes in Cystic Fibrosis PICU Admissions
Cystic fibrosis patient care has advanced greatly in recent years and the mortality rate has improved. Host Margaret M. Parker, MD, MCCM, talks with Michael A. Smith, MD, about PICU mortality and the factors associated with death among critically ill children with cystic fibrosis (Smith M, et al. Pediatr Crit Care Med. 2020 Oct;21:e879-887). Dr. Smith is in a pediatric critical care medicine fellow in the department of pediatric critical care medicine at the University of California, San Francisco in San Francisco, California, USA. Published: 10/15/2020

SCCM Pod-424 Critical Care Implications of Respiratory Depression on Hospital Wards
Continuous monitoring on hospital wards can prevent adverse events and unnecessary ICU admissions. Michael Smith, MD, is joined by Ashish K. Khanna, MD, FCCP, FCCM, to review the demographics of respiratory depression, including opioid-induced respiratory depression on surgical and medical wards, and to correlate the results of the PRODIGY trial with the clinical practice of critical care medicine. Dr. Khanna is staff intensivist and anesthesiologist, associate professor of anesthesiology, and section head for research with the Department of Anesthesiology, Section on Critical Care Medicine at Wake Forest University School of Medicine in Winston-Salem, North Carolina, USA. This podcast is supported by an unrestricted education grant by Medtronic. Published: 10/7/2020

SCCM Pod-423 Coagulopathy in COVID-19 Patients

COVID-19 is associated with a high prevalence of coagulopathy and venous thromboembolism. Host Kyle B. Enfield, MD, FCCM, talks with Jerrold H. Levy, MD, FAHA, FCCM, about what clinicians need to know about this serious problem and how it impacts care delivery (Iba et al. Crit Care Med. 2020;48:1358-1364). Dr. Levy is professor of anesthesiology, critical care professor of surgery (cardiothoracic), and codirector of the cardiothoracic ICU at Duke University Hospital in Durham, North Carolina, USA. This podcast is sponsored by BioFire.

Published: 9/30/2020

SCCM Pod-422 Procalcitonin in COVID-19 and Influenza-Related Secondary Bacterial Infections
Procalcitonin testing on admission seems to be a valuable piece of information for early risk assessment and ruling out bacterial co-infection in COVID-19 patients. Host Pamela M. Peeke, MD, MPH, is joined by Michael Broyles, PharmD, and Eric H. Gluck, MD, to explore this topic. Dr. Broyles is director of pharmacy and laboratory services at Five Rivers Medical Center in Pocahontas, Arkansas, USA, and Dr. Gluck is director of critical care services at Swedish Covenant Chicago in Chicago, Illinois, USA. This podcast is sponsored by Thermo Fisher Scientific. Published: 9/24/2020

SCCM Pod-421 COVID-19 and Renal Replacement Therapy
The increase in acute kidney injury in COVID-19 patients is resulting in more utilization of renal replacement therapy (RRT) and continuous renal replacement therapy (CRRT). Host Pamela M. Peeke, MD, MPH, FACP, FACSM , is joined by Michael J. Connor Jr, MD, to review RRT utilization and best practices in COVID-19, what hospitals are doing to prepare for a surge in RRT, and how to mitigate anticoaguability in CRRT. Dr. Connor is associate professor of medicine in critical care medicine and nephrology at Emory University in Atlanta, Georgia, USA. This podcast is sponsored by Baxter Healthcare. Published: 9/18/2020

SCCM Pod-420 Nebulized Bacteriophages for Prophylaxis of Experimental MRSA VAP
Alternative strategies are needed to combat and prevent antibiotic-resistant bacterial infections. Host Ashish K. Khanna, MD, FCCP, FCCM, talks with David R. Cameron, PhD, about the potential for bacteriophage prophylaxis in the context of experimental ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus in rats (Prazak J, et al. Crit Care Med. 2020;48:1042-1046). Dr. Cameron is research group leader in the department of intensive care medicine at Inselspital, Bern University Hospital in Bern, Switzerland. Published: 9/10/2020