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Content Type: Articles

Subcutaneous Enoxaparin Safely Facilitates Bedside Sustained Low-Efficiency Hemodialysis in Hypercoagulopathic Coronavirus Disease 2019 Patients - A Proof-of-Principle Trial

This study describes a simple and safe protocol of anticoagulation with low molecular weight heparin (LMWH) in combination with bedside sustained low efficiency hemodialysis (SLED) in COVID-19 patients.

   Estimated Time: 09:16 min Anticoagulation, Coronavirus, COVID-19

Less Can Be More When Targeting Interleukin-6-Mediated Cytokine Release Syndrome in Coronavirus Disease 2019

Cytokine release syndrome (CRS) mediated by IL-6 is a critical driver of COVID-19 mortality. The authors review and discuss key immunologic effects of direct IL-6 blockade, downstream non-selective JAK inhibition, and selective JAK2 suppression to treat COVID-19-related CRS.

   Estimated Time: 12:04 min Comorbidities, Coronavirus, COVID-19, Diagnosis and Testing

Coagulopathy of Coronavirus Disease 2019

From Critical Care Medicine. Recent studies have reported a high incidence of thrombotic events in COVID-19. However, the significance of thromboembolic complications has not been widely appreciated. The purpose of this review is to provide current knowledge of this serious pr...

   Estimated Time: 24:24 min Anticoagulation, Coronavirus, COVID-19, Therapies

Children in Critical Care Due to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Experience in a Spanish Hospital

From Pediatric Critical Care Medicine. This study aims to describe a series of children admitted to a pediatric intensive care unit in Spain, one of the countries severely affected by the coronavirus. disease 2019 (COVID-19).

   Estimated Time: 14:16 min ARDS, Coronavirus, COVID-19

Just-in-Time Simulation to Guide Workflow Design for Coronavirus Disease 2019 Difficult Airway Management

From Pediatric Critical Care Medicine. Integration of table-top planning, in situ simulations, and debriefing of real COVID19 cases can enhance planning, training, job aids, and feasible policies/procedures that address human factors, team communication, equipment choice, and ...

   Estimated Time: 18:14 min Coronavirus, COVID-19, Supportive Care, Ventilatory Support

Editorial: Finding the Right Ethical Framework for PICU Resource Allocation During a Pandemic

From Pediatric Critical Care Medicine. An editorial in response to an article by Killien et al. on resource "Prediction of Pediatric Critical Care Resource Utilization for Disaster Triage," noting that, although uniform use of the version of PELOD-2 proposed by Killien et al. ...

   Estimated Time: 07:29 min Coronavirus, COVID-19, Pediatrics, Triage

Routine Venous Thromboembolism Prophylaxis May Be Inadequate in the Hypercoagulable State of Severe Coronavirus Disease 2019

From Critical Care Medicine. The authors sought to determine the frequency of venous thromboembolism in critically ill coronavirus disease 2019 patients and associate a degree of inflammatory marker elevation to venous thromboembolism development. They found that routine chemi...

   Estimated Time: 24:31 min Coronavirus, COVID-19, Therapies

Implications of Obesity for the Management of Severe Coronavirus Disease 2019 Pneumonia

From Critical Care Medicine. The authors report on their experience from their first 44 cases of 95 COVID-19 critically ill patients and analyze the link between obesity and this new form of 96 ARDS caused by the SARS-CoV-2 with its potential implications for patients' managem...

   Estimated Time: 23:23 min Coinfections, Coronavirus, COVID-19, Ventilatory Support

ICU and Ventilator Mortality Among Critically Ill Adults With Coronavirus Disease 2019

From Critical Care Medicine. To help address the growing concern that critical illness, and specifically mechanical ventilation, are associated with a high risk of death, the authors conducted a retrospective cohort study of critically ill patients with COVID-19 across their a...

   Estimated Time: 15:48 min Coronavirus, COVID-19, Supportive Care, Ventilatory Support

Letter to the Editor: The Role of the Pediatric Intensivist in the Coronavirus Disease 2019 Pandemic

From Pediatric Intensive Care Medicine. In this letter to the editor, the authors explore the role of pediatric intensivists, as highly-skilled professionals, in the care of critically ill adults. With adequate guidance by professional societies and adult intensivists, pediatr...

   Estimated Time: 05:38 min Coronavirus, COVID-19, Pediatrics

Percutaneous Tracheostomy With Apnea During Coronavirus Disease 2019 Era: A Protocol and Brief Report of Cases

From Critical Care Explorations. The authors sought to modify their current procedure for performing percutaneous tracheostomy to minimize aerosolization in hopes that it would help reduce exposure to staff involved. They concluded that percutaneous tracheostomy performed with...

   Estimated Time: 15:27 min Coronavirus, COVID-19, Supportive Care

Letter to the Editor: The Importance of Universal Preprocedural Testing for the Novel Coronavirus 2019

From Critical Care Explorations. In this letter to the editor, the authors recommend universal preprocedural testing and other interventions to safeguard healthcare personnel and patients.

   Estimated Time: 08:13 min Coronavirus, COVID-19, Diagnosis and Testing, Infection Control

Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019-Induced Acute Respiratory Distress Syndrome: A Multicenter Descriptive Study

From Critical Care Medicine. This study aims to summarize the clinical features, ECMO characteristics, and outcomes of patients with SARS-CoV-2 pneumonia receiving ECMO. The authors conclude ECMO might be an effective salvage treatment for patients with SARS27 CoV-2 pneumonia ...

   Estimated Time: 18:28 min Coronavirus, COVID-19, ECMO

Editorial - Coronavirus Disease 2019 Triage Teams: Death by Numbers

From Critical Care Medicine. An editorial associated with Sprung et al. article ("Adult Intensive care unit triage during the COVID-19 pandemic - Who will live and who will die? Recommendations to improve survival"), stating that the concept of the triage committee has disturb...

   Estimated Time: 08:30 min Coronavirus, COVID-19, Triage

Letter to the Editor: The Role of Lung Ultrasound in Diagnosis and Follow-Up of Children With Coronavirus Disease 2019

From Pediatric Critical Care Medicine. In this letter to the editor, the authors respond to an article by Ong et al. and recommend lung ultrasound in children with COVID-19 as a means of improving outcomes.

   Estimated Time: 02:39 min Coronavirus, COVID-19, Pediatrics, Ultrasound

Extracorporeal Membrane Oxygenation for Pediatric Patients With Coronavirus Disease 2019–Related Illness

From Pediatric Critical Care Medicine. The authors describe current hospital guidelines and the opinions of extracorporeal membrane oxygenation leaders at U.S. children’s hospitals concerning the use of extracorporeal membrane oxygenation for coronavirus disease 2019–positive ...

   Estimated Time: 11:44 min Coronavirus, COVID-19, ECMO

Frequency of Continuous Renal Replacement Therapy Use Early in Coronavirus Disease 2019 Pandemic

From Critical Care Explorations. The authors reviewed the available literature to understand the frequency of continuous renal replacement therapy use among patients with coronavirus disease 2019 who required intensive care.

   Estimated Time: 08:32 min AKI/Renal, Coronavirus, COVID-19

Critical Care Clinician Reports on Coronavirus Disease 2019: Results From a National Survey of 4,875 ICU Providers

This study queried United States (U.S.) ICU clinician perspectives on ICU preparedness and concerns regarding delivering COVID-19 patient care.

   Estimated Time: 20:21 min Coronavirus, COVID-19

Letter to the Editor: Evidence of Steroids in Patients With Acute Respiratory Distress Syndrome in Coronavirus Disease 2019

From Critical Care Explorations. A letter to the editor in response to Villar et al. article on corticosteroids and COVID-19.

   Estimated Time: 05:21 min ARDS, Coronavirus, COVID-19, Therapies

Proposal for Coronavirus Disease 2019 Management

From Critical Care Explorations. During a pandemic, with limited resources, we should provide the safest and most effective care, while protecting caregivers.The authors propose ways to do that.

   Estimated Time: 13:35 min Clinical presentations, Coronavirus, COVID-19, Infection Control