Rapid Transition of a PICU Space and Staff to Adult Coronavirus Disease 2019 ICU Care

From Critical Care Medicine The authors describe how a PICU and a PICU care team were incorporated into a hospital-wide ICU care model during the coronavirus disease 2019 pandemic.

Letter to the Editor: Predictors of Mortality and Effect of Drug Therapies in Mechanically Ventilated Patients With Coronavirus Disease 2019: A Multicenter Cohort St

From Critical Care Explorations The authors conducted a multicenter cohort study to determine the effect of drug therapies on survival in mechanically ventilated patients with coronavirus disease 2019.

Delirium Incidence, Duration, and Severity in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations The authors found that mechanical ventilation was significantly associated with odds of delirium even after adjustment for sedatives.

Brain Death Evaluation in Children With Suspected or Confirmed Coronavirus Disease 2019

From Pediatric Critical Care Medicine The authors discuss the challenges of conducting a death by neurologic criteria or brain death evaluation in the coronavirus disease 2019 era and provide guidance to mitigate viral transmission risk and maintain patient safety during ...

Feasibility and Safety of Prone Position Transport for Severe Hypoxemic Respiratory Failure Due to Coronavirus Disease 2019

From Critical Care Explorations The authors found that critical care transport of severe hypoxemic respiratory failure patients with coronavirus disease 2019 in the prone position is safe when performed by a dedicated team of critical care nurse and paramedics with an est...

Experience With Cardiology-Oriented Outcomes in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations The authors share data and recommendations from a multidisciplinary team to highlight our institution’s clinical experiences and guidelines for managing cardiovascular complications of coronavirus disease 2019.

A Novel Low-Cost Ventilator for Use in a Worldwide Pandemic: The Portsmouth Ventilator

From Critical Care Explorations In this study, the authors found that the Portsmouth Ventilator was able to perform well across all simulated pathologies and in vivo.

Clinical Pharmacists: An Invaluable Part of the Coronavirus Disease 2019 Frontline Response

From Critical Care Explorations The authors describe how clinical pharmacists fulfilled an essential service during the coronavirus pandemic by working to ensure the best possible outcomes for the patients they served on the frontline.

A Method to Improve Continuous Renal Replacement Therapy Circuit Survival Time in Critically Ill Coronavirus Disease 2019 Patients With Acute Kidney Injury

From Critical Care Explorations The authors discuss optimizing continuous renal replacement therapy circuit survival in coronavirus disease 2019 patients admitted to the ICU.

Letter to the Editor: Caution Is Needed When Reporting or Pooling the Prevalence of Venous Thromboembolism in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Medicine In this Letter to the Editor, the author discusses the difficulties to ascertain in ICU settings the exact VTE incidence, incidence rate, or prevalence due to various reasons, including the absence of uniform screening at ICU admission to exclu...

The Use of High-Flow Nasal Oxygen in the ICU as a First-Line Therapy for Acute Hypoxemic Respiratory Failure Secondary to Coronavirus Disease 2019

From Critical Care Explorations The authors characterize outcomes associated with high-flow nasal oxygen use in critically ill adult patients with coronavirus disease 2019-associated acute hypoxemic respiratory failure.

The Ties That Bind: A Coronavirus Disease Journey

From Critical Care Explorations In this article, the authors describe a personal experience of COVID-19 bringing two old friends together and the patient care lessons learned.

Evaluation of the Efficacy and Safety of Inhaled Epoprostenol and Inhaled Nitric Oxide for Refractory Hypoxemia in Patients With Coronavirus Disease 2019

From Critical Care Explorations In this study, the authors evaluated the efficacy and safety of inhaled epoprostenol and inhaled nitric oxide in patients with refractory hypoxemia secondary to coronavirus disease 2019.

Spectrum of Vascular Involvement in Coronavirus Disease 2019 Pneumonia—Findings on CT Perfusion

From Critical Care Explorations In this article, the authors observed and interpreted CT perfusion patterns of COVID-19 pulmonary features.

Timing of Intubation and In-Hospital Mortality in Patients With Coronavirus Disease 2019

From Critical Care Explorations The authors examined whether increasing time between admission and intubation was associated with mortality in patients with coronavirus disease 2019 who underwent mechanical ventilation.

Metabolomics Profiling of Critically Ill Coronavirus Disease 2019 Patients: Identification of Diagnostic and Prognostic Biomarkers

From Critical Care Explorations The authors performed metabolomics profiling of critically ill coronavirus disease 2019 patients to understand better the underlying pathologic processes and pathways, and to identify potential diagnostic/prognostic biomarkers.

Resolution of Coronavirus Disease 2019 Infection and Pulmonary Pathology With Nebulized DAS181: A Pilot Study

From Critical Care Explorations The authors investigated the safety and effects of nebulized DAS181 on hypoxic coronavirus disease 2019 patients.

Benchmarking Critical Care Well-Being: Before and After the Coronavirus Disease 2019 Pandemic

From Critical Care Explorations The authors examined the impact of COVID-19 with regard to well-being, measured as burnout and professional fulfillment, across critical care healthcare professionals, ICUs, and hospitals within a health system.

Volatile Isoflurane in Critically Ill Coronavirus Disease 2019 Patients—A Case Series and Systematic Review

From Critical Care Explorations The authors evalute the use of isoflurane in patients with coronavirus disease 2019–induced acute respiratory distress syndrome.

Almitrine Infusion in Severe Acute Respiratory Syndrome Coronavirus 2-Induced Acute Respiratory Distress Syndrome: A Single-Center Observational Study

From Critical Care Medicine The authors assessed the effect of almitrine, a selective pulmonary vasoconstrictor, on arterial oxygenation in severe acute respiratory syndrome coronavirus 2-induced acute respiratory distress syndrome.