Clinical Outcomes Following Tocilizumab Administration in Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this study, the authors examined the outcomes of critically ill coronavirus disease 2019 patients treated with tocilizumab and factors associated with clinical improvement.

Antiviral Dosing Modification for Coronavirus Disease 2019–Infected Patients Receiving Extracorporeal Therapy

From Critical Care Explorations. In this study, the authors gathered available published resources including physicochemical and pharmacokinetic properties and suggest antiviral drug dosing adaptation for coronavirus disease 2019–infected critically ill patients receiving extr...

Dexmedetomidine-Associated Hyperpyrexia in Three Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Explorations . In this study of three patients, the authors state that their findings suggest that high doses of dexmedetomidine infusion are associated with hyperpyrexia in a seemingly dose-dependent fashion in critically ill patients with coronavirus dise...

Relocating IV Pumps for Critically Ill Isolated Coronavirus Disease 2019 Patients From Bedside to Outside the Patient Room

From Critical Care Explorations. The authors discuss advantages and disadvantages of relocating IV pumps for coronavirus disease 2019 patients from bedside to outside the patient room and characterize reproducible details of an external infusion pump model.

Letter to Editor: In Response to "Coagulopathy of Coronavirus Disease 2019"

From Critical Care Medicine. This Letter to the Editor is in response to the article "Coagulopathy of Coronavirus 2019" by Iba et a.

Role for Anti-Cytokine Therapies in Severe Coronavirus Disease 2019

From Critical Care Explorations. In this narrative review, the authors summarize existing knowledge of the immune response to coronavirus infection and highlight the current and potential future roles of therapeutic strategies to combat the hyperinflammatory response of patien...

Renin-Angiotensin System and COVID-19

This presentation is a review of the renin-angiostensin System and COVID-19. This is SCCM curated COVID-19 microlearning content.

COVID-19 Pharmacology Debates: Management of Delirium, Pain and Sedation

The Society of Critical Care Medicine (SCCM) and the American Society of Health-System Pharmacists (ASHP) in their third series of therapeutic debates in the management of COVID-19.

COVID-19 Pharmacology Debates: Steroid and Antiviral Use in COVID-19 Patients

ASHP and the SCCM teamed up in their second series of therapeutic debates in the management of COVID-19. In the first debate, the content matter experts reviewed the latest literature and debate the use of steroids for treatment of COVID-19.

A Centrally Acting Antihypertensive, Clonidine, Sedates Patients Presenting With Acute Respiratory Distress Syndrome Evoked by Severe Acute Respiratory Syndrome-Coronavirus 2

From Critical Care Medicine. The authors report on a sedation and ventilation method used in France.

Incidence of Venous Thromboembolism in Critically Ill Coronavirus Disease 2019 Patients Receiving Prophylactic Anticoagulation

From Critical Care Medicine. Deep venous thrombosis is very common in critically ill patients with coronavirus disease 2019, so the authors describe the prevalence of venous thromboembolism in critically ill patients receiving different regimens of prophylactic anticoagulation.

Letter to the Editor: Optimizing the Risk-Benefit Balance of Thromboprophylaxis in Critically Ill Patients With Coronavirus Disease 2019

From Critical Care Medicine. This Letter to the Editor is in response to an article by Iba et al. (Coagulopathy of Coronavirus Disease 2019) and discusses dosing recommendations of low molecular weight heparin.

Procedures for COVID-19 Cohort Units: Building an Operating Room in a COVID-19 Cohort ICU

This presentation provides procedures for building COVID-19 cohort units. This is SCCM curated COVID-19 microlearning content.

Letter to the Editor: Thromboprophylaxis in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Explorations. In this Letter to the Editor, the authors report their adapted thromboprophylaxis practice of low-molecular-weight heparin administration in coronavirus disease 2019 ICU patients.

Alternative Analgesic and Sedative Agents in the Setting of Drug Shortages during the COVID19 Pandemic

This resources detail how to manage drug shortages for alternative analgesics and sedagent agents. This is SCCM curated COVID-19 microlearning content.

What data support the use of convalescent plasma? Do you have experience with it? Which patients should be treated with it?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.

Can you give an update on the current literature on using steroids in the treatment of COVID-19? How are you using this literature in your practice?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.

Which patients should be treated with remdesivir and when should it be initiated?

Questions from social media, blogs and the various discussion forums, including the new SCCM COVID-19 Discussion Group, were answered. This microlearning content was taken from the COVID-19 Critical Care for Non-ICU Clinicians: Expert Panel Series held on July 8th, 2020.

Consideration of Severe Coronavirus Disease 2019 As Viral Sepsis and Potential Use of Immune Checkpoint Inhibitors

From Critical Care Explorations. Supportive treatment and immunomodulators have a critical place in the treatment of severe patients until effective antivirals are developed. Interleukin-6 antagonists, one of the immunomodulating agents, appears to be effective in the treatmen...

The Combination of Tocilizumab and Methylprednisolone Along With Initial Lung Recruitment Strategy in Coronavirus Disease 2019 Patients Requiring Mechanical Ventilation: A Series of 21 Consecutive Cases

From Critical Care Explorations. This articles describes the outcomes with use of a combination of tocilizumab and 34 methylprednisolone administered around the time of endotracheal intubation in patients with 35 confirmed COVID-19-associated hypoxemic respiratory failure requ...