Awake Proning with High Flow Nasal Cannula in COVID-19 ARDS

This resource details an the usage of awake proning with high flow nasal cannula in COVID ARDS. This is SCCM curated COVID-19 microlearning content.

Epidemiological and Clinical Characterization of Superinfections in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Explorations . Prevalence of superinfections in coronavirus disease 2019 patients requiring mechanical ventilation was high in this series, and bacterial superinfections were independently associated with ICU or 28-day mortality (whichever comes first).

Examination of Early CNS Symptoms and Severe Coronavirus Disease 2019: A Multicenter Observational Case Series

From C ritical Care Explorations . In this observational study, the authors found that early CNS symptoms, and pecifically encephalopathy, are differentially associated with risk of severe coronavirus disease 2019 and may serve as an early marker for differences in clinical di...

Scarce Resource Allocation in a Pandemic: A Protocol to Promote Equity, Timeliness, and Transparency

From Critical Care Explorations . Drawing on expertise in critical care medicine, bioethics, and political science, the authors propose a decision-making protocol to ensure fairness in the resolution of conflict, timely decision-making, and accountability to improve system re...

Using Nonheparin Anticoagulant to Treat a Near-Fatal Case With Multiple Venous Thrombotic Lesions During ChAdOx1 nCoV-19 Vaccination-Related Vaccine-Induced Immune Thrombotic Thrombocytopenia

From Critical Care Medicine . The authors describe the successful recovery from multiple and life-threatening venous thrombosis after ChAdOx1 nCoV-19 vaccination.

Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2–Related Multisystem Inflammatory Syndrome in Children With Shock

From Critical Care Medicine . In this article, the authors found that endothelial dysfunction is associated with severe acute respiratory syndrome coronavirus 2–related multisystem inflammatory syndrome in children with shock and may constitute one of the underlying mechanisms.

Return to Work After Coronavirus Disease 2019 Acute Respiratory Distress Syndrome and Intensive Care Admission: Prospective, Case Series at 6 Months From Hospital Discharge

From Critical Care Medicine . In this Online Brief Report, the authors describe rates of return to work versus unemployment following coronavirus disease 2019 acute respiratory distress syndrome requiring intensive care admission.

Awake Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019 Patients Without Invasive Mechanical Ventilation

From Critical Care Explorations . This is a case report on the use of awake extracorporeal membrane oxygenation as a “treatment” for barotrauma due to severe acute respiratory distress syndrome in a coronavirus disease 2019 patient, without the need for invasive mechanical ve...

Development and Validation of ARC, a Model for Anticipating Acute Respiratory Failure in Coronavirus Disease 2019 Patients

From Critical Care Explorations . In this predictive modeling report, the authors sought to evaluate factors predictive of clinical progression among coronavirus disease 2019 patients following admission, and whether continuous, automated assessments of patient status may con...

Online Letter to the Editor: Optimal Management of Thrombotic Complications in Patients With Coronavirus Disease 2019

From Critical Care Medicine . This Online Letter to the Editor was written in response to an article by Mirsadraee et al. entitled “Prevalence of Thrombotic Complications in ICUTreated Patients With Coronavirus Disease 2019 Detected With Systematic CT Scanning.”

Online Letter to the Editor: Reasons for the Overuse of Sedatives and Deep Sedation for Mechanically Ventilated Coronavirus Disease 2019 Patients

From Critical Care Medicine . This Online Letter to the Editor was written in response to an article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019-Related Acute Respir...

Online Letter to the Editor: The Janus Face of Coronavirus Disease 2019–Associated Coagulopathy

From Critical Care Medicine . This Online Letter to the Editor is in response to an article by Doyle et al. entitled “A comparison of thrombosis and hemorrhage rates in patients with severe respiratory failure due to coronavirus disease 2019 and influenza requiring extracorpo...

Online Letter to Editor: Optimal Patient Selection for the Prophylactic Anticoagulation Therapy in Patients With Coronavirus Disease 2019

From Critical Care Medicine . This Online Letter to the Editor was written in response to an article by Santoro et al. entitled “Anticoagulation Therapy in Patients With Coronavirus Disease 2019: Results From a Multicenter International Prospective Registry (Health Outcome Pr...

Editorial: Glucocorticoid-Glucocorticoid Receptor Response to Severe Acute Respiratory Syndrome Coronavirus 2

From Critical Care Medicine . This Editorial accompanies an article by Vassiliou et al. entitled “Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients.”

Editorial: The Long Road to Normalcy Following Survival From COVID-19–Associated Acute Respiratory Distress Syndrome

From Critical Care Medicine . This editorial accompanies an article by Carenzo et al. entitled “Return to Work After Coronavirus Disease 2019 Acute Respiratory Distress Syndrome and Intensive Care Admission: Propsective, Case-Series at 6 Months From Hospital Discharge” and ca...

Editorial: Coronavirus Disease 2019: There Is a Heart Between the Lungs

From Critical Care Medicine . This Editorial was written in response to the article by Chotalia et al. “Right Ventricular Dysfunction and Its Association With Mortality in Coronavirus Disease 2019 Acute Respiratory Distress Syndrome.”

Editorial: Utility of Coronavirus Disease 2019 Immune Profiling for the Clinician at the Bedside

From Critical Care Medicine . This Editorial was written in response to the article by de Roquetaillade et al. entitled “Comparison of Circulating Immune Cells Profiles and Kinetic Between Coronavirus Disease 2019 and Bacterial Sepsis,” which explores the relationship between...

Coronavirus Disease 2019: A Pandemic Spawning an Infodemic

From Pediatric Critical Care Medicine . In this Special Article, the authors make a call for the field of pediatric critical care to “move forward.” They note that, over a short period, some of the best science and resources have been applied to children with COVID-19 or MIS-...

Increased Glucocorticoid Receptor Alpha Expression and Signaling in Critically Ill Coronavirus Disease 2019 Patients

From Critical Care Medicine . In this study, the authors found that ICU coronavirus disease 2019 patients showed upregulated glucocorticoid receptor alpha and glucocorticoid-inducible leucine zipper expression, along with cortisol levels, compared with ICU noncoronavirus dise...

Editorial: Do Our Sedation Practices Contribute to Increased Mortality in Coronavirus Disease 2019–Related Acute Respiratory Distress Syndrome?

From Critical Care Medicine . In this Editorial, the authors discuss the article by Wongtangman et al. entitled “Association of Sedation, Coma, and In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019–Related Acute Respiratory Distress Syndr...