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The National Institute of General Medical Sciences (NIGMS) is changing its priorities to invest in sepsis research in a more targeted and strategic way.
In an important opportunity to help shape the future of sepsis research, NIGMS has issued a request for information related to its new priorities.
This request is a response to a report submitted by the National Advisory General Medical Sciences Council (NAGMSC) Working Group on Sepsis. Former SCCM President Craig M. Coopersmith, MD, FACS, FCCM, participated as a member of the working group.
“Sepsis is a devastating public health problem. Despite significant advances made over the past 20 years in our understanding of the pathophysiology of sepsis, we have been unsuccessful in translating these insights into new therapies we can use at the bedside of our patients. Novel approaches are therefore urgently needed in our battle against the most common killer in our ICUs,” said Dr. Coopersmith.
Among the topics NIGMS is seeking comment on are:
Underlining the importance of this data collection, Dr. Coopersmith noted that "there is a tremendous opportunity for us to leverage samples taken from septic and control patients in biorepositories that can be used to understand mechanisms of sepsis and potentially help identify novel therapeutics and/or test the efficacy of candidate agents."
"Understanding the most effective methods of biobanking specimens from septic patients – as well as the challenges we face in meeting this goal – has potential far-reaching implications for our ultimate goal of developing effective therapeutics for sepsis," said Dr. Coopersmith.