Publications

Discovery, the Critical Care Research Network Publications

Current practices and safety of medication use during rapid sequence intubation
Groth C, Acquisto NM, Khadem T.  Current practices and safety of medication use during rapid sequence intubation:  A multicenter study evaluating practices across the United States.  J Crit Care  2018;45:65-70. Epub 2018 Jan 30.

Early risk factors and the role of fluid administration in developing acute respiratory distress syndrome in septic patients
Seethala RR, Hou PC, Aisiku IP, Frendl G, Park PK, Mikkelsen ME, Chang SY, Gajic O, Sevransky J. Early risk factors and the role of fluid administration in developing acute respiratory distress syndrome in septic patients. Ann Intensive Care. 2017 Dec;7(1):11.

Randomized Clinical Trial of a Combination of an Inhaled Corticosteroid and Beta Agonist in Patients at Risk of Developing the Acute Respiratory Distress Syndrome
Festic E, Carr GE, Cartin-Ceba R, Hinds RF, Banner-Goodspeed V, Bansal V, Asuni AT, Talmor D, Rajagopalan G, Frank RD, Gajic O, Matthay MA, Levitt JE. Randomized Clinical Trial of a Combination of an Inhaled Corticosteroid and Beta Agonist in Patients at Risk of Developing the Acute Respiratory Distress Syndrome. Crit Care Med. 2017 May;45(5):798-805.

(USCIIT-SI-ALI) Risk Factors for In-Hospital Mortality in Smoke Inhalation-Associated Acute Lung Injury: Data From 68 United States Hospitals
Kadri SS, Miller AC, Hohmann S, Bonne S, Nielsen C, Wells C, Gruver C, Quraishi SA, Sun J, Cai R, Morris PE, Freeman BD, Holmes JH, Cairns BA, Suffredini AF. US Critical Illness and Injury Trials Group: Smoke Inhalation-associated Acute Lung Injury (SI-ALI) Investigators (USCIIT-SI-ALI) Risk Factors for In-Hospital Mortality in Smoke Inhalation-Associated Acute Lung Injury: Data From 68 United States Hospitals. Chest. 2016 Dec;150(6):1260-1268.

Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN): Evolution of a content management system for point-of-care clinical decision support
Barwise A, Garcia-Arguello L, Dong Y, Hulyalkar M, Vukoja M, Schultz MJ, Adhikari NK, Bonneton B, Kilickaya O, Kashyap R, Gajic O, Schmickl CN.  Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN): Evolution of a content management system for point-of-care clinical decision support. BMC Med Inform Decis Mak. 2016 Oct 3;16(1):127.

(USCIITG: LIPS-A) Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial
Kor DJ, Carter RE, Park PK, Festic E, Banner-Goodspeed VM, Hinds R, Talmor D, Gajic O, Ware LB, Gong MN. US Critical Illness and Injury Trials Group: Lung Injury Prevention with Aspirin Study Group (USCIITG: LIPS-A) Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial. JAMA. 2016 Jun 14;315(22):2406-14.

(USCIITG: LIPS-A) Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial
Kor DJ, Carter RE, Park PK, Festic E, Banner-Goodspeed VM, Hinds R, Talmor D, Gajic O, Ware LB, Gong MN; US Critical Illness and Injury Trials Group: Lung Injury Prevention with Aspirin Study Group (USCIITG: LIPS-A). Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial. JAMA. 2016 Jun 14;315(22):2406-14. 

A Multicenter Evaluation of Prolonged Empiric Antibiotic Therapy in Adult ICUs in the United States
Thomas Z, Bandali F, Sankaranarayanan J, Reardon T, Olsen K. A Multicenter Evaluation of Prolonged Empiric Antibiotic Therapy in Adult ICUs in the United States. Crit Care Med. 2015 Dec;43(12):2527-34.

(USCIITG–LIPS) SpO2/FiO2 ratio on hospital admission is an indicator of early acute respiratory distress syndrome development among patients at risk
Festic E, Bansal V, Kor DJ, Gajic O. US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS) SpO2/FiO2 ratio on hospital admission is an indicator of early acute respiratory distress syndrome development among patients at risk. J Intensive Care Med. 2015 May;30(4):209-16.

Checklist for early recognition and treatment of acute illness: International collaboration to improve critical care practice
Vukoja M, Kashyap R, Gavrilovic S, Dong Y, Kilickaya O, Gajic O. Checklist for early recognition and treatment of acute illness: International collaboration to improve critical care practice. World J Crit Care Med. 2015 Feb 4;4(1):55-61.

Critical Care Pharmacotherapy Trials Network. A multicenter study of the point prevelance of drug-induced hypotension in the ICU
Kane-Gill SL, LeBlanc JM, Dasta JF, Devabhakthuni S. Critical Care Pharmacotherapy Trials Network. A multicenter study of the point prevelance of drug-induced hypotension in the ICU. Crit Crit Care Med. 2014 Oct; 42(10):2197-2203.

CERTAIN Investigators. A survey on critical care resources and practices in low- and middle-income countries
Vukoja M, Riviello E, Gavrilovic S, Adhikari NK, Kashyap R, Bhagwanjee S, Gajic O, Kilickaya O. CERTAIN Investigators. A survey on critical care resources and practices in low- and middle-income countries. Glob Heart. 2014 Sep;9(3):337-42.e1-5 

(USCIITG–LIPS) Obstructive sleep apnea, obesity, and the development of acute respiratory distress syndrome
Karnatovskaia LV, Lee AS, Bender SP, Talmor D, Festic E. US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS) Obstructive sleep apnea, obesity, and the development of acute respiratory distress syndrome. J Clin Sleep Med. 2014 Jun 15;10(6):657-62.

(USCIITG-LIPS) Prehospital use of inhaled corticosteroids and point prevalence of pneumonia at the time of hospital admission: secondary analysis of a multicenter cohort study
Festic E, Bansal V, Gajic O, Lee AS. United States Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS) Prehospital use of inhaled corticosteroids and point prevalence of pneumonia at the time of hospital admission: secondary analysis of a multicenter cohort study. Mayo Clin Proc. 2014 Feb;89(2):154-62.

(USCIITG-LIPS) Prehospital use of inhaled steroids and incidence of acute lung injury among patients at risk
Festic E, Ortiz-Diaz E, Lee A, Li G, Kor DJ, Adebola A, Akca O, Hoth J, Levitt JE, Carter R, Gajic O. United States Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS). Prehospital use of inhaled steroids and incidence of acute lung injury among patients at risk. J Crit Care. 2013 Dec;28(6):985-91. 

(USCIITG–LIPS) The influence of prehospital systemic corticosteroid use on development of acute respiratory distress syndrome and hospital outcomes
Karnatovskaia LV, Lee AS, Gajic O, Festic E. U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS) The influence of prehospital systemic corticosteroid use on development of acute respiratory distress syndrome and hospital outcomes. Crit Care Med. 2013 Jul;41(7):1679-85.

(USCIITG-LIPS) Sex, race, and the development of acute lung injury
Lemos-Filho LB, Mikkelsen ME, Martin GS, Dabbagh O, Adesanya A, Gentile N, Esper A, Gajic O, Gong MN. US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS) Sex, race, and the development of acute lung injury. Chest. 2013 Apr;143(4):901-909.

(USCIITG-LIPS) Contemporary ventilator management in patients with and at risk of ALI/ARDS
Chang SY, Dabbagh O, Gajic O, Patrawalla A, Elie MC, Talmor DS, Malhotra A, Adesanya A, Anderson HL 3rd, Blum JM, Park PK, Gong MN. United States Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS) Contemporary ventilator management in patients with and at risk of ALI/ARDS. Respir Care. 2013 Apr;58(4):578-88.

United States Critical Illness and Injury Trials Group
Blum JM, Morris PE, Martin GS, Gong MN, Bhagwanjee S, Cairns CB, Cobb JP. United States Critical Illness and Injury Trials Group. Chest. 2013 Mar;143(3):808-813.

(USCIITG-LIPS) Preshospital amiodarone may increase the incidence of acute respiratory distress syndrome among patients at risk
Karnatovskaia LV, Festic E, Gajic O, Carter RE, Lee AS. US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS). Preshospital amiodarone may increase the incidence of acute respiratory distress syndrome among patients at risk. J Crit Care. 2012 Oct;27(5):447-53.

Perceived versus actual sedation practices in adult intensive care unit patients receiving mechanical ventilation
Gill KV, Voils SA, Chenault GA, Brophy GM. Perceived versus actual sedation practices in adult intensive care unit patients receiving mechanical ventilation. Ann Pharmacother. 2012 Oct; 46 (10): 1331-9.

(USCIITG: LIPS-A) Lung Injury Prevention with Aspirin (LIPS-A): A protocol for a multicenter randomised clinical trial in medical patients at high risk of acute lung injury
Kor DJ, Talmor DS, Banner-Goodspeed VM, Carter RE, Hinds R, Park PK, Gajic O, Gong MN. US Critical Illness and Injury Trials Group: Lung Injury Prevention with Aspirin Study Group (USCIITG: LIPS-A). Lung Injury Prevention with Aspirin (LIPS-A): A protocol for a multicenter randomised clinical trial in medical patients at high risk of acute lung injury. BMJ Open. 2012 Sep 4;2(5).

(USCIITG–LIPS 1) Lung injury prediction score for the emergency department: first steps towards prevention in patients at risk
Elie-Turenne MC, Hou PC, Mitani A, Barry JM, Kao EY, Cohen JE, Frendl G, Gajic O, Gentile NT. US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS 1.) Lung injury prediction score for the emergency department: first steps towards prevention in patients at risk. Int J Emerg Med. 2012 Sep 3;5(1):33

Critical Care Societies Collaborative, USCIITG Task Force on Critical Care Research. Multisociety Task Force for Critical Care Research: Key issues and recommendations
Deutschman CS, Ahrens T, Cairns CB, Sessler CN, Parsons PE. Critical Care Societies Collaborative, USCIITG Task Force on Critical Care Research. Multisociety Task Force for Critical Care Research: Key issues and recommendations. Crit Care Med. 2012 Jan;40

Critical Illness Outcomes Study: An Observational Study on Protocols and Mortality in Intensive Care Units
Ali NA, Gutteridge D, Shahul S, Checkley W, Sevransky J, Martin GS. Critical Illness Outcomes Study: An Observational Study on Protocols and Mortality in Intensive Care Units. J Clin Trials. 2011 Sep 23;2011(3):55-65.

Early identification of patients at risk of acute lung injury: Evaluation of lung injury prediction score in a multicenter cohort study
Gajic O, Dabbagh O, Park PK, Adesanya A, Chang SY, Hou P, Anderson H 3rd, Hoth JJ, Mikkelsen ME, Gentile NT, Gong MN, Talmor D, Bajwa E, Watkins TR, Festic E, Yilmaz M, Iscimen R, Kaufman DA, Esper AM, Sadikot R, Douglas I, Sevransky J, Malinchoc M . U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG-LIPS). Early identification of patients at risk of acute lung injury: evaluation of lung injury prediction score in a multicenter cohort study. Am J Respir Crit Care Med. 2011 Feb 15;183(4):462-70.

Off-label medication use in adult critical care patients
Lat I, Micek S, Janzen J, Cohen H, Olsen K, Haas C. Off-label medication use in adult critical care patients. J Crit Care. 2011 Feb; 26(1): 89-94.

The United States critical illness and injury trials group: An introduction
Cobb JP, Cairns CB, Bulger E, Wong HR, Parsons PE, Angus DC, Gentile NT, Hoyt DB, Schwinn DA, Wiener-Kronish JP, Upperman JS. The United States critical illness and injury trials group: an introduction. J Trauma. 2009 Aug;67(2 Suppl):S159-60.

(USCIITG–LIPS 1) Towards prevention of acute lung injury: Frequency and outcomes of emergency department patients at-risk – a multicenter cohort study
Hou PC, Elie-Turenne MC, Mitani A, Barry JM, Kao EY, Cohen JE, Frendl G, Gajic O, Gentile NT. US Critical Illness and Injury Trials Group: Lung Injury Prevention Study Investigators (USCIITG–LIPS 1). Towards prevention of acute lung injury: frequency and outcomes of emergency department patients at-risk – a multicenter cohort study. Int J Emerg Med. 2012 May 27;5(1):22.