Times:
2:00 p.m. - 3:30 p.m. Eastern
1:00 p.m. - 2:30 p.m. Central
12:00 p.m. - 1:30 p.m. Mountain
11:00 a.m. - 12:30 p.m. Pacific

Program Overview:
This webcast will present the current understanding of mitochondrial function and oxidative stress in critical illness. Delivering oxygen to target tissues is only helpful if those target tissues can use oxygen to create energy.  Emerging literature suggests that mitochondrial dysfunction represents an important pathophysiologic aspect of adult and pediatric critical illness.  Failure of cellular energetics at the mitochondrial level represents an important area of biology in 2012 and an attractive target for future therapies.

Learning Objectives:
Upon completion of this webcast participants will be able to:

• Demonstrate an understanding of the biological processes underlying normal mitochondrial function.
• Identify pathological changes in mitochondrial function in the setting of critical illness (e.g. energy failure, effects of reactive oxygen species).
• Identify experimental approaches to the modulation of mitochondrial function with potential applications in the pediatric intensive care unit.

Schedule: (Time Reflects CDT)

1:00 p.m. - 1:05 p.m. Introduction
       Mark W. Hall, MD, FCCM (Moderator)

1:05 p.m. - 1:35 p.m. Normal Mitochondrial Function and Pathological Changes 
       Elliot Crouser, MD

1:35 p.m. – 2:05 p.m. Experimental Approaches to the Modulation of the Mitochondrial Function        
       Hülya Bayir, MD

2:05 p.m. - 2:30 p.m. Question and Answer Session

Faculty:

	Mark W. Hall, MD, FCCM Critical Care Pediatrician Nationwide Children's Hospital
	Elliot Crouser, MD Associate Professor Ohio State University Medical Center
	Hülya Bayir,D Associate Professor, Department of Critical Care Medicine University of Pittsburgh

Target Audience
This continuing medical education offering is intended to meet the needs of all physicians, nurses, pharmacists, and other providers who care for the critically ill patient.

Type of Activity
This activity is intended to apply best practice methods for managing the ICU patient.

Competencies
SCCM supports recommendations that will promote lifelong learning through continuing education. SCCM promotes activities that encourage the highest quality in education that will enhance knowledge, competence or performance in critical care practice. This activity will meet the following competencies:

Clinical Knowledge
Quality Improvement and Patient safety 
Multiprofessional Teamwork
Communication
Patient and Family satisfaction

This program is supported, in part, by an Unrestricted medical education grant from IKARIA, Inc.

CE/CME Credit

Physicians
Accreditation Statement: The Society of Critical Care Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Designation Statement: The Society of Critical Care Medicine designates this live educational activity for a maximum of 1.5 AMA PRA Category 1 credits™.
Each physician should claim only those hours of credit that he/she actually spent in the educational activity.

Nurses
This program has been approved by the California Board of Registered Nursing, Provider No. 8181, for up to 1.5 contact hours.

Pharmacists
The Society of Critical Care Medicine is accredited by the Accreditation Council for Pharmacy Education (ACPE) as a provider of continuing pharmacy education. This course provides up to 1.5 contact hours of continuing education credit (XXXXXXXXXXXXXX). Pharmacists must complete the online verification form to confirm sessions attended and upon completion, a certificate can be downloaded and printed.

Obtaining CE/CME credits
To obtain credit, please complete the evaluation. You will be prompted to complete your CE/CME credit application, for the live activity only, by logging in with your SCCM customer ID and password.

You will need your SCCM customer ID to continue. Your password should be your last name, unless you have changed it. If you have any questions, please contact education@sccm.org or call +1-847-827-6869.

Reprint a copy of the CE/CME certificate.

System Requirements
Audio speakers
PC-based attendees:
Windows® 2000, XP Home, XP Pro, 2003 Server, Vista